Publications

Adebayo G, Ayanda O.I, Rottmann M, Ajibaye O.S, Oduselu G, Mulindwa J, Ajani O.O, Aina O, Mäser P, Adebiyi E. The importance of murine models in determining in vivo pharmacokinetics, safety, and efficacy in antimalarial drug discovery. Pharmaceuticals (Basel). 2025;18(3). DOI: 10.3390/ph18030424

Dupouy B, Cotos L, Binder A, Slavikova L, Rottmann M, Mäser P, Jacquemin D, Ganter M, Davioud-Charvet E, Elhabiri M. Click coupling of flavylium dyes with plasmodione analogues: towards new redox-sensitive pro-fluorophores. Chemistry. 2025;31(6):e202403691. DOI: 10.1002/chem.202403691

Dupouy B, Karpstein T, Häberli C, Cal M, Rottmann M, Mäser P, Keiser J, Elhabiri M, Davioud-Charvet E. Synthesis of 1,2,3-triazole-methyl-menadione derivatives: evaluation of electrochemical and antiparasitic properties against two blood-dwelling parasites. ChemMedChem. 2025;20(6):e202400731. DOI: 10.1002/cmdc.202400731

Kaminsky R, Mäser P. Global impact of parasitic infections and the importance of parasite control. Front Parasitol. 2025;4:1546195. DOI: 10.3389/fpara.2025.1546195

Ortiz J.E, Piñeiro M, Kaiser M, Mäser P, Bastida J, Feresin G.E. Anti-trypanosomatid and antiplasmodial activities of alkaloids from Hippeastrum species. Chem Biodivers. 2025(in press). DOI: 10.1002/cbdv.202500015

Presser A, Blaser G, Pferschy-Wenzig E.M, Kaiser M, Mäser P, Schuehly W. Pharmacomodulation of the redox-active lead plasmodione: synthesis of substituted 2-benzylnaphthoquinone derivatives, antiplasmodial activities, and physicochemical properties. Int J Mol Sci. 2025;26(5). DOI: 10.3390/ijms26052114

Rimle L, Pliatsika D, Arnold N, Kurth S, Kaiser M, Mäser P, Kemmler M, Adams M, Riedl R, von Ballmoos C. Dissecting structural requirements of leucinostatin a derivatives for antiprotozoal activity and mammalian toxicity. J Med Chem. 2025;68(4):4237-4258. DOI: 10.1021/acs.jmedchem.4c01989

Schäfer L, Cal M, Kaiser M, Mäser P, Schmidt T.J. Antiprotozoal aminosteroids from Pachysandra terminalis. Molecules. 2025;30(5). DOI: 10.3390/molecules30051093

Baert L, Rudy S, Pellisson M, Doll T, Rocchetti R, Kaiser M, Mäser P, Müller M. Induced pluripotent stem cell-derived human macrophages as an infection model for Leishmania donovani. PLoS Negl Trop Dis. 2024;18(1):e001155. DOI: 10.1371/journal.pntd.0011559

Bizzarri L, Steinbrunn D, Quennesson T, Lacour A, Bianchino G.I, Bravo P, Chaignon P, Lohse J, Mäser P, Seemann M, Calenbergh S.V, Hirsch A.K.H, Hahne H. Studying target-engagement of anti-infectives by solvent-induced protein precipitation and quantitative mass spectrometry. ACS Infect Dis. 2024;10(12):4087-4102. DOI: 10.1021/acsinfecdis.4c00417

Bravo P, Bizzarri L, Steinbrunn D, Lohse J, Hirsch A.K.H, Mäser P, Rottmann M, Hahne H. Integral solvent-induced protein precipitation for target-engagement studies in Plasmodium falciparum. ACS Infect Dis. 2024;10(12):4073-4086. DOI: 10.1021/acsinfecdis.4c00418

Burri C, Mäser P, Chappuis F. Human African trypanosomiasis. In: Farrar J,Hotez P.J,Junghanss T,Kang G,Lalloo D,White N.J,Garcia P.J, eds. Manson's Tropical Diseases, 623-635. Amsterdam: Elsevier, 2024. DOI: 10.1016/B978-0-7020-7959-7.00051-8

Cesar-Rodo E, Dupouy B, Häberli C, Strub J.M, Williams D.L, Mäser P, Rottmann M, Keiser J, Lanfranchi D.A, Davioud-Charvet E. Regioselective synthesis of potential non-quinonoid prodrugs of plasmodione: antiparasitic properties against two hemoglobin-feeding parasites and drug metabolism studies. Molecules. 2024;29(22):5268. DOI: 10.3390/molecules29225268

Chollet V, Rapp E, Velarde-Rodriguez M, Gold M, Mäser P, Fehr J, Monnier N, Jackson Y, Albajar-Viñas P, Martinez de Salazar P. Chagas disease in Switzerland: current situation, challenges and opportunities. Swiss Med Wkly. 2024;154(12):3719. DOI: 10.57187/s.3719

Dupouy B, Donzel M, Roignant M, Charital S, Keumoe R, Yamaryo-Botté Y, Feckler A, Bundschuh M, Bordat Y, Rottmann M, Mäser P, Botté C.Y, Blandin S.A, Besteiro S, Davioud-Charvet E. 3-Benzylmenadiones and their heteroaromatic analogues target the apicoplast of apicomplexa parasites: synthesis and bioimaging studies. ACS Infect Dis. 2024;10(10):3553-3576. noOA. DOI: 10.1021/acsinfecdis.4c00304

Duwor S, Brites D, Mäser P. Phylogenetic analysis of pyruvate-ferredoxin oxidoreductase, a redox enzyme involved in the pharmacological activation of nitro-based prodrugs in bacteria and protozoa. Biology (Basel). 2024;13(3):178. DOI: 10.3390/biology13030178

Hamid A, Mäser P, Mahmoud A.B. Drug repurposing in the chemotherapy of infectious diseases. Molecules. 2024;29(3):635. DOI: 10.3390/molecules29030635

Hauser D.A, Kaiser M, Mäser P, Albisetti A. Venturicidin A affects the mitochondrial membrane potential and induces kDNA loss in Trypanosoma brucei. Antimicrob Agents Chemother. 2024;68(7):e0167123. DOI: 10.1128/aac.01671-23

Seebacher W, Hoffelner M, Belaj F, Kaiser M, Mäser P, Saf R, Pferschy-Wenzig E.M, Weis R. Tetrahydropyridinylidene ammonium salts with arylalkyl and diarylalkyl substitution and their antiprotozoal activity. Monatsh Chem. 2024;155:73-81. DOI: 10.1007/s00706-023-03142-8

