Parasite Chemotherapy (Page)
https://www.swisstph.ch/de/about/mpi/parasite-chemotherapy
Another element of the activities is to study the transmission of trypanosomes by the tsetse fly vector in order to gain more knowledge about the life cycle of the parasite and the function of certain [...] research and control. The Swiss Agency for Development and Cooperation (SDC) has awarded the network a second phase of support for 2004-2006. A key objective for this phase was to involve the network in international [...] Chemotherapy Unit The Parasite Chemotherapy Unit (PCU) is a drug...
Vector Research and Control (Page)
https://www.swisstph.ch/de/about/eph/vector-biology/vector-research-and-control
mosquito species of which the Asian tiger mosquito, Aedes albopictus is of particular concern because it is a vector competent for several viruses including Zika, chikungunya and dengue. The Vector Biology [...] evaluate new tools for the surveillance and control of mosquitoes and offer services to industry for testing public health pesticide products. The group is also actively contributing to research training [...] G roup of E ntomology in the Upper R hine valley) is an EU-funded INTERREG-V...
Genetic characterization of<em> Legionella pneumophila</em> isolated from a common watershed in Comunidad Valenciana, Spain (Publications)
locus present in the BV populations. This differentiation is still detectable when the 10 loci considered are analyzed independently, despite the relatively high incidence of the most common genetic variant [...] environmental sources. In order to establish control measures and study the sources of outbreaks it is essential to know extent and distribution of strain variants of this bacterium in the environment. Sporadic [...] differentiation at shorter geographic distances, which in this case...
Genetic characterization of<em> Legionella pneumophila</em> isolated from a common watershed in Comunidad Valenciana, Spain (Publications)
locus present in the BV populations. This differentiation is still detectable when the 10 loci considered are analyzed independently, despite the relatively high incidence of the most common genetic variant [...] environmental sources. In order to establish control measures and study the sources of outbreaks it is essential to know extent and distribution of strain variants of this bacterium in the environment. Sporadic [...] differentiation at shorter geographic distances, which in this case...
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities (Publications)
purines tested for their effects on purine transport in T. b. brucei displayed at best a moderate affinity for the transporters. It is highly probable that the large hydrophobic substitutions, which bestow high [...] coefficient values on the analogs, allow them to diffuse across the membrane. Consistent with this view, the analogs were as effective against a T. b. brucei strain lacking the P2 nucleoside transporter [...] forms in vitro. The most active were...
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities (Publications)
purines tested for their effects on purine transport in T. b. brucei displayed at best a moderate affinity for the transporters. It is highly probable that the large hydrophobic substitutions, which bestow high [...] coefficient values on the analogs, allow them to diffuse across the membrane. Consistent with this view, the analogs were as effective against a T. b. brucei strain lacking the P2 nucleoside transporter [...] forms in vitro. The most active were...
SOPHYA - Swiss children's Objectively measured PHYsical Activity (Projects)
https://www.swisstph.ch/de/projects/project-detail/project/sophya-swiss-childrens-objectively-measured-physical-activity
” survey, which is the basis for the recruitment. The aim of the SOPHYA study is to provide adequate information about children’s physical activity in order to compare it internationally and to identify [...] allocated individually using the coordinates of the children’s addresses. Some sociodemographic data and information about sport activities can be taken from the interview performed for the “Sportobservatorium” [...] their neighbourhood the simultaneous objective measurement of the physical...
A novel multiple-instance learning-based approach to computer-aided detection of tuberculosis on chest x-rays (Publications)
drawbacks of the former related to underestimation of the positive instances and costly iteration. The key of the proposed method is to use probability estimates instead of decision values to guide the MIL procedure [...] conducted. The area under the receiver operating characteristic curve was utilized as a performance measure. With the first database, for which training lesion annotations were available, the supervised [...] difference with respect to the previous image set, the most appealing...
A novel multiple-instance learning-based approach to computer-aided detection of tuberculosis on chest x-rays (Publications)
drawbacks of the former related to underestimation of the positive instances and costly iteration. The key of the proposed method is to use probability estimates instead of decision values to guide the MIL procedure [...] conducted. The area under the receiver operating characteristic curve was utilized as a performance measure. With the first database, for which training lesion annotations were available, the supervised [...] difference with respect to the previous image set, the most appealing...
Do holes in long-lasting insecticidal nets compromise their efficacy against pyrethroid resistant <em>Anopheles gambiae</em> and <em>Culex... (Publications)
become torn. The World Health Organization has proposed a threshold for when nets are "too torn" at 1,000 cm2 for rectangular holes and 790 cm2 for round holes. This study examines whether there is a threshold [...] though personal protection by LLINs against feeding mosquitoes is strongly reduced by holes, the insecticidal effect of LLINs is independent of the holed surface area, but strongly dependent on insecticide [...] threatens the effectiveness of long-lasting insecticidal nets (LLINs) as...
