Brunner N.C, Karim A, Athieno P, Kimera J, Tumukunde G, Angiro I, Signorell A, Delvento G, Lee T.T, Lambiris M, Ogwal A, Nakiganda J, Mpanga F, Kagwire F, Amutuhaire M, Burri C, Lengeler C, Awor P, Hetzel M.W. Starting at the community: treatment-seeking pathways of children with suspected severe malaria in Uganda. PLOS Glob Public Health. 2023;3(7):e0001949. DOI: 10.1371/journal.pgph.0001949

2023
Journal Article
PubMed

Hetzel M.W, Awor P, Tshefu A, Omoluabi E, Burri C, Signorell A, Lambiris M.J, Visser T, Cohen J.M, Buj V, Lengeler C. Pre-referral rectal artesunate: no cure for unhealthy systems. Lancet Infect Dis. 2023;23(6):e213-e217. DOI: 10.1016/S1473-3099(22)00762-9

2023
Journal Article
PubMed

Hetzel M.W, Okitawutshu J, Tshefu A, Omoluabi E, Awor P, Signorell A, Kwiatkowski M, Lambiris M.J, Visser T, Cohen J.M, Buj V, Burri C, Lengeler C. Pre-referral rectal artesunate is no "magic bullet" in weak health systems. BMC Med. 2023;21:119. DOI: 10.1186/s12916-023-02777-y

2023
Journal Article
PubMed

Lambiris M.J, Venga G.N, Ssempala R, Balogun V, Galactionova K, Musiitwa M, Kagwire F, Olosunde O, Emedo E, Luketa S, Sangare M, Buj V, Delvento G, Tshefu A, Okitawutshu J, Omoluabi E, Awor P, Signorell A, Hetzel M.W, Lee T.T, Brunner N.C, Cereghetti N, Visser T, Napier H.G, Burri C, Lengeler C. Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and constraints. Lancet Glob Health. 2023;11(2):e256-e264. DOI: 10.1016/S2214-109X(22)00507-1

2023
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Mäser P, Bernhard S, Brun R, Burri C, Gagneux S, Hetzel M.W, Kaiser M, Lengeler C, Pluschke G, Reus E, Rottmann M, Utzinger J, Warryn L, Wittlin S, Keiser J. Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases. Chimia (Aarau). 2023;77(9):593-606. DOI: 10.2533/chimia.2023.593

2023
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PubMed

Okitawutshu J, Tshefu A, Kalenga J.C, Delvento G, Burri C, Hetzel M.W, Lengeler C, Signorell A. Assessing caregivers' perceptions of treatment-seeking for suspected severe malaria in the Democratic Republic of the Congo. Malar J. 2023;22:308. DOI: 10.1186/s12936-023-04737-6

2023
Journal Article
PubMed

Signorell A, Awor P, Okitawutshu J, Tshefu A, Omoluabi E, Hetzel M.W, Athieno P, Kimera J, Tumukunde G, Angiro I, Kalenga J.C, Akano B.K, Ayodeji K, Okon C, Yusuf O, Delvento G, Lee T.T, Brunner N.C, Lambiris M.J, Okuma J, Cereghetti N, Buj V, Visser T, Napier H.G, Lengeler C, Burri C. Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: an operational study. PLoS Med. 2023;20(2):e1004189. DOI: 10.1371/journal.pmed.1004189

2023
Journal Article
PubMed

Thawer S.G, Golumbeanu M, Lazaro S, Chacky F, Munisi K, Aaron S, Molteni F, Lengeler C, Pothin E, Snow R.W, Alegana V.A. Spatio-temporal modelling of routine health facility data for malaria risk micro-stratification in mainland Tanzania. Sci Rep. 2023;13:10600. DOI: 10.1038/s41598-023-37669-x

2023
Journal Article
PubMed

Awor P, Kimera J, Athieno P, Tumukunde G, Okitawutshu J, Tshefu A, Omoluabi E, Signorell A, Brunner N, Kalenga J.C, Akano B, Ayodeji K, Okon C, Yusuf O, Delvento G, Lee T, Burri C, Lengeler C, Hetzel M.W. Acceptability of pre-referral rectal artesunate for severe malaria in children under 5 years by health workers and caregivers in the Democratic Republic of the Congo, Nigeria and Uganda. Malar J. 2022;21:322. DOI: 10.1186/s12936-022-04348-7