Taylor A.E, Hering M, Elsegood M.R.J, Teat S.J, Weaver G.W, Arroo R.R.J, Kaiser M, Mäser P, Bhambra A.S. Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against T.brucei. Bioorg Med Chem Lett. 2024;109:129825. DOI: 10.1016/j.bmcl.2024.129825

Trometer N, Pecourneau J, Feng L, Navarro-Huerta J.A, Lazarin-Bidóia D, de Oliveira Silva Lautenschlager S, Maes L, Fortes Francisco A, Kelly J.M, Meunier B, Cal M, Mäser P, Kaiser M, Davioud-Charvet E. Synthesis and anti-Chagas activity profile of a redox-active Lead 3-benzylmenadione revealed by high-content imaging. ACS Infect Dis. 2024;10(5):1808-1838. DOI: 10.1021/acsinfecdis.4c00137

Vahekeni N, Brillatz T, Rahmaty M, Cal M, Keller-Märki S, Rocchetti R, Kaiser M, Sax S, Mattli K, Wolfram E, Marcourt L, Queiroz E.F, Wolfender J.L, Mäser P. Antiprotozoal activity of plants used in the management of sleeping sickness in Angola and bioactivity-guided fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. active against T. b rhodesiense. Molecules. 2024;29(7):1611. DOI: 10.3390/molecules29071611

Walesch S, Garcia R, Mahmoud A.B, Panter F, Bollenbach S, Mäser P, Kaiser M, Krug D, Müller R. New myxobacteria of the Myxococcaceae clade produce angiolams with antiparasitic activities. Microbiol Spectr. 2024;12(3):e0368923. DOI: 10.1128/spectrum.03689-23

Walz A, Lehmann U, Duthaler U, Mäser P, Wittlin S. In vivo antimalarial efficacy of Artemisia afra powder suspensions. Phytomedicine. 2024;129:155644. DOI: 10.1016/j.phymed.2024.155644

Walz A, Sax S, Scheurer C, Tamasi B, Mäser P, Wittlin S. Incomplete Plasmodium falciparum growth inhibition following piperaquine treatment translates into increased parasite viability in the in vitro parasite reduction ratio assay. Front Cell Infect Microbiol. 2024;14:1396786. DOI: 10.3389/fcimb.2024.1396786

Albisetti A, Hälg S, Zoltner M, Mäser P, Wiedemar N. Suramin action in African trypanosomes involves a RuvB-like DNA helicase. Int J Parasitol Drugs Drug Resist. 2023;23:44-53. DOI: 10.1016/j.ijpddr.2023.09.003

Fesser A, Beilstein S, Kaiser M, Schmidt R.S, Mäser P. Trypanosoma cruzi STIB980: a TcI strain for drug discovery and reverse genetics. Pathogens. 2023;12(10):1217. DOI: 10.3390/pathogens12101217

Hinteregger C, Dolensky J, Seebacher W, Saf R, Mäser P, Kaiser M, Weis R. Synthesis and antiprotozoal activity of azabicyclo-nonane pyrimidine hybrids. Molecules. 2023;28:307. DOI: 10.3390/molecules28010307

Hochegger P, Hermann T, Dolensky J, Seebacher W, Saf R, Pferschy-Wenzig E.M, Kaiser M, Mäser P, Weis R. Structure-activity relationships and antiplasmodial potencies of novel 3,4-disubstituted 1,2,5-oxadiazoles. Int J Mol Sci. 2023;24(19):14480. DOI: 10.3390/ijms241914480

Mäser P, Bernhard S, Brun R, Burri C, Gagneux S, Hetzel M.W, Kaiser M, Lengeler C, Pluschke G, Reus E, Rottmann M, Utzinger J, Warryn L, Wittlin S, Keiser J. Key contributions by the Swiss Tropical and Public Health Institute towards new and better drugs for tropical diseases. Chimia (Aarau). 2023;77(9):593-606. DOI: 10.2533/chimia.2023.593

Meier L, Antillón M, Burri C, Chitnis N, Endriss Y, Keiser J, Moore S, Müller P, Penny M, Voss T.S, Mäser P, Utzinger J. Repurposing know-how for drug development: case studies from the Swiss Tropical and Public Health Institute. Chimia (Aarau). 2023;77(9):582-592. DOI: 10.2533/chimia.2023.582

Rao S.P.S, Gould M.K, Noeske J, Saldivia M, Jumani R.S, Ng P.S, Rene O, Chen Y.L, Kaiser M, Ritchie R, Francisco A.F, Johnson N, Patra D, Cheung H, Deniston C, Schenk A.D, Cortopassi W.A, Schmidt R.S, Wiedemar N, Thomas B, Palkar R, Ghafar N.A, Manoharan V, Luu C, Gable J.E, Wan K.F, Myburgh E, Mottram J.C, Barnes W, Walker J, Wartchow C, Aziz N, Osborne C, Wagner J, Sarko C, Kelly J.M, Manjunatha U.H, Mäser P, Jiricek J, Lakshminarayana S.B, Barrett M.P, Diagana T.T. Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections. Science. 2023;380(6652):1349-1356. DOI: 10.1126/science.adh0614

Seebacher W, Kaiser M, Mäser P, Saf R, Pferschy-Wenzig E.M, Weis R. Benzyl- and dibenzyl tetrahydropyridinylidene ammonium salts with antiplasmodial and antitrypanosomal activity. Monatsh Chem. 2023;154:105-114. DOI: 10.1007/s00706-022-03003-w

Sevik Kilicaslan O, Cretton S, Hausmann E, Quirós-Guerrero L, Karimou S, Kaiser M, Mäser P, Christen P, Cuendet M. Antiprotozoal activity of natural products from Nigerien plants used in folk medicine. Front Pharmacol. 2023;14:1190241. DOI: 10.3389/fphar.2023.1190241

Utzinger J,Mäser P, eds. Swiss TPH: 30 years of R&D towards new drugs for tropical diseases. 77. Special issue, 2023. DOI: 10.2533/chimia.2023.570

Walz A, Duffey M, Aljayyoussi G, Sax S, Leroy D, Besson A, Burrows J.N, Cherkaoui-Rbati M.H, Gobeau N, Westwood M-A, Siethoff C, Gamo S, Mäser P, Wittlin S. The Parasite Reduction Ratio (PRR) assay version 2: standardized assessment of Plasmodium falciparum viability after antimalarial treatment in vitro. Pharmaceuticals (Basel). 2023;16(2):163. DOI: 10.3390/ph16020163

