Publications
Hellingman A, Sifoniou K, Buser T, Thommen B.T, Walz A, Passecker A, Collins J, Hupfeld M, Wittlin S, Witmer K, Brancucci N.M.B. Next generation chemiluminescent probes for antimalarial drug discovery. ACS Infect Dis. 2024(in press). DOI: 10.1021/acsinfecdis.3c00707
Thommen B.T, Dziekan J.M, Achcar F, Tjia S, Passecker A, Buczak K, Gumpp C, Schmidt A, Rottmann M, Grüring C, Marti M, Bozdech Z, Brancucci N.M.B. Genetic validation of PfFKBP35 as an antimalarial drug target. eLife. 2023;12(RP86975). DOI: 10.7554/eLife.86975
Thommen B.T, Passecker A, Buser T, Hitz E, Voss T.S, Brancucci N.M.B. Revisiting the effect of pharmaceuticals on transmission stage formation in the malaria parasite Plasmodium falciparum. Front Cell Infect Microbiol. 2022;12:802341. DOI: 10.3389/fcimb.2022.802341
Boltryk S.D, Passecker A, Alder A, Carrington E, van de Vegte-Bolmer M, van Gemert G.J, van der Starre A, Beck H.P, Sauerwein R.W, Kooij T.W.A, Brancucci N.M.B, Proellochs N.I, Gilberger T.W, Voss T.S. CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research. Nat Commun. 2021;12:4806. DOI: 10.1038/s41467-021-24954-4
Bui H.T.N, Passecker A, Brancucci N.M.B, Voss T.S. Investigation of heterochromatin protein 1 function in the malaria parasite Plasmodium falciparum using a conditional domain deletion and swapping approach. mSphere. 2021;6(1):e01220-20. DOI: 10.1128/mSphere.01220-20
Hitz E, Grüninger O, Passecker A, Wyss M, Scheurer C, Wittlin S, Beck H.P, Brancucci N.M.B, Voss T.S. The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis. Commun Biol. 2021;4(1):336. DOI: 10.1038/s42003-021-01873-0
Hitz E, Wiedemar N, Passecker A, Graça B.A.S, Scheurer C, Wittlin S, Brancucci N.M.B, Vakonakis I, Mäser P, Voss T.S. The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites. PLoS Biol. 2021;19(12):e3001483. DOI: 10.1371/journal.pbio.3001483
Warncke J.D, Passecker A, Kipfer E, Brand F, Perez-Martinez L, Proellochs N.I, Kooij T.W.A, Butter F, Voss T.S, Beck H.P. The PHIST protein GEXP02 targets the host cytoskeleton during sexual development of Plasmodium falciparum. Cell Microbiol. 2020;22(2):e13123. DOI: 10.1111/cmi.13123
Day J, Passecker A, Beck H.P, Vakonakis I. The Plasmodium falciparum Hsp70-x chaperone assists the heat stress response of the malaria parasite. FASEB J. 2019;33(12):14611-14624. DOI: 10.1096/fj.201901741R