Shoot growth of mature Fagus sylvatica and Picea abies in relation to ozone (Publications)
growth was observed which corresponded to a 7.4% growth reduction between 0 and 10 ppm h AOT40 (accumulated ozone over threshold 40). This is in the same order of magnitude as the response observed in [...] in 83 Swiss permanent forest observation plots and of Picea abies in 61 plots was evaluated for 11 and 8 consecutive years, respectively, using branches harvested every 4 years. The data were assessed as
Shoot growth of mature Fagus sylvatica and Picea abies in relation to ozone (Publications)
growth was observed which corresponded to a 7.4% growth reduction between 0 and 10 ppm h AOT40 (accumulated ozone over threshold 40). This is in the same order of magnitude as the response observed in [...] in 83 Swiss permanent forest observation plots and of Picea abies in 61 plots was evaluated for 11 and 8 consecutive years, respectively, using branches harvested every 4 years. The data were assessed as
Student Spotlight: Maryam Tavakkoli (Page)
https://www.swisstph.ch/de/impact-stories/student-spotlight-maryam-tavakkoli
information about deaths is essential to set priorities and develop effective policies. However, half of the countries around the world do not have a reliable source of information for road traffic injuries [...] internship at the World Health Organization? During last two years, I had the privilege to work with the World Health Organization (WHO) on two, multi-country workshops on improving data for road traffic [...] registration systems. One of the highlights of my internship was meeting...
Limited polymorphism in <em>Plasmodium falciparum</em> sexual-stage antigens (Publications)
Here we report the analysis of diversity in the three gametocyte-specific genes Pfs16, Pfs48/45, and Pfs230. In addition to the previously published data, limited polymorphism was found in the coding sequences [...] Larger polymorphism was identified in Pfs230, which might allow the development of a discriminating PCR-based genotyping scheme for transmission studies. However, the limited polymorphism in Pfs16 and Pfs48/45 [...] In areas highly endemic for malaria, individuals are frequently...
Limited polymorphism in <em>Plasmodium falciparum</em> sexual-stage antigens (Publications)
Here we report the analysis of diversity in the three gametocyte-specific genes Pfs16, Pfs48/45, and Pfs230. In addition to the previously published data, limited polymorphism was found in the coding sequences [...] Larger polymorphism was identified in Pfs230, which might allow the development of a discriminating PCR-based genotyping scheme for transmission studies. However, the limited polymorphism in Pfs16 and Pfs48/45 [...] In areas highly endemic for malaria, individuals are frequently...
Generation of aurachin derivatives by whole-cell biotransformation and evaluation of their antiprotozoal properties (Publications)
The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria, Plasmodium spp. In this study, we show that aurachin D inhibits [...] coli strain, which converted the substrates into the desired analogs. None of the generated derivatives exhibited improved antiprotozoal properties in comparison to aurachin D. Obviously, the naturally occurring [...] structural modifications on the bioactivity of this natural product....
Generation of aurachin derivatives by whole-cell biotransformation and evaluation of their antiprotozoal properties (Publications)
The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria, Plasmodium spp. In this study, we show that aurachin D inhibits [...] coli strain, which converted the substrates into the desired analogs. None of the generated derivatives exhibited improved antiprotozoal properties in comparison to aurachin D. Obviously, the naturally occurring [...] structural modifications on the bioactivity of this natural product....
Nanomimics of host cell membranes block invasion and expose invasive malaria parasites (Publications)
more than 2 orders of magnitude higher than the soluble form of the receptor, which can be explained by multivalent interactions of several receptors on one nanomimic with multiple ligands on the infective [...] nanotechnological strategy in which the nanostructure itself represents the active substance with no necessity to release compounds to attain therapeutic effect and which might act in a drug- and vaccine-like [...] model for the initial validation of this approach. Stable...
Nanomimics of host cell membranes block invasion and expose invasive malaria parasites (Publications)
more than 2 orders of magnitude higher than the soluble form of the receptor, which can be explained by multivalent interactions of several receptors on one nanomimic with multiple ligands on the infective [...] nanotechnological strategy in which the nanostructure itself represents the active substance with no necessity to release compounds to attain therapeutic effect and which might act in a drug- and vaccine-like [...] model for the initial validation of this approach. Stable...
Carotid intima-media thickness as a biomarker of subclinical atherosclerosis (Publications)
atherosclerosis. CIMT is measured in B-mode ultrasound images of the carotid tree as a typical double line of the arterial wall. CIMT is best visible in the measurement segment of the distal common carotid [...] e risk in order to readjust cardiovascular risk. Plaques in the carotid tree and thickening of the CIMT are different atherosclerotic processes. From childhood to early adulthood CIMT is the only athe [...] structured training of sonographer and reader is important for valid and...