Beilstein S, El Phil R, Sahraoui S.S, Scapozza L, Kaiser M, Mäser P. Laboratory selection of trypanosomatid pathogens for drug resistance. Pharmaceuticals (Basel). 2022;15(2):135. DOI: 10.3390/ph15020135

Bernhard S, Kaiser M, Burri C, Mäser P. Fexinidazole for human African trypanosomiasis, the fruit of a successful public-private partnership. Diseases. 2022;10(4):90. DOI: 10.3390/diseases10040090

Dolensky J, Hinteregger C, Leitner A, Seebacher W, Saf R, Belaj F, Mäser P, Kaiser M, Weis R. Antiprotozoal activity of azabicyclo-nonanes linked to tetrazole or sulfonamide cores. Molecules. 2022;27(19):6217. DOI: 10.3390/molecules27196217

Hermann T, Wallner R, Dolensky J, Seebacher W, Pferschy-Wenzig E.-M, Kaiser M, Mäser P, Weis R. New derivatives of the multi-stage active Malaria Box compound MMV030666 and their antiplasmodial potencies. Pharmaceuticals (Basel). 2022;15(12):1503. DOI: 10.3390/ph15121503

Koester D.C, Marx V.M, Williams S, Jiricek J, Dauphinais M, René O, Miller S.L, Zhang L, Patra D, Chen Y.L, Cheung H, Gable J, Lakshminarayana S.B, Osborne C, Galarneau J.R, Kulkarni U, Richmond W, Bretz A, Xiao L, Supek F, Wiesmann C, Honnappa S, Be C, Mäser P, Kaiser M, Ritchie R, Barrett M.P, Diagana T.T, Sarko C, Rao S.P.S. Discovery of novel quinoline-based proteasome inhibitors for human African trypanosomiasis (HAT). J Med Chem. 2022;65:11776−11787. DOI: 10.1021/acs.jmedchem.2c00791

Mäser P. Filariae as organisms. In: Kaminsky R,Geary T,Selter P, eds. Human and animal filariases: landscape, challenges, and control, 17-32: Wiley, 2022

Mousavi A, Foroumadi P, Emamgholipour Z, Mäser P, Kaiser M, Foroumadi A. 2-(Nitroaryl)-5-substituted-1,3,4-thiadiazole derivatives with antiprotozoal activities: in vitro and in vivo study. Molecules. 2022;27:5559. DOI: 10.3390/molecules27175559

Scheiber N, Blaser G, Pferschy-Wenzig E.M, Kaiser M, Mäser P, Presser A. Efficient oxidative dearomatisations of substituted phenols using hypervalent iodine (iii) reagents and antiprotozoal evaluation of the resulting cyclohexadienones against T. b. rhodesiense and P. falciparum strain NF54. Molecules. 2022;27(19):6559. DOI: 10.3390/molecules27196559

Sevik Kilicaslan O, Cretton S, Quiros-Guerrero L, Bella M.A, Kaiser M, Mäser P, Ndongo J.T, Cuendet M. Isolation and structural elucidation of compounds from Pleiocarpa bicarpellata and their in vitro antiprotozoal activity. Molecules. 2022;27(7):2200. DOI: 10.3390/molecules27072200

Barth-Jaeggi T, Mäser P. Leishmaniasis in Europe and Central Asia: epidemiology, impact of habitat and lifestyle changes, HIV coinfection. In: Steinmann P,Utzinger J, eds. Neglected tropical diseases - Europe and Central Asia, 83-100. Cham: Springer, 2021. DOI: 10.1007/978-3-030-84224-6_5

Boberg M, Cal M, Kaiser M, Jansson-Lofmark R, Mäser P, Ashton M. Enantiospecific antitrypanosomal in vitro activity of eflornithine. PLoS Negl Trop Dis. 2021;15(7):e0009583. DOI: 10.1371/journal.pntd.0009583

Brand M, Wang L, Agnello S, Gazzola S, Gall F.M, Raguz L, Kaiser M, Schmidt R.S, Ritschl A, Jelk J, Hemphill A, Mäser P, Butikofer P, Adams M, Riedl R. Antiprotozoal structure-activity relationships of synthetic leucinostatin derivatives and elucidation of their mode of action. Angew Chem Int Ed Engl. 2021;60(28):15613-15621. DOI: 10.1002/anie.202102153

Cretton S, Genta-Jouve G, Kaiser M, Mäser P, Muñoz O, Bürgi T, Cuendet M, Christen P. Hygroline derivatives from Schizanthus tricolor and their anti-trypanosomatid and antiplasmodial activities. Phytochemistry. 2021;192:112957. DOI: 10.1016/j.phytochem.2021.112957

Fesser A, Kaiser M, Mäser P. Neue Parameter für die Wirkstofftestung gegen Trypanosoma cruzi. Biospektrum (Heidelb). 2021;27(2):168-170. DOI: 10.1007/s12268-021-1554-z

Flittner D, Kaiser M, Mäser P, Lopes N.P, Schmidt T.J. The alkaloid-enriched fraction of Pachysandra terminalis (Buxaceae) shows prominent activity against Trypanosoma brucei rhodesiense. Molecules. 2021;26(3):591. DOI: 10.3390/molecules26030591

Greve H.L, Kaiser M, Mäser P, Schmidt T.J. Boswellic acids show in vitro activity against Leishmania donovani. Molecules. 2021;26(12):3651. DOI: 10.3390/molecules26123651

Hermann T, Hochegger P, Dolensky J, Seebacher W, Pferschy-Wenzig E.M, Saf R, Kaiser M, Mäser P, Weis R. Synthesis and structure-activity relationships of new 2-phenoxybenzamides with antiplasmodial activity. Pharmaceuticals (Basel). 2021;14:1109. DOI: 10.3390/ph14111109

Hermann T, Hochegger P, Dolensky J, Seebacher W, Saf R, Kaiser M, Mäser P, Weis R. New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities. Pharmaceuticals (Basel). 2021;14(5):412. DOI: 10.3390/ph14050412

Hitz E, Wiedemar N, Passecker A, Graça B.A.S, Scheurer C, Wittlin S, Brancucci N.M.B, Vakonakis I, Mäser P, Voss T.S. The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites. PLoS Biol. 2021;19(12):e3001483. DOI: 10.1371/journal.pbio.3001483

Hochegger P, Dolensky J, Seebacher W, Saf R, Kaiser M, Mäser P, Weis R. 8-amino-6-methoxyquinoline-tetrazole hybrids: Impact of linkers on antiplasmodial activity. Molecules. 2021;26(18):5530. DOI: 10.3390/molecules26185530

