Publications

Ley S.D, Pillay S, Streicher E.M, van der Heijden Y.F, Sirgel F, Derendinger B, de Kock M, Gagneux S, Warren R.M, Theron G, de Vos M. Melting the eis: non-detection of kanamycin resistance markers by routine diagnostic tests and identification of new eis-promoter variants. Antimicrob Agents Chemother. 2021;65(7):e0250220. DOI: 10.1128/AAC.02502-20

Menardo F, Rutaihwa L.K, Zwyer M, Borrell S, Comas I, Conceicao E.C, Coscolla M, Cox H, Joloba M, Dou H.Y, Feldmann J, Fenner L, Fyfe J, Gao Q, Garcia de Viedma D, Garcia-Basteiro A.L, Gygli S.M, Hella J, Hiza H, Jugheli L, Kamwela L, Kato-Maeda M, Liu Q, Ley S.D, Loiseau C, Mahasirimongkol S, Malla B, Palittapongarnpim P, Rakotosamimanana N, Rasolofo V, Reinhard M, Reither K, Sasamalo M, Silva Duarte R, Sola C, Suffys P, Batista Lima K.V, Yeboah-Manu D, Beisel C, Brites D, Gagneux S. Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim. F1000Res. 2021;10:60. DOI: 10.12688/f1000research.28318.1

Mogashoa T, Melamu P, Derendinger B, Ley S.D, Streicher E.M, Iketleng T, Mupfumi L, Mokomane M, Kgwaadira B, Rankgoane-Pono G, Tsholofelo T.T, Kasvosve I, Moyo S, Warren R.M, Gaseitsiwe S. Detection of second line drug resistance among drug resistant Mycobacterium tuberculosis isolates in Botswana. Pathogens. 2019;8(4):E208. DOI: 10.3390/pathogens8040208

Mogashoa T, Melamu P, Ley S.D, Streicher E.M, Iketleng T, Kelentse N, Mupfumi L, Mokomane M, Kgwaadira B, Novitsky V, Kasvosve I, Moyo S, Warren R.M, Gaseitsiwe S. Genetic diversity of Mycobacterium tuberculosis strains circulating in Botswana. PLoS One. 2019;14(5):e0216306. DOI: 10.1371/journal.pone.0216306

Rutaihwa L, Menardo F, Stucki D, Gygli S.M, Ley S.D, Malla B, Feldmann J, Borrell S, Beisel C, Middelkoop K, Carter J.E, Diero L, Ballif M, Jugheli L, Reither K, Fenner L, Brites D, Gagneux S. Multiple introductions of Mycobacterium tuberculosis lineage 2-Beijing into Africa over centuries. Front Ecol Evol. 2019;7:112. DOI: 10.3389/fevo.2019.00112

Stucki D, Brites D, Jeljeli L, Coscolla M, Liu Q, Trauner A, Fenner L, Rutaihwa L, Borrell S, Luo T, Gao Q, Kato-Maeda M, Ballif M, Egger M, Macedo R, Mardassi H, Moreno M, Vilanova G.T, Fyfe J, Globan M, Thomas J, Jamieson F, Guthrie J.L, Asante-Poku A, Yeboah-Manu D, Wampande E, Ssengooba W, Joloba M, Boom W.H, Basu I, Bower J, Saraiva M, Vasconcellos S.E, Suffys P, Koch A, Wilkinson R, Gail-Bekker L, Malla B, Ley S.D, Beck H.P, de Jong B.C, Toit K, Sanchez-Padilla E, Bonnet M, Gil-Brusola A, Frank M, Penlap Beng V.N, Eisenach K, Alani I, Ndung'u P.W, Revathi G, Gehre F, Akter S, Ntoumi F, Stewart-Isherwood L, Ntinginya N.E, Rachow A, Hoelscher M, Cirillo D.M, Skenders G, Hoffner S, Bakonyte D, Stakenas P, Diel R, Crudu V, Moldovan O, Al-Hajoj S, Otero L, Barletta F, Carter E.J, Diero L, Supply P, Comas I, Niemann S, Gagneux S. Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages. Nat Genet. 2016;48(12):1535-1543. DOI: 10.1038/ng.3704

