Publications

Beynon F, Mhalu G, Kumar D, Cicconi S, Langet H, Levine G.A, Agarwal G, Festo C, Glass T.R, Jacob A, Kumar G, Lwambura S, Matata L, Mkopi A, Moshiro R, Schaer F, Bandi V, Bohle L.F, Emmanuel-Fabula M, Horlacher M, Horton S, Maiba J, Makawia S, Masanja N, Mjungu D, Mtebene I.E, Odek O, Oliveira V, Pantjushenko E, Reus E, Ruffo M, Sharma K, Storey H, Tyagi M, D'Acremont V, Masanja H, Awasthi S, Wyss K, TIMCI Collaborator Group. Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in India and Tanzania on hospitalisation and mortality: the TIMCI pragmatic cluster randomised controlled trial. EClinicalMedicine. 2025;85:103306. DOI: 10.1016/j.eclinm.2025.103306

Cobuccio L.G, Faivre V, Tan R, Vonlanthen A, Beynon F, Barchichat E, Fresco A, Girard Q, Ucak S, Schaufelberger S, Mtebene I.E, Agrea P, Kalisa E, Levine G.A, Norris M, Renggli S, Miauton A, Cleveley L, Keitel K, Thabard J, D'Acremont V, Kulinkina A.V. medAL-suite: a software solution for creating and deploying complex clinical decision support algorithms. BMC Med Inform Decis Mak. 2025;25:249. DOI: 10.1186/s12911-025-03077-6

Horton S, Adombi U, Beynon F, Emmanuel-Fabula M, Herrick T, Kumar S, Makawia S, Mugo M, Onah M, Ruffo M, Awasthi S, Ba M, Bohle L.F, Cicconi S, Langet H, Faye P.M, Masanja H, Miheso A, Mjungu D, Machoki M'Imunya J, Ndiaye O, Sharma K, D'Acremont V, Wyss K, TIMCI Collaborator Group. Costs of testing sick children in primary care with pulse oximetry: Evidence from four countries, both with and without electronic clinical decision support. PLOS Glob Public Health. 2025;5(7):e0004644. DOI: 10.1371/journal.pgph.0004644

Langet H, Faye P.M, Njiri F, Cicconi S, Levine G.A, Glass T.R, Kosgei R.J, Ngari K, Schaer F, Thiongane A, Tine J.A.D, Ba M, Bohle L.F, Emmanuel-Fabula M, Faye M.M, Horton S, Miheso A, Mugo M, Ngutu M, Ruffo M, Shauri J, Sougou N.M, D’Acremont V, Wyss K, Ndiaye O, Beynon F, The TIMCI Collaborator Group. Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in Kenya and Senegal on referral and antibiotic prescription: the TIMCI quasi-experimental pre-post study. eClinicalMedicine. 2025;83:103196. DOI: 10.1016/j.eclinm.2025.103196

Tan R, Chandna A, Colbourn T, Hooli S, King C, Lufesi N, McCollum E.D, Mwansambo C, Mathew J.L, Cutland C.L, Madhi S.A, Nunes M, Basnet S, Strand T.A, O'Grady K.F, Gessner B, Addo-Yobo E, Chisaka N, Hibberd P, Jeena P.M, Lozano J.M, MaLeod W.B, Patel A, Thea D.M, Nguyen N.T.V, Lucero M, Akram Uz Zaman S.M, Bhatnagar S, Wadhwa N, Lodha R, Aneja S, Santosham M, Awasthi S, Bavdekar A, Chou M, Nymadawa P, Pape J.W, Paranhos-Baccala G, Picot V.S, Rakoto-Andrianarivelo M, Rouzier V, Russomando G, Sylla M, Vanhems P, Wang J, Libster R, Clara A.W, Beynon F, Levine G, Rees C.A, Neuman M.I, Qazi S, Nisar Y.B, World Health Organization PREPARE study group. Development and validation of a novel clinical risk score to predict hypoxaemia in children with pneumonia using the WHO PREPARE dataset. BMJ Glob Health. 2025;10(7):e017256. DOI: 10.1136/bmjgh-2024-017256