Hoffelner M.H, Seebacher W, Kaiser M, Mäser P, Pferschy-Wenzig E.M, Saf R, Belaj F, Kretschmer N, Alajlani M, Brantner A, Bauer R, Weis R. Unexpected ring‑opening of 2,3‑dihydropyridines. Monatsh Chem. 2021;152:1347–1359. DOI: 10.1007/s00706-021-02847-y

Llurba Montesino N, Kaiser M, Mäser P, Schmidt T.J. Nucleic acid amplification techniques for the detection of Schistosoma mansoni infection in humans and the intermediate snail host: a structured review and meta-analysis of diagnostic accuracy. Molecules. 2021;26(11):3226. DOI: 10.3390/molecules26113226

Mahmoud A.B, Abd Algaffar S, van de Sande W, Khalid S, Kaiser M, Mäser P. Niclosamide is active in vitro against mycetoma pathogens. Molecules. 2021;26(13):4005. DOI: 10.3390/molecules26134005

Petritsch M, Seebacher W, Mohsin N.U, Dolensky J, Hochegger P, Kaiser M, Mäser P, Belaj F, Saf R, Kretschmer N, Alajlani M, Brantner A, Bauer R, Schuhly W, Weis R. Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. Eur J Med Chem. 2021;210:112969. DOI: 10.1016/j.ejmech.2020.112969

Rocha-Hasler M, de Oliveira G.M, da Gama A.N, Fiuza L.F.A, Fesser A.F, Cal M, Rocchetti R, Peres R.B, Guan X.L, Kaiser M, Soeiro M.N.C, Mäser P. Combination with tomatidine improves the potency of posaconazole against Trypanosoma cruzi. Front Cell Infect Microbiol. 2021;11:617917. DOI: 10.3389/fcimb.2021.617917

Seebacher W, Mohsin N.U.A, Dolensky J, Hochegger P, Kaiser M, Mäser P, Saf R, Schuster D, Temml V, Weis R. Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies. Monatsh Chem. 2021;152:1347–1359. DOI: 10.1007/s00706-021-02847-y

Szabó L.U, Kaiser M, Mäser P, Schmidt T.J. Antiprotozoal Nor-triterpene alkaloids from Buxus sempervirens L. Antibiotics (Basel). 2021;10(6):696. DOI: 10.3390/antibiotics10060696

Szabó L.U, Kaiser M, Mäser P, Schmidt T.J. Identification of antiprotozoal compounds from Buxus sempervirens L. by PLS-prediction. Molecules. 2021;26(20):6181. DOI: 10.3390/molecules26206181

Wittlin S, Mäser P. From magic bullet to magic bomb: reductive bioactivation of antiparasitic agents. ACS Infect Dis. 2021;7(10):2777-2786. DOI: 10.1021/acsinfecdis.1c00118

Zeelen J, van Straaten M, Verdi J, Hempelmann A, Hashemi H, Perez K, Jeffrey P.D, Hälg S, Wiedemar N, Mäser P, Papavasiliou F.N, Stebbins C.E. Structure of trypanosome coat protein VSGsur and function in suramin resistance. Nat Microbiol. 2021;6(3):392-400. DOI: 10.1038/s41564-020-00844-1

Cretton S, Kaiser M, Karimou S, Ebrahimi S.N, Mäser P, Cuendet M, Christen P. Pyridine-4(1H)-one alkaloids from Waltheria indica as antitrypanosomatid agents. J Nat Prod. 2020;83(11):3363-3371. DOI: 10.1021/acs.jnatprod.0c00671

Dawidowski M, Kalel V.C, Napolitano V, Fino R, Schorpp K, Emmanouilidis L, Lenhart D, Ostertag M, Kaiser M, Kolonko M, Tippler B, Schliebs W, Dubin G, Mäser P, Tetko I.V, Hadian K, Plettenburg O, Erdmann R, Sattler M, Popowicz G.M. Structure-activity relationship in pyrazolo[4,3-c]pyridines, first inhibitors of PEX14-PEX5 protein-protein interaction with trypanocidal activity. J Med Chem. 2020;63(2):847-879. DOI: 10.1021/acs.jmedchem.9b01876

Dickie E.A, Giordani F, Gould M.K, Mäser P, Burri C, Mottram J.C, Rao S.P.S, Barrett M.P. New drugs for human African trypanosomiasis: a twenty first century success story. Trop Med Infect Dis. 2020;5:29. DOI: 10.3390/tropicalmed5010029

Fesser A.F, Braissant O, Olmo F, Kelly J.M, Mäser P, Kaiser M. Non-invasive monitoring of drug action: a new live in vitro assay design for Chagas' disease drug discovery. PLoS Negl Trop Dis. 2020;14(7):e0008487. DOI: 10.1371/journal.pntd.0008487

Hoffelner M, Hassan U, Seebacher W, Dolensky J, Hochegger P, Kaiser M, Mäser P, Saf R, Weis R. New 2‑aminopyrimidine derivatives and their antitrypanosomal and antiplasmodial activities. Monatsh Chem. 2020;151:1375–1385

Kaiser M, Mäser P. In vitro drug efficacy testing against Trypanosoma brucei. In: Michels P.A.M,Ginger M.L,Zilberstein D, eds. Trypanosomatids: methods and protocols. 2116, 781-789. New York: Springer, 2020. DOI: 10.1007/978-1-0716-0294-2_46

Mahmoud A.B, Danton O, Kaiser M, Han S, Moreno A, Abd Algaffar S, Khalid S, Oh W.K, Hamburger M, Mäser P. Lignans, amides, and saponins from Haplophyllum tuberculatum and their antiprotozoal activity. Molecules. 2020;25(12):2825. DOI: 10.3390/molecules25122825

Mahmoud A.B, Danton O, Kaiser M, Khalid S, Hamburger M, Mäser P. HPLC-based activity profiling for antiprotozoal compounds in Croton gratissimus and Cuscuta hyalina. Front Pharmacol. 2020;11:1246. DOI: 10.3389/fphar.2020.01246

Mahmoud A.B, Mäser P, Kaiser M, Hamburger M, Khalid S. Mining Sudanese medicinal plants for antiprotozoal agents. Front Pharmacol. 2020;11:865. DOI: 10.3389/fphar.2020.00865

Rao S.P.S, Lakshminarayana S.B, Jiricek J, Kaiser M, Ritchie R, Myburgh E, Supek F, Tuntland T, Nagle A, Molteni V, Mäser P, Mottram J.C, Barrett M.P, Diagana T.T. Anti-trypanosomal proteasome inhibitors cure hemolymphatic and meningoencephalic murine infection models of African trypanosomiasis. Trop Med Infect Dis. 2020;5:28. DOI: 10.3390/tropicalmed5010028