Ley S, Carter R, Millan K, Phuanukoonnon S, Pandey S, Coulter C, Siba P, Beck H.P. Non-tuberculous mycobacteria: baseline data from three sites in Papua New Guinea, 2010-2012. Western Pac Surveill Response J. 2015;6(4):24-29. DOI: 10.5365/WPSAR.2015.6.2.004

Ley S.D, Harino P, Vanuga K, Kamus R, Carter R, Coulter C, Pandey S, Feldmann J, Ballif M, Siba P.M, Phuanukoonnon S, Gagneux S, Beck H.P. Diversity of Mycobacterium tuberculosis and drug resistance in different provinces of Papua New Guinea. BMC Microbiol. 2014;14:307. DOI: 10.1186/s12866-014-0307-2

Ley S.D, Riley I, Beck H.P. Tuberculosis in Papua New Guinea: from yesterday until today. Microbes Infect. 2014;16(8):607-614. DOI: 10.1016/j.micinf.2014.06.012

Ley S.D. Molecular epidemiology of tuberculosis in selected sites across Papua New Guinea. Basel: Univ. Basel, 2014. Doctoral Thesis, University of Basel, Faculty of Science DOI: 10.5451/unibas-006275629

Ballif M, Harino P, Ley S, Carter R, Coulter C, Niemann S, Borrell S, Fenner L, Siba P, Phuanukoonnon S, Gagneux S, Beck H.P. Genetic diversity of Mycobacterium tuberculosis in Madang, Papua New Guinea. Int J Tuberc Lung Dis. 2012;16(8):1100-1107. DOI: 10.5588/ijtld.11.0779

Ballif M, Harino P, Ley S, Coscolla M, Niemann S, Carter R, Coulter C, Borrell S, Siba P, Phuanukoonnon S, Gagneux S, Beck H.P. Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea. BMC Microbiol. 2012;12:191. DOI: 10.1186/1471-2180-12-191

Senn N, Rarau P, Stanisic D.I, Robinson L, Barnadas C, Manong D, Salib M, Iga J, Tarongka N, Ley S, Rosanas-Urgell A, Aponte J.J, Zimmerman P.A, Beeson J.G, Schofield L, Siba P, Rogerson S.J, Reeder J.C, Mueller I. Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial. PLoS Med. 2012;9(3):e1001195. DOI: 10.1371/journal.pmed.1001195

Hodel E.M, Ley S.D, Qi W, Ariey F, Genton B, Beck H.P. A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs. Malar J. 2009;8:285. DOI: 10.1186/1475-2875-8-285

Beck H.P, Ley S. Monitoring of malaria drug resistance associated SNPs in P. falciparum on microarray. In: Ljungström I,Perlmann H,Schichtherle M,Scherf A,Wahlgen M, eds. Methods in Malaria Research, 248-257. Manassas: MR4/ATCC, 2008

Müller J, Ley S, Felger I, Hemphill A, Müller N. Identification of differentially expressed genes in a Giardia lamblia WB C6 clone resistant to nitazoxanide and metronidazole. J Antimicrob Chemother. 2008;62:72-82

Sternberg J.M, Tait A, Haley S, Wells J.M, Le Page R.W.F, Schweizer J, Jenni L. Gene exchange in African trypanosomes: characterisation of a new hybrid genotype. Mol Biochem Parasitol. 1988;27(2-3):191-200

Sternberg J.M, Tait A, Haley S, Schweizer J, Jenni L. The inheritance of chromosonal and kinetoplast variants in T. brucei spp.. In: Agabian N,Goodman H,Nogueira N, eds. Molecular strategies of parasitic invasion: proceedings of MacArthur Foundation-UCLA symposium held in Park City, Utah, january 26-31, 1987, 253-258. New York: Alan R. Liss, 1987