Testing the feasibility, acceptability, and exploring trends on efficacy of the problem management plus for moms: protocol of a pilot randomized... (Publications)
Mental health disorders are one of the most common causes that limit the ability of mothers to care for themselves and for their children. Recent data suggest high rates of distress among women in charge [...] charge of young children in Zambia. Nevertheless, Zambia's public healthcare offers very limited treatment for common mental health distress. To address this treatment gap, this study aims to test the feasibility [...] feasibility, acceptability, and potential efficacy of a context-adapted...
IVDR: analysis of the social, economic, and practical consequences of the application of an ordinance of the <em>in vitro</em> diagnostic ordinance in... (Publications)
overall costs of the tests. The increased regulatory burden of IVDR may thereby pose an important risk for public health. Taken together, it will have a negative impact on the financial balance of diagnostic [...] range of aspects and poses a risk given the high diversity of pathogens (including rare but highly virulent microbes) and the large variety of samples submitted for analysis. The regular emergence of new [...] on production of in-house tests will negatively impact knowledge and...
Evaluation of the diagnostic performance of PanbioTM Abbott SARS-CoV-2 rapid antigen test for the detection of COVID-19 from suspects attending ALERT... (Publications)
diagnostic gaps in health institutions and community screening. However, there is no evidence or proof of diagnostic performance in Ethiopia. The aim of this study was to compare the performance of PanbioTM Abbott [...] and rapid spread of coronavirus disease 2019 (COVID-19), a potentially lethal disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is causing public health issues around the [...] standard RT-PCR. RESULT: The sensitivity and specificity of the RDT were...
Shaping the Next-generation of Interventions for Malaria Prevention (News)
https://www.swisstph.ch/de/news/news-detail-1/news/shaping-the-next-generation-of-interventions-for-malaria-prevention
Despite progress of countries in substantially reducing the number of malaria cases since 2000, malaria remains a major public health concern. In 2019, there were an estimated 229 million cases of malaria worldwide [...] populations that experience the highest burden of malaria. Need for new medical interventions Despite the potential public health value, only a small number of drugs are intended for preventative use, for [...] ed decision making between early candidate development,...
Rapid detection of the source of a Listeria monocytogenes outbreak in Switzerland through routine interviewing of patients and whole-genome sequencing (Publications)
AIMS OF THE STUDY: Listeriosis is a notifiable disease in Switzerland. In summer 2022, the Swiss Federal Office of Public Health noticed an increase in reports of listeriosis cases, indicating a possible [...] Geographically, 18 of 20 outbreak cases occurred in northeastern Switzerland. The median age of patients was 77.4 years (range: 58.1-89.7), with both sexes equally affected. Rolling analysis of the interview [...] triggering an on-site investigation of the production facility and sampling ...
Lack of antigenic diversification of major outer membrane proteins during clonal waves of <em>Neisseria meningitidis</em> serogroup A colonization and... (Publications)
In particular in the 'meningitis belt' of sub-Saharan Africa, epidemic meningococcal meningitis is a severe public health problem. In the past decades, serogroup A lineages have been the dominant etiologic [...] variation in the number of intragenic tandem repeats, showing that phase variation of Opa protein expression is a frequent event. Altogether we observed a remarkable antigenic stability of the PorA, PorB, and [...] e for the disappearance of meningococcal clones over time, it is not a...
The effects of medicines availability and stock-outs on household's utilization of healthcare services in Dodoma region, Tanzania (Publications)
promoting access to health services in low-income settings. Effective planning and medicine supply management from national to health facility level is an important component of quality health services. [...] countries have been undertaking health finance reforms to address shortages of medicines. However, data are lacking on how medicine availability and stock-outs influence access to health services in Tanzania. The [...] from households and healthcare facility surveys. A total of 4 hospitals...
Understanding context of violence against healthcare through citizen science and evaluating the effectiveness of a co-designed code of conduct and of... (Publications)
HCWs are exposed to exceptionally high rates of violence. We hypothesize that the implementation of a training on de-escalation of violence and of a code of conduct informed through participatory citizen science [...] science research would reduce the incidence and severity of episodes of violence in primary healthcare settings of rural Democratic Republic of Congo (DRC) and large hospitals in Baghdad, Iraq. METHODS: [...] transdisciplinary citizen science approach to inform the re-adaptation of...
Care seeking and treatment of febrile children with and without danger signs of severe disease in northern Uganda: results from three household... (Publications)
sector (24%). Community health workers were used as the first source of care by 12% of the children. Approximately 38% of the children who were reported to have danger signs of severe disease requiring [...] treatment patterns for children < 5 years of age with an acute febrile illness, with or without danger signs of severe disease, in a highly malaria-endemic area of northern Uganda. Three household surveys [...] drink, and vomiting everything. Only half of the children in this study sought...
Associations between key intervention coverage and child mortality: an analysis of 241 sub-national regions of sub-Saharan Africa (Publications)
contributions of public health interventions and general improvements in socioeconomic status during this time period. Methods: We combined all available data from the Demographic and Health Survey (DHS) [...] to coverage levels of key health interventions. Whereas all socioeconomic variables considered appear to strongly predict health outcomes, the same was true only for very few health coverage indicators [...] assess the associations between child mortality and changes in the coverage of 17...