Vahekeni N, Neto P.M, Kayimbo M.K, Mäser P, Theophile J, da Costa E, Falquet J, van Eeuwijk P. Use of herbal remedies in the management of sleeping sickness in four northern provinces of Angola. J Ethnopharmacol. 2020;256:112382. DOI: 10.1016/j.jep.2019.112382

Wiedemar N, Hauser D.A, Mäser P. One hundred years of Suramin. Antimicrob Agents Chemother. 2020;64(3):e01168-19. DOI: 10.1128/AAC.01168-19

Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig J.A, Pisco J.P, Peet C, Dranow D.M, Robinson D.A, Jansen C, Norcross N.R, Vinayak S, Anderson M, Brooks C.F, Cooper C.A, Damerow S, Delves M, Dowers K, Duffy J, Edwards T.E, Hallyburton I, Horst B.G, Hulverson M.A, Ferguson L, Jiménez-Díaz M.B, Jumani R.S, Lorimer D.D, Love M.S, Maher S, Matthews H, McNamara C.W, Miller P, O'Neill S, Ojo K.K, Osuna-Cabello M, Pinto E, Post J, Riley J, Rottmann M, Sanz L.M, Scullion P, Sharma A, Shepherd S.M, Shishikura Y, Simeons F.R.C, Stebbins E.E, Stojanovski L, Straschil U, Tamaki F.K, Tamjar J, Torrie L.S, Vantaux A, Witkowski B, Wittlin S, Yogavel M, Zuccotto F, Angulo-Barturen I, Sinden R, Baum J, Gamo F.J, Mäser P, Kyle D.E, Winzeler E.A, Myler P.J, Wyatt P.G, Floyd D, Matthews D, Sharma A, Striepen B, Huston C.D, Gray D.W, Fairlamb A.H, Pisliakov A.V, Walpole C, Read K.D, Van Voorhis W.C, Gilbert I.H. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proc Natl Acad Sci USA. 2019;116(14):7015-7020. DOI: 10.1073/pnas.1814685116

Hochegger P, Faist J, Seebacher W, Saf R, Mäser P, Kaiser M, Weis R. Synthesis and structure-activity relationships for new 6-fluoroquinoline derivatives with antiplasmodial activity. Bioorg Med Chem. 2019;27(10):2052-2065. DOI: 10.1016/j.bmc.2019.03.061

Hochegger P, Faist J, Seebacher W, Saf R, Mäser P, Kaiser M, Weis R. Antiprotozoal activities of tetrazole-quinolines with aminopiperidine linker. Med Chem. 2019;15(4):409-416. DOI: 10.2174/1573406414666181015115101

Hoffelner M, Petritsch M, Ahmad S, Seebacher W, Dolensky J, Hochegger P, Kaiser M, Mäser P, Saf R, Weis R. New derivatives of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities. Monatsh Chem. 2019;150(11):1959-1972. DOI: 10.1007/s00706-019-02509-0

Jourdan J, Walz A, Matile H, Schmidt A, Wu J, Wang X, Dong Y, Vennerstrom J.L, Schmidt R.S, Wittlin S, Mäser P. Stochastic protein alkylation by antimalarial peroxides. ACS Infect Dis. 2019;5(12):2067-2075. DOI: 10.1021/acsinfecdis.9b00264

Mäser P. Parasiten machen Geschichte. In: Bregy C,Buschle M,Settelen-Trees D, eds. Gespräche im Garten: Kultur - Natur - Gutes Leben: , 127-131. Basel: Christoph Merian Verlag, 2019

Mohsin N.U.A, Seebacher W, Hochegger P, Faist J, Saf R, Kaiser M, Mäser P, Weis R. Synthesis of new 1-benzyl tetrahydropyridin-4-ylidene piperidinium salts and their antiplasmodial and antitrypanosomal activities. Med Chem Res. 2019;28(5):742-753. DOI: 10.1007/s00044-019-02331-7

Rao S.P.S, Barrett M.P, Dranoff G, Faraday C.J, Gimpelewicz C.R, Hailu A, Jones C.L, Kelly J.M, Lazdins-Helds J.K, Mäser P, Mengel J, Mottram J.C, Mowbray C.E, Sacks D.L, Scott P, Spath G.F, Tarleton R.L, Spector J.M, Diagana T.T. Drug discovery for kinetoplastid diseases: future directions. ACS Infect Dis. 2019;5(2):152-157. DOI: 10.1021/acsinfecdis.8b00298

Saccoliti F, Madia V.N, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet Alvarez C.M, Jennings G.K, Podust L.M, Pepe G, Cirilli R, Faggi C, Di Marco A, Battista M.R, Summa V, Costi R, Di Santo R. Design, synthesis, and biological evaluation of new 1-(Aryl-1H-pyrrolyl)(phenyl)methyl-1H-imidazole derivatives as antiprotozoal agents. J Med Chem. 2019;62(3):1330-1347. DOI: 10.1021/acs.jmedchem.8b01464

Walz A, Leroy D, Andenmatten N, Mäser P, Wittlin S. Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay. Malar J. 2019;18:427. DOI: 10.1186/s12936-019-3056-8

Wiedemar N, Zwyer M, Zoltner M, Cal M, Field M.C, Mäser P. Expression of a specific variant surface glycoprotein has a major impact on suramin sensitivity and endocytosis in Trypanosoma brucei. FASEB Bioadv. 2019;1(10):595-608. DOI: 10.1096/fba.2019-00033

Grogg M, Hilvert D, Ebert M.O, Beck A.K, Seebach D, Kurth F, Dittrich P.S, Sparr C, Wittlin S, Rottmann M, Mäser P. Cell penetration, herbicidal activity, and in-vivo-toxicity of oligo-arginine derivatives and of novel guanidinium-rich compounds derived from the biopolymer cyanophycin. Helvetica Chimica Acta. 2018;101(10):e1800112. DOI: 10.1002/hlca.201800112

Gysin M, Braissant O, Gillingwater K, Brun R, Mäser P, Wenzler T. Isothermal microcalorimetry – a quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time. Int J Parasitol Drugs Drug Resist. 2018;8(2):159-164. DOI: 10.1016/j.ijpddr.2018.03.003

Kalel V.C, Mäser P, Sattler M, Erdmann R, Popowicz G.M. Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development. Curr Opin Microbiol. 2018;46:116-122. DOI: 10.1016/j.mib.2018.11.003

Mäser P. Host-Microbe Interactions: Parasitology Vol 46. Curr Opin Microbiol. 2018;46:vi-viii. DOI: 10.1016/j.mib.2018.11.008

