Group | Helminths and Health

Helminth infections are a group of neglected tropical diseases that have a significant impact on human health. Our research group aims to understand the diversity of parasitic helminths, their epidemiology, and their impact on health at the individual and population levels, as well as to design and evaluate adequate control strategies. The group has developed a particular interest in and expertise of helminthiases in Southeast Asia, East Africa and Siberia (Russian Federation).

Helminth Infections in Southeast Asia

Southeast Asia, particularly Laos and Cambodia, is especially interesting due to its unique socio-cultural and eco-epidemiological environment within the Mekong sub-region. Mekong schistosomiasis (Schistosoma mekongi), liver fluke (Opisthorchis viverrini), threadworm (Strongyloides stercoralis) and co-infections with soil-transmitted helminths are highly prevalent, frequently leading to polyparasitism, as well as liver and intestinal morbidity. Through collaborative research, we assess the contribution of helminth infections to the overall infection and morbidity burden.

Schistosomiasis on Zanzibar

On the islands of Unguja and Pemba, which belong to the United Republic of Tanzania, our research focuses on transdisciplinary intervention approaches that can contribute to interrupting the transmission of urogenital schistosomiasis on Zanzibar. In addition to preventive chemotherapy, we explore the impact of snail control and novel behaviour change approaches. We also collaborate with other international institutions on developing and evaluating new diagnostic tests for urogenital schistosomiasis.

Liver Fluke in Siberia

In rural Siberia in the Russian Federation, the liver fluke (Opisthorchis felineus) has been neglected for several decades. Our work contributes to  clarifying the epidemiology, infection and morbidity burden in this region.