Antitrypanosomal isoflavan quinones from <em>Abrus precatorius</em> (Publications)
Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with antitrypanosomal activity, we recently id
Reactivity to accelerometer measurement of children and adolescents (Publications)
PURPOSE: Awareness of being monitored can influence participants' habitual physical activity (PA) behavior. This reactivity effect may threaten the validity of PA assessment. Reports on reactivity whe
A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalised modules for membrane antigens (GMMA) (Publications)
INTRODUCTION: Neisseria meningitidis causes epidemics of meningitis in sub-Saharan Africa. These have mainly been caused by capsular group A strains, but W and X strains are increasingly contributing
2,4-diaminothienopyrimidines as orally active antimalarial agents (Publications)
A novel series of 2,4-diaminothienopyrimidines with potential as antimalarials was identified from whole-cell high-throughput screening of a SoftFocus ion channel library. Synthesis and structure-acti
The policy of free healthcare for children under the age of 6 years in Vietnam: assessment of the uptake for children hospitalised with acute... (Publications)
OBJECTIVE: To assess the proportion of, and reasons for, households not utilising the policy of free healthcare for children under 6 years of age (FCCU6) for hospitalisation with diarrhoea, and assess
<em>In silico</em> prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against <em>Trypanosoma brucei... (Publications)
In continuation of our earlier study on the in vitro antiprotozoal activity of 40 natural sesquiterpene lactones (STLs), we extended the set of tested compounds from our laboratories to 59. On the bas
Improved services to enrollees into an HIV rural care and treatment center in Tanzania [Short communication] (Publications)
Better quality of services is essential for the sustainability of HIV programs, in particular in rural Sub-Saharan Africa, to support the increasing number of individuals treated with combination anti