Mohsin N.U.A, Seebacher W, Faist J, Hochegger P, Kaiser M, Mäser P, Belaj F, Saf R, Kretschmer N, Alajlani M, Turek I, Brantner A, Bauer R, Bucar F, Weis R. Synthesis of new 1-benzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. Eur J Med Chem. 2018;143:97-106. DOI: 10.1016/j.ejmech.2017.11.025

Mohsin N.U.A, Seebacher W, Faist J, Hochegger P, Kaiser M, Mäser P, Saf R, Weis R. The antiplasmodial and antitrypanosomal activities of novel piperazine derivatives of 3-azabicyclo[3.2.2]nonanes. Monatsh Chem. 2018;149(1):99-109. DOI: 10.1007/s00706-017-2109-3

Mohsin N.U.A, Seebacher W, Faist J, Kretschmer N, Bauer R, Saf R, Kaiser M, Mäser P, Weis R. Modifications on tetrahydropyridin-4-ylidene ammonium salts and their antiprotozoal activities. Monatsh Chem. 2018;149(4):801-812. DOI: 10.1007/s00706-017-2111-9

Oufir M, Gillingwater K, Hamburger M, Roditi I, Brun R, Mäser P, Wenzler T. Pharmacokinetic profiles reconcile in vitro and in vivo activities of novel trypanocidal compounds. Matters. 2018;Aug 14th:07000009. DOI: 10.19185/matters.201807000009

Saccoliti F, Madia V.N, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P. Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents. Eur J Med Chem. 2018;156:53-60. DOI: 10.1016/j.ejmech.2018.06.063

Schmidt R.S, Macedo J.P, Steinmann M.E, Salgado A.G, Butikofer P, Sigel E, Rentsch D, Mäser P. Transporters of Trypanosoma brucei: phylogeny, physiology, pharmacology. FEBS J. 2018;285(6):1012-1023. DOI: 10.1111/febs.14302

Subramaniam S, Schmid C.D, Guan X.L, Mäser P. Using yeast synthetic lethality to inform drug combination for malaria. Antimicrob Agents Chemother. 2018;62(4):e01533-17. DOI: 10.1128/AAC.01533-17

Wiedemar N, Graf F.E, Zwyer M, Ndomba E, Kunz Renggli C, Cal M, Schmidt R.S, Wenzler T, Mäser P. Beyond immune escape: a variant surface glycoprotein causes suramin resistance in Trypanosoma brucei. Mol Microbiol. 2018;107(1):57-67. DOI: 10.1111/mmi.13854

Baumgärtner F, Jourdan J, Scheurer C, Blasco B, Campo B, Mäser P, Wittlin S. In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate. Malar J. 2017;16:45. DOI: 10.1186/s12936-017-1696-0

Dawidowski M, Emmanouilidis L, Kalel V.C, Tripsianes K, Schorpp K, Hadian K, Kaiser M, Mäser P, Kolonko M, Tanghe S, Rodriguez A, Schliebs W, Erdmann R, Sattler M, Popowicz G.M. Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites. Science. 2017;355(6332):1416-1420. DOI: 10.1126/science.aal1807

Faist J, Hinteregger C, Seebacher W, Saf R, Mäser P, Kaiser M, Weis R. New derivatives of 7-chloroquinolin-4-amine with antiprotozoal activity. Bioorg Med Chem. 2017;25(3):941-948. DOI: 10.1016/j.bmc.2016.12.006

Guan X.L, Mäser P. Comparative sphingolipidomics of disease-causing trypanosomatids reveal unique lifecycle- and taxonomy-specific lipid chemistries. Sci Rep. 2017;7:13617. DOI: 10.1038/s41598-017-13931-x

Hochegger P, Faist J, Seebacher W, Saf R, Mäser P, Kaiser M, Weis R. New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity. Bioorg Med Chem. 2017;25(7):2251-2259. DOI: 10.1016/j.bmc.2017.02.043

Jeacock L, Baker N, Wiedemar N, Mäser P, Horn D. Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity. PLoS Pathog. 2017;13(3):e1006307. DOI: 10.1371/journal.ppat.1006307

Mäser P. Cherchez l'electron. Mol Microbiol. 2017;106(2):183-185. DOI: 10.1111/mmi.13773

Mathieu C, Macedo J.P, Hürlimann D, Wirdnam C, Haindrich A.C, Suter Grotemeyer M, Gonzalez-Salgado A, Schmidt R.S, Inbar E, Mäser P, Butikofer P, Zilberstein D, Rentsch D. Arginine and lysine transporters are essential for Trypanosoma brucei. PLoS One. 2017;12(1):e0168775. DOI: 10.1371/journal.pone.0168775

Seebacher W, Belaj F, Faist J, Saf R, Bucar F, Turek I, Brantner A, Alajlani M, Kaiser M, Mäser P, Weis R. Synthesis of new pyrido-benzodiazepine salts and their antimicrobial activities. Monatsh Chem. 2017;148(2):263-274. DOI: 10.1007/s00706-016-1864-x

Steinmann M.E, Schmidt R.S, Bütikofer P, Mäser P, Sigel E. TbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes. Sci Rep. 2017;7(1):656. DOI: 10.1038/s41598-017-00752-1

Steinmann M.E, Schmidt R.S, Macedo J.P, Kunz Renggli C, Bütikofer P, Rentsch D, Mäser P, Sigel E. Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. PLoS One. 2017;12(12):e0188219. DOI: 10.1371/journal.pone.0188219

Graf F.E, Ludin P, Arquint C, Schmidt R.S, Schaub N, Kunz-Renggli C, Krezdorn J, Baker N, Horn D, Balmer O, Caccone A, de Koning H.P, Mäser P, Munday J.C. Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense. Cell Mol Life Sci. 2016;37(17):3387. DOI: 10.1007/s00018-016-2173-6

Jourdan J, Matile H, Reift E, Biehlmaier O, Dong Y, Wang X, Mäser P, Vennerstrom J.L, Wittlin S. Monoclonal antibodies that recognize the alkylation signature of antimalarial ozonides OZ277 (Arterolane) and OZ439 (Artefenomel). ACS Infect Dis. 2016;2:54-61. DOI: 10.1021/acsinfecdis.5b00090

Mäser P, Brun R. From molecule to drug. In: Walochnik J,Duchêne M, eds. Molecular parasitology: protozoan parasites and their molecules, 491-507. Wien: Springer, 2016. DOI: 10.1007/978-3-7091-1416-2_15

