Investigating seasonal patterns in enteric infections: a systematic review of time series methods (Publications)
al factors. Public health professionals use statistical methods and time series models to describe, compare, explain, and predict seasonal patterns. However, descriptions and estimates of seasonal features [...] research and strengthen proactive and targeted public health policies, intervention strategies, and preparedness plans to dampen the intensity and impacts of seasonal illnesses. © 2022 Cambridge University [...] purposes and how they apply time series methods. In this review, we outline...
Comparing universal kriging and land-use regression for predicting concentrations of gaseous oxides of nitrogen (NOx) for the Multi-Ethnic Study of... (Publications)
Angeles, CA. METHODS: The measurements of gaseous oxides of nitrogen (NOx) used in this study are from a "snapshot" sampling campaign that is part of the Multi-Ethnic Study of Atherosclerosis and Air Pollution [...] BACKGROUND: Epidemiological studies that assess the health effects of long-term exposure to ambient air pollution are used to inform public policy. These studies rely on exposure models that use data collected [...] winter, each with about 150 sites. The design included clusters of...
Frontiers of parasitology research in the People's Republic of China: infection, diagnosis, protection and surveillance (Publications)
ABSTRACT: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical modelling [...] modelling, monitoring, evaluation, surveillance and public health response. A comprehensive effort, involving the collaboration of 188 scientists (> 85% from P.R. China) from 48 different institutions and universities [...] control programme; (ii) updating the surveillance data of...
Effect of schistosomiasis and soil-transmitted helminth infections on physical fitness of school children in Côte d'Ivoire (Publications)
helminthiasis are important public health problems in sub-Saharan Africa causing malnutrition, anemia, and retardation of physical and cognitive development. However, the effect of these diseases on physical [...] schistosomiasis, soil-transmitted helminthiasis and physical performance of children, controlling for potential confounding of Plasmodium spp. infections and environmental parameters (i.e., ambient air [...] quadruple and quintuple species infections showed VO(2) max of 52.7, 53.1,...
Social and cultural features of cholera and shigellosis in peri-urban and rural communities of Zanzibar (Publications)
control in endemic settings. Cultural concepts of illness affect many aspects of public health. In the first step of a two-step strategy to examine determinants of cholera vaccine acceptance, this study identified [...] communities of Zanzibar. A random sample of unaffected peri-urban (n=179) and rural (n=177) adults was interviewed to study community ideas of cholera and shigellosis, considering categories of distress, [...] ABSTRACT: BACKGROUND: Responding to the high burden of cholera in...
The prevalence of syphilis infection and its associated factors in the general population of Rwanda: a national household-based survey (Publications)
Background. The prevalence of syphilis among HIV-infected people is a public health concern, but there is limited literature to describe the true burden of syphilis in resource-limited settings. We conducted [...] prevalence of syphilis. Methods. A cross-sectional survey. Participants were tested for syphilis and HIV. Factors associated with syphilis infection were identified. Results. The prevalence of syphilis was [...] Conclusions. The prevalence of syphilis was significantly higher among...
Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
zoonotic disease of considerable public health and great veterinary significance and new drugs are needed. OZ78 is a promising fasciocidal drug candidate. In order to support the development of OZ78, including [...] precise, accurate, and selective for the determination of OZ78 in sheep plasma. The method was successfully applied to the evaluation of the PK profile of OZ78 in sheep [...] C8(2) analytical column (50.0mmx2.0mm, 5mum) with a mobile phase of acetonitrile (buffer B) and 5mM ammonium...
Seroprevalence of Rift Valley fever, Q fever, and brucellosis in ruminants on the southeastern shore of Lake Chad (Publications)
Abstract The seroprevalence of Rift Valley fever (RVF), brucellosis, and Q fever among domestic ruminants on the southeastern shore of Lake Chad was studied. The study area consisted of two parts, including mainland [...] prevalence of 5.7% (95% CI 3.8-7.6), and ELISA showed 11.9% (95% CI 9.3-14.6) with a kappa value of 0.53 showing a moderate agreement between the two tests. This study confirms the presence of the three [...] diseases in the study area. More research is required to assess the...
Development of prediction models to identify hotspots of schistosomiasis in endemic regions to guide mass drug administration (Publications)
forest model predicts whether S. mansoni moderate and heavy infection prevalence will exceed a public health goal of 1% in year 5 ("intensity hotspot") with 92% sensitivity, 79% specificity, and 96% NPV, and [...] a reanalysis of randomized trials in 589 communities in five endemic countries, a regression model predicts whether Schistosoma mansoni infection prevalence will exceed the WHO threshold of 10% in year [...] Schistosomiasis is a neglected tropical disease affecting over 150 million...
Special issue "The past and present threat of rickettsial diseases" (Publications)
Historically, the rickettsioses have a track record of making substantial impact on mankind in military activities and international public health over the past centuries [...].