2022
Journal Article
PubMed

Awor P, Kimera J, Brunner N.C, Athieno P, Tumukunde G, Angiro I, Signorell A, Delvento G, Lee T, Amutuhaire M, Opigo J, Kaggwa F.M, Kagwire F, Nakiganda J, Burri C, Lengeler C, Hetzel M.W. Care seeking and treatment of febrile children with and without danger signs of severe disease in northern Uganda: results from three household surveys (2018-2020). Am J Trop Med Hyg. 2022;107(4):934–938. DOI: 10.4269/ajtmh.21-1132

2022
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PubMed

Brunner N.C, Omoluabi E, Awor P, Okitawutshu J, Tshefu Kitoto A, Signorell A, Akano B, Ayodeji K, Okon C, Yusuf O, Athieno P, Kimera J, Tumukunde G, Angiro I, Kalenga J.C, Delvento G, Lee T.T, Lambiris M.J, Ross A, Cereghetti N, Visser T, Napier H.G, Buj V, Burri C, Lengeler C, Hetzel M.W. Prereferral rectal artesunate and referral completion among children with suspected severe malaria in the Democratic Republic of the Congo, Nigeria and Uganda. BMJ Glob Health. 2022;7(5):e008346. DOI: 10.1136/bmjgh-2021-008346

2022
Journal Article
PubMed

Fink G, Mrema S, Abdulla S, Kachur P, Khatib R, Lengeler C, Masanja H, Okumu F, Schellenberg D. Mosquito net use in early childhood and survival to adulthood in Tanzania. N Engl J Med. 2022;386:428-436. DOI: 10.1056/NEJMoa2112524

2022
Journal Article
PubMed

Hetzel M.W, Okitawutshu J, Tshefu A, Omoluabi E, Awor P, Signorell A, Brunner N.C, Kalenga J.C, Akano B.K, Ayodeji K, Okon C, Yusuf O, Athieno P, Kimera J, Tumukunde G, Angiro I, Delvento G, Lee T.T, Lambiris M.J, Kwiatkowski M, Cereghetti N, Visser T, Napier H.G, Cohen J.M, Buj V, Burri C, Lengeler C. Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study. BMC Med. 2022;20:343. DOI: 10.1186/s12916-022-02541-8

2022
Journal Article
PubMed

Lengeler C, Burri C, Awor P, Athieno P, Kimera J, Tumukunde G, Angiro I, Tshefu A, Okitawutshu J, Kalenga J.-C, Omoluabi E, Akano B, Ayodeji K, Okon C, Yusuf O, Brunner N.C, Delvento G, Lee T, Lambiris M.J, Visser T, Napier H.G, Cohen J.M, Buj V, Signorell A, Hetzel Manuel W, Caramal Consortium. Community access to rectal artesunate for malaria (CARAMAL): a large-scale observational implementation study in the Democratic Republic of the Congo, Nigeria and Uganda. PLoS Glob Public Health. 2022;2(9):e0000464. DOI: 10.1371/journal.pgph.0000464

2022
Journal Article

Okitawutshu J, Signorell A, Kalenga J.C, Mukomena E, Delvento G, Burri C, Mwaluke F, Buj V, Sangare M, Luketa S, Brunner N, Lee T, Hetzel M, Lengeler C, Tshefu A. Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo. Malar J. 2022;21:274. DOI: 10.1186/s12936-022-04296-2

2022
Journal Article
PubMed

Polonsky J.A, Bhatia S, Fraser K, Hamlet A, Skarp J, Stopard I.J, Hugonnet S, Kaiser L, Lengeler C, Blanchet K, Spiegel P. Feasibility, acceptability, and effectiveness of non-pharmaceutical interventions against infectious diseases among crisis-affected populations: a scoping review. Infect Dis Poverty. 2022;11(1):14. DOI: 10.1186/s40249-022-00935-7

2022
Journal Article
PubMed

Runge M, Thawer S.G, Molteni F, Chacky F, Mkude S, Mandike R, Snow R.W, Lengeler C, Mohamed A, Pothin E. Sub-national tailoring of malaria interventions in mainland Tanzania: simulation of the impact of strata-specific intervention combinations using modelling. Malar J. 2022;21:92. DOI: 10.1186/s12936-022-04099-5

2022
Journal Article
PubMed

Thawer S.G, Golumbeanu M, Munisi K, Aaron S, Chacky F, Lazaro S, Mohamed A, Kisoka N, Lengeler C, Molteni F, Ross A, Snow R.W, Pothin E. The use of routine health facility data for micro-stratification of malaria risk in mainland Tanzania. Malar J. 2022;21:345. DOI: 10.1186/s12936-022-04364-7