Wang T, Mäser P, Picard D. Inhibition of Plasmodium falciparum Hsp90 contributes to the antimalarial activities of aminoalcohol-carbazoles. J Med Chem. 2016;59(13):6344-6352. DOI: 10.1021/acs.jmedchem.6b00591

Wenzler T, Schumann Burkard G, Schmidt R.S, Mäser P, Bergner A, Roditi I, Brun R. A new approach to chemotherapy: drug-induced differentiation kills African trypanosomes. Sci Rep. 2016;6:22451. DOI: 10.1038/srep22451

Beer D, Barret M, Begolo D, Clayton C, Jiricek J, Kaiser M, Koh H, Kounde C, Lakshminarayana S, Manoharan V, Mottram J, Myburgh E, Ng P, Rao S, Schirle M, Tania S, Thomas J, Vachaspati P, Vincent I, Wipfeli P, Wong J, Mäser P, Diagana T. Cell-based drug discovery model at the Novartis Institute for Tropical Diseases using Human African Trypanosomiasis as an example. Trop Med Int Health, 2015;20(Suppl. 1):125. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Cal M, Ioset J.R, Fügi M, Mäser P, Kaiser M. An in vitro assay to assess antichagasic candidates for sterile cure. Trop Med Int Health, 2015;20(Suppl. 1):335. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

de Macedo J.P, Schumann Burkard G, Niemann M, Barrett M.P, Vial H, Mäser P, Roditi I, Schneider A, Bütikofer P. An atypical mitochondrial carrier that mediates drug action in Trypanosoma brucei. PLoS Pathog. 2015;11(5):e1004875. DOI: 10.1371/journal.ppat.1004875

Fesser A.F, Schmidt R.S, Mäser P, Cal M, Kaiser M. Stage-specific reporter gene expression in Trypanosoma cruzi. Trop Med Int Health, 2015;20(Suppl. 1):339. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Fügi M.A, Kaiser M, Tanner M, Schneiter R, Mäser P, Guan X.L. Match-making for pasaconazole through systems thinking. Trends Parasitol. 2015;31(2):46-51. DOI: 10.1016/j.pt.2014.11.004

Graf F.E, Baker N, Munday J.C, de Koning H.P, Horn D, Mäser P. Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical Trypanosoma brucei gambiense isolates. Int J Parasitol Drugs Drug Resist. 2015;5(2):65-68. DOI: 10.1016/j.ijpddr.2015.04.002

Jourdan J, Matile H, Vennerstrom J.L, Mäser P, Wittlin S. Mode of action of antimalarial peroxides. Trop Med Int Health, 2015;20(Suppl. 1):183. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Kaiser M, Mäser P, Tadoori L.P, Ioset J.R, Brun R. Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning. PLoS One. 2015;10(8):e0135556. DOI: 10.1371/journal.pone.0135556

Shameer S, Logan-Klumpler F.J, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach A.M, Bannerman-Chukualim B, Creek D.J, Crouch K, de Koning H.P, Denise H, Ebikeme C, Fairlamb A.H, Ferguson M.A, Ginger M.L, Hertz-Fowler C, Kerkhoven E.J, Mäser P, Michels P.A, Nayak A, Nes D.W, Nolan D.P, Olsen C, Silva-Franco F, Smith T.K, Taylor M.C, Tielens A.G, Urbaniak M.D, van Hellemond J.J, Vincent I.M, Wilkinson S.R, Wyllie S, Opperdoes F.R, Barrett M.P, Jourdan F. TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. Nucleic Acids Res. 2015;43(D1):D637-D644. DOI: 10.1093/nar/gku944

Steinmann M.E, González-Salgado A, Bütikofer P, Mäser P, Sigel E. A heteromeric potassium channel involved in the modulation of the plasma membrane potential is essential for the survival of African trypanosomes. FASEB J. 2015;29(8):3228-3237. DOI: 10.1096/fj.15-271353

Wenzler T, Burkard G.S, Mäser P, Roditi I, Brun R. Drug-induced differentiation leads to lysis of African trypanosomes. Trop Med Int Health, 2015;20(Suppl. 1):166. Abstracts of the 9th European Congress on Tropical Medicine and International Health, 6-10 September 2015, Basel, Switzerland

Witschel M.C, Rottmann M, Schwab A, Leartsakulpanich U, Chitnumsub P, Seet M, Tonazzi S, Schwertz G, Stelzer F, Mietzner T, McNamara C, Thater F, Freymond C, Jaruwat A, Pinthong C, Riangrungroj P, Oufir M, Hamburger M, Mäser P, Sanz-Alonso L.M, Charman S, Wittlin S, Yuthavong Y, Chaiyen P, Diederich F. Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. J Med Chem. 2015;58(7):3117-3130. DOI: 10.1021/jm501987h

Fügi M.A, Gunasekera K, Ochsenreiter T, Guan X, Wenk M.R, Mäser P. Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack. J Lipid Res. 2014;55(5):929-938. DOI: 10.1194/jlr.M048017

Lüscher A, Lamprea-Burgunder E, Graf F.E, de Koning H.P, Mäser P. Trypanosoma brucei adenine-phosphoribosyltransferases mediate adenine salvage and aminopurinol susceptibility but not adenine toxicity. Int J Parasitol Drugs Drug Resist. 2014;4(1):55-63. DOI: 10.1016/j.ijpddr.2013.12.001

Mathieu C, Salgado A.G, Wirdnam C, Meier S, Grotemeyer M.S, Inbar E, Mäser P, Zilberstein D, Sigel E, Bütikofer P, Rentsch D. Trypanosoma brucei eflornithine transporter AAT6 is a low-affinity low-selective transporter for neutral amino acids. Biochem J. 2014;463(1):9-18. DOI: 10.1042/BJ20140719

Munday J.C, Eze A.A, Baker N, Glover L, Clucas C, Aguinaga Andres D, Natto M.J, Teka I.A, McDonald J, Lee R.S, Graf F.E, Ludin P, Burchmore R.J, Turner C.M, Tait A, Macleod A, Mäser P, Barrett M.P, Horn D, de Koning H.P. Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. J Antimicrob Chemother. 2014;69(3):651-663. DOI: 10.1093/jac/dkt442

Sistrom M, Evans B, Bjornson R, Gibson W, Balmer O, Mäser P, Aksoy S, Caccone A. Comparative genomics reveals multiple genetic backgrounds of human pathogenicity in the Trypanosoma brucei complex. Genome Biol Evol. 2014;6(10):2811-2819. DOI: 10.1093/gbe/evu222

