CR3 engaged by PGL-I triggers syk-calcineurin-NFATc to rewire the innate immune response in leprosy (Publications)
Mycobacterium leprae, the causative agent of leprosy, is unique amongst human pathogens in its capacity to produce the virulence factor phenolic glycolipid (PGL)-I. In addition to mediating bacterial
Effects of school-based physical activity and multi-micronutrient supplementation intervention on growth, health and well-being of schoolchildren in... (Publications)
BACKGROUND: In low- and middle-income countries, infectious diseases remain a key public health issue. Additionally, non-communicable diseases are a rapidly growing public health problem that impose a
The effects of medicines availability and stock-outs on household's utilization of healthcare services in Dodoma region, Tanzania (Publications)
Low- and middle-income countries have been undertaking health finance reforms to address shortages of medicines. However, data are lacking on how medicine availability and stock-outs influence access
Patterns of benzodiazepine prescription among older adults in Switzerland: a cross-sectional analysis of claims data (Publications)
OBJECTIVE: This study aimed to examine the prevalence and determinants of benzodiazepine prescription among older adults in Switzerland, and analyse association with hospitalisation and costs. DESIGN:
Rabies (Publications)
The inevitably fatal outcome of rabies makes it one of the most well-known and feared zoonoses. But rabies is still a neglected zoonotic disease (NZD), despite being one of the oldest diseases known.
Adverse cardiovascular effects of traffic noise with a focus on nighttime noise and the new WHO noise guidelines (Publications)
Exposure to traffic noise is associated with stress and sleep disturbances. The World Health Organization (WHO) recently concluded that road traffic noise increases the risk for ischemic heart disease
Burden of injuries in Vietnam: emerging trends from a decade of economic achievement (Publications)
BACKGROUND: Vietnam has been one of the fastest-growing world economies in the past decade. The burden of injuries can be affected by economic growth given the increased exposure to causes of injury a
Informed consent procedure in a double blind randomized anthelminthic trial on Pemba Island, Tanzania: do pamphlet and information session increase... (Publications)
BACKGROUND: In clinical research, obtaining informed consent from participants is an ethical and legal requirement. Conveying the information concerning the study can be done using multiple methods ye
Association of adult lung function with accelerated biological aging (Publications)
Lung function, strongly associated with morbidity and mortality, decreases with age. This study examines whether poor adult lung function is associated with age accelerations (AAs). DNA methylation (D
Clinical study on the melarsoprol-related encephalopathic syndrome: risk factors and HLA association (Publications)
Melarsoprol administration for the treatment of late-stage human African trypanosomiasis (HAT) is associated with the development of an unpredictable and badly characterized encephalopathic syndrome (