2022
Journal Article
PubMed

Yin J.H, Lengeler C, Tanner M, Zhou X.N. A malaria-free China: global importance and key experience. Adv Parasitol. 2022;116:xv-xix. DOI: 10.1016/S0065-308X(22)00027-6

2022
Journal Article
PubMed

Arn Karoline. Christian Lengeler: Malaria breitet sich wieder aus [Radio Broadcast] [Internet]. Zürich: SRF, 2021. [Date Accessed: 21.04.2021]. Available from: https://podcasts.srf.ch/world/audio/Tagesgespraech_21-04-2021-1300.1619006356184.mp3

2021
Podcast

Awor P, Khim N, Coppée R, Rondepierre L, Roesch C, Khean C, Kul C, Eam R, Lorn T, Athieno P, Kimera J, Clain J, Ringwald P, Signorell A, Lengeler C, Burri C, Ariey F, Hetzel M.W, Witkowski B. Clonal expansion of artemisinin-resistant Plasmodium falciparum in Uganda is associated with substandard treatment practices. Lancet. 2021(in press). DOI: 10.2139/ssrn.3974542

2021
Journal Article

Lee T.T, Omoluabi E, Ayodeji K, Yusuf O, Okon C, Brunner N.C, Delvento G, Signorell A, Lambiris M, Kwiatkowski M, Burri C, Lengeler C, Emedo E, Cheshi F, Hetzel M.W. Treatment-seeking for children with suspected severe malaria attending community health workers and primary health centres in Adamawa State, Nigeria. medRxiv. 2021(in press). DOI: 10.1101/2021.12.01.21267130

2021
Journal Article

Mudji J, Yaka K, Olarewaju V, Lengeler C. Prevalence and risk factors for malaria in pregnancy in Vanga, Democratic Republic of Congo. Afr J Reprod Health. 2021;25(5):14-24. DOI: 10.29063/ajrh2021/v25i5.2

2021
Journal Article

Runge M, Molteni F, Mandike R, Snow R.W, Lengeler C, Mohamed A, Pothin E. Applied mathematical modelling to inform national malaria policies, strategies and operations in Tanzania. Malar J. 2020;19:101. DOI: 10.1186/s12936-020-03173-0

2020
Journal Article
PubMed

Runge M, Snow R.W, Molteni F, Thawer S, Mohamed A, Mandike R, Giorgi E, Macharia P.M, Smith T.A, Lengeler C, Pothin E. Simulating the council-specific impact of anti-malaria interventions: a tool to support malaria strategic planning in Tanzania. PLoS One. 2020;15(2):e0228469. DOI: 10.1371/journal.pone.0228469

2020
Journal Article
PubMed

Thawer S.G, Chacky F, Runge M, Reaves E, Mandike R, Lazaro S, Mkude S, Rumisha S.F, Kumalija C, Lengeler C, Mohamed A, Pothin E, Snow R.W, Molteni F. Sub-national stratification of malaria risk in mainland Tanzania: a simplified assembly of survey and routine data. Malar J. 2020;19:177. DOI: 10.1186/s12936-020-03250-4

2020
Journal Article
PubMed

Yukich J, Stuck L, Scates S, Wisniewski J, Chacky F, Festo C, Kabulika G, Dimoso K, Mandike R, Greer G, Serbantez N, Elisaria E, Nyoni W, Dadi D, Akim I, Lengeler C, Brown N, Koenker H. Sustaining LLIN coverage with continuous distribution: the school net programme in Tanzania. Malar J. 2020;19:158. DOI: 10.1186/s12936-020-03222-8

2020
Journal Article
PubMed

Brunner N.C, Chacky F, Mandike R, Mohamed A, Runge M, Thawer S.G, Ross A, Vounatsou P, Lengeler C, Molteni F, Hetzel M.W. The potential of pregnant women as a sentinel population for malaria surveillance. Malar J. 2019;18:370. DOI: 10.1186/s12936-019-2999-0

2019
Journal Article
PubMed

Lechthaler F, Matthys B, Lechthaler-Felber G, Likwela J.L, Mavoko H.M, Rika J.M, Mutombo M.M, Ruckstuhl L, Barczyk J, Shargie E, Prytherch H, Lengeler C. Trends in reported malaria cases and the effects of malaria control in the Democratic Republic of the Congo. PLoS One. 2019;14(7):e0219853. DOI: 10.1371/journal.pone.0219853