Wang T, Bisson W.H, Mäser P, Scapozza L, Picard D. Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective Inhibitors. J Med Chem. 2014;57(6):2524-2535. DOI: 10.1021/jm401801t

Ali J.A.M, Creek D.J, Burgess K, Allison H.C, Field M.C, Mäser P, de Koning H.P. Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines. Mol Pharmacol. 2013;83(2):439-453. DOI: 10.1124/mol.112.082321

Baker N, de Koning H.P, Mäser P, Horn D. Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story. Trends Parasitol. 2013;29(3):110-118. DOI: 10.1016/j.pt.2012.12.005

Graf F, Ludin P, Kunz-Renggli C, de Koning H.P, Mäser P. Comparative genomics of drug resistance in African trypanosomes. Virulence, 2013;4(4):337-338

Graf F.E, Ludin P, Wenzler T, Kaiser M, Brun R, Pyana P.P, Buscher P, de Koning H.P, Horn D, Mäser P. Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol. PLoS Negl Trop Dis. 2013;7(10):e2475. DOI: 10.1371/journal.pntd.0002475

Greganova E, Steinmann M, Mäser P, Fankhauser N. In silico ionomics segregates parasitic from free-living eukaryotes. Genome Biol Evol. 2013;5(10):1902-1909. DOI: 10.1093/gbe/evt134

Macêdo J.P, Schmidt R.S, Mäser P, Rentsch D, Vial H.J, Sigel E, Butikofer P. Characterization of choline uptake in Trypanosoma brucei procyclic and bloodstream forms. Mol Biochem Parasitol. 2013;190(1):16-22. DOI: 10.1016/j.molbiopara.2013.05.007

Nickel B, Ahmarani F, Pittet A, List C, Mäser P, Marti H. Evaluation of synthetic peptides from the K39-sequence for diagnostics of visceral leishmaniasis. Trop Med Int Health, 2013;18(Suppl. 1):138

Godel C, Kumar S, Koutsovoulos G, Ludin P, Nilsson D, Comandatore F, Wrobel N, Thompson M, Schmid C.D, Goto S, Bringaud F, Wolstenholme A, Bandi C, Epe C, Kaminsky R, Blaxter M, Mäser P. The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets. FASEB J. 2012;26(11):4650-4661. DOI: 10.1096/fj.12-205096

Gonzalez-Salgado A, Steinmann M.E, Greganova E, Rauch M, Mäser P, Sigel E, Bütikofer P. myo-inositol uptake is essential for bulk inositol phospholipid but not glycosylphosphatidylinositol synthesis in Trypanosoma brucei. J Biol Chem. 2012;287(16):13313-13323. DOI: 10.1074/jbc.M112.344812

Ludin P, Woodcroft B, Ralph S.A, Mäser P. In silicio prediction of antimalarial drug target candidates. Int J Parasitol Drugs Drug Resist. 2012;2:191-199. DOI: 10.1016/j.ijpddr.2012.07.002

Mäser P, Wittlin S, Rottmann M, Wenzler T, Kaiser M, Brun R. Antiparasitic agents: new drugs on the horizon. Curr Opin Pharmacol. 2012;12(5):562-566. DOI: 10.1016/j.coph.2012.05.001

Oehring S.C, Woodcroft B.J, Moes S, Wetzel J, Dietz O, Pulfer A, Dekiwadia C, Mäser P, Flück C, Witmer K, Brancucci N.M, Niederwieser I, Jenoe P, Ralph S.A, Voss T.S. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Genome Biol. 2012;13(11):R108. DOI: 10.1186/gb-2012-13-11-r108

Lamprea-Burgunder E, Ludin P, Mäser P. Species-specific typing of DNA based on palindrome frequency patterns. DNA Res. 2011;18(2):117-124. DOI: 10.1093/dnares/dsr004

Ludin P, Nilsson D, Mäser P. Genome-wide identification of molecular mimicry candidates in parasites. PLoS One. 2011;6(3):e17546. DOI: 10.1371/journal.pone.0017546

Teka I.A, Kazibwe A.J.N, El-Sabbagh N, Al-Salabi M.I, Ward C.P, Eze A.A, Munday J.C, Mäser P, Matovu E, Barrett M.P, de Koning H.P. The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes. Mol Pharmacol. 2011;80(1):110-116. DOI: 10.1124/mol.111.071555

Mosimann M, Goshima S, Wenzler T, Luscher A, Uozumi N, Mäser P. A Trk/HKT-type K+ transporter from Trypanosoma brucei. Eukaryot Cell. 2010;9(4):539-546. DOI: 10.1128/EC.00314-09

Nerima B, Mäser P. Identification of potential drug targets in protozoan parasites using comparative genomics. Am J Trop Med Hyg, 2010;83(5 Suppl. 1):205-205

Nerima B, Nilsson D, Mäser P. Comparative genomics of metabolic networks of free-living and parasitic eukaryotes. BMC Genomics. 2010;11:217. DOI: 10.1186/1471-2164-11-217

Rufener L, Baur R, Kaminsky R, Mäser P, Sigel E. Monepantel allosterically activates DEG-3/DES-2 channels of the gastrointestinal nematode Haemonchus contortus. Mol Pharmacol. 2010;78(5):895-902. DOI: 10.1124/mol.110.066498

Rufener L, Keiser J, Kaminsky R, Mäser P, Nilsson D. Phylogenomics of ligand-gated ion channels predicts monepantel effect. PLoS Pathog. 2010;6(9):e1001091. DOI: 10.1371/journal.ppat.1001091

Kuettel S, Mosimann M, Mäser P, Kaiser M, Brun R, Scapozza L, Perozzo R. Adenosine kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics. PLoS Negl Trop Dis. 2009;3(8):e506. DOI: 10.1371/journal.pntd.0000506

Bernhard S.C, Nerima B, Mäser P, Brun R. Melarsoprol- and pentamidine-resistant Trypanosoma brucei rhodesiense populations and their cross-resistance. Int J Parasitol. 2007;37(13):1443-1448. DOI: 10.1016/j.ijpara.2007.05.007

Maina N, Maina K.J, Mäser P, Brun R. Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate. Acta Trop. 2007;104(2-3):84-90. DOI: 10.1016/j.actatropica.2007.07.007

Mäser P, Luscher A, Kaminsky R. Drug transport and drug resistance in African trypanosomes. Drug Resist Updat. 2003;6(5):281-290

Matovu E, Stewart M.L, Geiser F, Brun R, Mäser P, Wallace L.J, Burchmore R.J, Enyaru J.C, Barrett M.P, Kaminsky R, Seebeck T, Koning H.P. Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. Eukaryot Cell. 2003;2(5):1003-1008