Tyagi M, Kumar D, Sharma K, Beynon F, Kumar G, Langet H, Levine G.A, Ruffo M.A, Fabula M.E, D'Acremont V, Wyss K, Bohle L.F, Awasthi S. Barriers and enablers of using a clinical decision support algorithm to consult sick children at primary health facilities: a qualitative study from Uttar Pradesh, India. Clin Epidemiol Glob Health. 2025;34:102038. DOI: doi.org/10.1016/j.cegh.2025.102038

von Kalckreuth V, Rwandarwacu V.P, Cobuccio L, Dusengumuremyi T, Levine G.A, Norris M, Miauton A, Tan R, Rusingiza E, Umuhoza C, Rutagarama F.H, Muhire H.B, Nkuranga J.B, Vaezipour N, Keitel K, Beynon F, Tuyisenge L, D'Acremont V, Kulinkina A.V. ePOCT+ Rwanda: a clinical decision support algorithm for managing sick children below 15 years of age in primary healthcare settings. Rwanda J Med Health Sci. 2025;8(1):148-162. DOI: 10.4314/rjmhs.v8i1.13

Beynon F, Langet H, Bohle L.F, Awasthi S, Ndiaye O, Machoki M'Imunya J, Masanja H, Horton S, Ba M, Cicconi S, Emmanuel-Fabula M, Faye P.M, Glass T.R, Keitel K, Kumar D, Kumar G, Levine G.A, Matata L, Mhalu G, Miheso A, Mjungu D, Njiri F, Reus E, Ruffo M, Schär F, Sharma K, Storey H.L, Masanja I, Wyss K, D'Acremont V, TIMCI Collaborator Group. The Tools for Integrated Management of Childhood Illness (TIMCI) study protocol: a multi-country mixed-method evaluation of pulse oximetry and clinical decision support algorithms. Glob Health Action. 2024;17:2326253. DOI: 10.1080/16549716.2024.2326253

Hürlimann E, Landi M, Miikkulainen A, Renner C, Musard C, Mohamed H.H, Ali H.A, Mohamud O.S, Mohamed A.A, Salzmann T, Beynon F, Junker A. Impact of digital clinical decision support on quality of care and antibiotic stewardship for children under five in south-central Somalia. Oxf Open Digit Health. 2024;2(Suppl. 2):ii32-ii44. DOI: 10.1093/oodh/oqae029

Beynon F, Guérin F, Lampariello R, Schmitz T, Tan R, Ratanaprayul N, Tamrat T, Pellé K.G, Catho G, Keitel K, Masanja I, Rambaud-Althaus C. Digitalizing clinical guidelines: experiences in the development of clinical decision support algorithms for management of childhood illness in resource-constrained settings. Glob Health Sci Pract. 2023;11(4):e2200439. DOI: 10.9745/GHSP-D-22-00439

Beynon F, Salzmann T, Faye P.M, Thiongane A, Ndiaye O, Luwanda L.B, Alladiguimbai M, Triclin F, Harper M, Elkin J.A, Delaigue S, Tan R. Systèmes d’aide à la décision clinique pour la pédiatrie en santé. Rev Med Suisse. 2023;19(836):1398-1403. DOI: 10.53738/REVMED.2023.19.836.1398

Tan R, Cobuccio L, Beynon F, Levine G.A, Vaezipour N, Luwanda L.B, Mangu C, Vonlanthen A, De Santis O, Salim N, Manji K, Naburi H, Chirande L, Matata L, Bulongeleje M, Moshiro R, Miheso A, Arimi P, Ndiaye O, Faye M, Thiongane A, Awasthi S, Sharma K, Kumar G, Van De Maat J, Kulinkina A, Rwandarwacu V, Dusengumuremyi T, Nkuranga J.B, Rusingiza E, Tuyisenge L, Hartley M.A, Faivre V, Thabard J, Keitel K, D'Acremont V. ePOCT+ and the medAL-suite: development of an electronic clinical decision support algorithm and digital platform for pediatric outpatients in low- and middle-income countries. PLOS Digit Health. 2023;2:e0000170. DOI: 10.1371/journal.pdig.0000170

Schmitz T, Beynon F, Musard C, Kwiatkowski M, Landi M, Ishaya D, Zira J, Muazu M, Renner C, Emmanuel E, Bulus S.G, Rossi R. Effectiveness of an electronic clinical decision support system in improving the management of childhood illness in primary care in rural Nigeria: an observational study. BMJ Open. 2022;12(7):e055315. DOI: 10.1136/bmjopen-2021-055315