Identifying individual, household and environmental risk factors for malaria infection on Bioko Island to inform interventions (Publications)
result of the scaling-up of control interventions. The aim of eliminating malaria from the Island remains elusive, however, underscoring the need to adapt control to the local context. Understanding the factors [...] according to need. The single most important risk factor identified was travel to mEG, in line with previous investigations, and represents a great challenge for the success of malaria control on the Island. [...] factors driving the risk of malaria infection is critical to inform...
Consultations in primary care for symptoms attributed to electromagnetic fields--a survey among general practitioners (Publications)
of mobile phones as the main EMF sources suspected to be associated to symptoms. GPs judged the association between EMF and the symptoms to be plausible in 54% of the cases. There was no combination of [...] consistently judged to be a plausible cause of the symptoms. CONCLUSION: In our survey, GPs often judged the association between the health problems and the suspected exposure to be plausible. This plausibility [...] up persons who attribute symptoms to EMF. It is unclear to what extent EMFs...
Consultations in primary care for symptoms attributed to electromagnetic fields--a survey among general practitioners (Publications)
of mobile phones as the main EMF sources suspected to be associated to symptoms. GPs judged the association between EMF and the symptoms to be plausible in 54% of the cases. There was no combination of [...] consistently judged to be a plausible cause of the symptoms. CONCLUSION: In our survey, GPs often judged the association between the health problems and the suspected exposure to be plausible. This plausibility [...] up persons who attribute symptoms to EMF. It is unclear to what extent EMFs...
Structure-activity relationships for ferriprotoporphyrin IX association and beta-hematin inhibition by 4-aminoquinolines using experimental and <em>ab... (Publications)
compared with the findings of this study. Experimentally, logK values for the simple 4-aminoquinoline series (R=H) were found to correlate with the hydrophobicity constant (?) of the group X. The logK values [...] values for the series with R=Me and EtNH2 were found to correlate with those of the series with R=H. The log of the 50% ?-hematin inhibitory activity (logBHIA50) was found to correlate with logK and either [...] charges were investigated. The best correlations were found with CHelpG...
Structure-activity relationships for ferriprotoporphyrin IX association and beta-hematin inhibition by 4-aminoquinolines using experimental and <em>ab... (Publications)
compared with the findings of this study. Experimentally, logK values for the simple 4-aminoquinoline series (R=H) were found to correlate with the hydrophobicity constant (?) of the group X. The logK values [...] values for the series with R=Me and EtNH2 were found to correlate with those of the series with R=H. The log of the 50% ?-hematin inhibitory activity (logBHIA50) was found to correlate with logK and either [...] charges were investigated. The best correlations were found with CHelpG...
Role of immune cells in animal models for inherited neuropathies: facts and visions (Publications)
investigate the pathogenetic role of lymphocytes, the myelin mutants were cross-bred with recombination activating gene 1 (RAG-1)-deficient mice, which lack mature T- and B-lymphocytes. The immunodeficient myelin [...] ng double mutants the numbers of macrophages were not elevated in the peripheral nerves, and the demyelinating phenotype was less severe than in the genuine P0+/- mice, demonstrating that macrophages are [...] involved in the pathogenesis of genetically mediated demyelination. We...
Role of immune cells in animal models for inherited neuropathies: facts and visions (Publications)
investigate the pathogenetic role of lymphocytes, the myelin mutants were cross-bred with recombination activating gene 1 (RAG-1)-deficient mice, which lack mature T- and B-lymphocytes. The immunodeficient myelin [...] ng double mutants the numbers of macrophages were not elevated in the peripheral nerves, and the demyelinating phenotype was less severe than in the genuine P0+/- mice, demonstrating that macrophages are [...] involved in the pathogenesis of genetically mediated demyelination. We...
Priority setting in early childhood development: an analytical framework for economic evaluation of interventions (Publications)
there is currently no standardised framework that allows a comparison of the relative cost-effectiveness of these interventions. METHODS: We first reviewed the existing literature to document the main [...] on the immediate impact of interventions on motor, cognitive, language and socioemotional skills. Last, we apply our framework to compute the relative cost-effectiveness of interventions for which recent [...] BACKGROUND: Early childhood development (ECD) sets the foundation for healthy and...
Priority setting in early childhood development: an analytical framework for economic evaluation of interventions (Publications)
there is currently no standardised framework that allows a comparison of the relative cost-effectiveness of these interventions. METHODS: We first reviewed the existing literature to document the main [...] on the immediate impact of interventions on motor, cognitive, language and socioemotional skills. Last, we apply our framework to compute the relative cost-effectiveness of interventions for which recent [...] BACKGROUND: Early childhood development (ECD) sets the foundation for healthy and...
Social accountability for reproductive, maternal, newborn, child and adolescent health: a review of reviews (Publications)
clear. We addressed this gap by conducting a review of reviews in order to summarise the current evidence on social accountability for RMNCAH, identify factors contributing to intermediary outcomes and [...] perinatal mortality audits, from which we extracted information relating to community involvement in audits. Our findings confirmed that there is extensive and growing evidence for social accountability approaches [...] have been made to hold duty-bearers to account for their commitments to...