2019
Journal Article
PubMed

Renggli S, Mayumana I, Mboya D, Charles C, Mshana C, Kessy F, Glass T.R, Lengeler C, Schulze A, Aerts A, Pfeiffer C. Towards improved health service quality in Tanzania: contribution of a supportive supervision approach to increased quality of primary healthcare. BMC Health Serv Res. 2019;19:848. DOI: 10.1186/s12913-019-4648-2

2019
Journal Article
PubMed

Renggli S, Mayumana I, Mboya D, Charles C, Mshana C, Kessy F, Glass T.R, Pfeiffer C, Schulze A, Aerts A, Lengeler C. Towards improved health service quality in Tanzania: appropriateness of an electronic tool to assess quality of primary healthcare. BMC Health Serv Res. 2019;19:55. DOI: 10.1186/s12913-019-3908-5

2019
Journal Article
PubMed

Renggli S, Mayumana I, Mshana C, Mboya D, Kessy F, Tediosi F, Pfeiffer C, Aerts A, Lengeler C. Looking at the bigger picture: how the wider health financing context affects the implementation of the Tanzanian Community Health Funds. Health Policy Plan. 2019;34(1):12-23. DOI: 10.1093/heapol/czy091

2019
Journal Article
PubMed

Chacky F, Runge M, Rumisha S.F, Machafuko P, Chaki P, Massaga J.J, Mohamed A, Pothin E, Molteni F, Snow R.W, Lengeler C, Mandike R. Nationwide school malaria parasitaemia survey in public primary schools, the United Republic of Tanzania. Malar J. 2018;17:452. DOI: 10.1186/s12936-018-2601-1

2018
Journal Article
PubMed

Koenker H, Arnold F, Ba F, Cissé M, Diouf L, Eckert E, Erskine M, Florey L, Fotheringham M, Gerberg L, Lengeler C, Lynch M, Mnzava A, Nasr S, Ndiop M, Poyer S, Renshaw M, Shargie E, Taylor C, Thwing J, Van Hulle S, Ye Y, Yukich J, Kilian A. Assessing whether universal coverage with insecticide-treated nets has been achieved: is the right indicator being used?. Malar J. 2018;17:355. DOI: 10.1186/s12936-018-2505-0

2018
Journal Article
PubMed

Lengeler C, Hetzel M, Signorell A, Awor P, Tshefu A, Okitawutshu J, Omoluabi E, Nepomnyashchiy L, Fast J, Ramachandra S, Goldstein R, Buj V, Burri C. Introducing rectal artesunate in community settings and evaluating its impact. 7th MIM Pan African Malaria Conference. Dakar, Senegal, 2018

2018
Conference Paper

Maia M.F, Kliner M, Richardson M, Lengeler C, Moore S.J. Mosquito repellents for malaria prevention. Cochrane Database Syst Rev. 2018(2):CD011595. DOI: 10.1002/14651858.CD011595.pub2

2018
Journal Article
PubMed

Pryce J, Richardson M, Lengeler C. Insecticide-treated nets for preventing malaria. Cochrane Database Syst Rev. 2018;11:CD000363. DOI: 10.1002/14651858.CD000363.pub3

2018
Journal Article
PubMed

Renggli S, Mayumana I, Mboya D, Charles C, Maeda J, Mshana C, Kessy F, Tediosi F, Pfeiffer C, Schulze A, Aerts A, Lengeler C. Towards improved health service quality in Tanzania: An approach to increase efficiency and effectiveness of routine supportive supervision. PLoS One. 2018;13(9):e0202735. DOI: 10.1371/journal.pone.0202735

2018
Journal Article
PubMed

Signorell A, Hetzel M, Awor P, Tshefu A, Okitawutshu J, Omoluabi E, Nepomnyashchiy L, Burri C, Lengeler C. CARAMAL: addressing the remaining burden of malaria deaths by optimizing the use of rectla artesunate. 7th MIM Pan African Malaria Conference. Dakar, Senegal, 2018

2018
Conference Paper

Délétroz Stéphane, RTS Radio Télévision Suisse. L'OMS s'allie à Swiss TPH contre le paludisme [Radio Broadcast] [Internet]: RTS Radio Télévision Suisse, 2017. [Date Accessed: 10.08.2017]. Available from: https://www.rts.ch/play/radio/cqfd/audio/loms-sallie-a-swiss-tph-contre-le-paludisme?id=8534270#?station=a9e7621504c6959e35c3ecbe7f6bed0446cdf8da

2017
Podcast