Hiza H, Hella J, Arbués A, Sasamalo M, Misana V, Fellay J, Gagneux S, Reither K, Portevin D. CD38 expression by antigen-specific CD4 t cells is significantly restored 5 months after treatment initiation independently of sputum bacterial load at the time of tuberculosis diagnosis. Front Med. 2022;9:821776. DOI: 10.3389/fmed.2022.821776

2022
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Vaezipour N, Fritschi N, Brasier N, Bélard S, Domínguez J, Tebruegge M, Portevin D, Ritz N. Towards accurate point-of-care tests for tuberculosis in children. Pathogens. 2022;11(3):327. DOI: 10.3390/pathogens11030327

2022
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Xu Z.M, Rüeger S, Zwyer M, Brites D, Hiza H, Reinhard M, Rutaihwa L, Borrell S, Isihaka F, Temba H, Maroa T, Naftari R, Hella J, Sasamalo M, Reither K, Portevin D, Gagneux S, Fellay J. Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations. PLoS Comput Biol. 2022;18(1):e1009628. DOI: 10.1371/journal.pcbi.1009628

2022
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Arbués A, Schmidiger S, Kammüller M, Portevin D. Extracellular matrix-induced GM-CSF and hypoxia promote immune control of Mycobacterium tuberculosis in human in vitro granulomas. Front Immunol. 2021;12:727508. DOI: 10.3389/fimmu.2021.727508

2021
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Hiza H, Hella J, Arbués A, Magani B, Sasamalo M, Gagneux S, Reither K, Portevin D. Case-control diagnostic accuracy study of a non-sputum CD38-based TAM-TB test from a single milliliter of blood. Sci Rep. 2021;11(1):13190. DOI: 10.1101/2021.03.10.21253246

2021
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Arbués A, Brees D, Chibout S.D, Fox T, Kammüller M, Portevin D. TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis. PLoS Pathog. 2020;16(2):e1008312. DOI: 10.1371/journal.ppat.1008312

2020
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Arbués A, Kammüller M, Portevin D. Generating three-dimensional human granulomas in vitro to study Mycobacterium tuberculosis-host interaction. Bio Protoc. 2020;10(22):e3820. DOI: 10.21769/BioProtoc.3820

2020
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Amelio P, Portevin D, Hella J, Reither K, Kamwela L, Lweno O, Tumbo A, Geoffrey L, Ohmiti K, Ding S, Pantaleo G, Daubenberger C, Perreau M. HIV infection functionally impairs Mycobacterium tuberculosis-specific CD4 and CD8 T-cell responses. J Virol. 2019;93(5):e01728-18. DOI: 10.1128/JVI.01728-18

2019
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Steiner-Monard V, Kamaka K, Karoui O, Roethlisberger S, Audran R, Daubenberger C, Fayet-Mello A, Erdmann-Voisin A, Felger I, Geiger K, Govender L, Houard S, Huber E, Mayor C, Mkindi C, Portevin D, Rusch S, Schmidlin S, Tiendrebeogo R.W, Theisen M, Thierry A.C, Vallotton L, Corradin G, Leroy O, Abdulla S, Shekalaghe S, Genton B, Spertini F, Jongo S.A. The candidate blood-stage malaria vaccine P27A induces a robust humoral response in a fast track to the field phase I trial in exposed and non exposed volunteers. Clin Infect Dis. 2019;68(3):466-474. DOI: 10.1093/cid/ciy514

2019
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Boillat-Blanco N, Tumbo A.N, Perreau M, Amelio P, Ramaiya K.L, Mganga M, Schindler C, Gagneux S, Reither K, Probst-Hensch N, Pantaleo G, Daubenberger C, Portevin D. Hyperglycaemia is inversely correlated with live M. bovis BCG-specific CD4+ T cell responses in Tanzanian adults with latent or active tuberculosis. Immun Inflamm Dis. 2018;6(2):345-353. DOI: 10.1002/iid3.222

2018
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Vogel G, Cuénod A, Mouchet R, Strauss A, Daubenberger C, Pflueger V, Portevin D. Functional characterization and phenotypic monitoring of human hematopoietic stem cell expansion and differentiation of monocytes and macrophages by whole-cell mass spectrometry. Stem Cell Res. 2018;26:47-54. DOI: 10.1016/j.scr.2017.11.013

2018
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Amelio P, Portevin D, Reither K, Mhimbira F, Mpina M, Tumbo A, Nickel B, Marti H, Knopp S, Ding S, Penn-Nicholson A, Darboe F, Ohmiti K, Scriba T.J, Pantaleo G, Daubenberger C, Perreau M. Mixed Th1 and Th2 Mycobacterium tuberculosis-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania. PLoS Negl Trop Dis. 2017;11(7):e0005817. DOI: 10.1371/journal.pntd.0005817

2017
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Portevin D, Moukambi F, Mpina M, Bauer A, Haraka F, Chachage M, Metzger P, Saathoff E, Clowes P, Ntinginya N.E, Rachow A, Hoelscher M, Reither K, Daubenberger C.A, Geldmacher C. Maturation and mip-1beta production of cytomegalovirus-specific T cell responses in Tanzanian children, adolescents and adults: impact by HIV and Mycobacterium tuberculosis co-infections. PLoS One. 2015;10(5):e0126716. DOI: 10.1371/journal.pone.0126716

2015
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Portevin D, Pflüger V, Otieno P, Brunisholz R, Vogel G, Daubenberger C. Quantitative whole-cell MALDI-TOF MS fingerprints distinguishes human monocyte sub-populations activated by distinct microbial ligands. BMC Biotechnol. 2015;15:24. DOI: 10.1186/s12896-015-0140-1

2015
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Portevin D, Moukambi F, Clowes P, Bauer A, Chachage M, Ntinginya E.N, Mfinanga E, Said K, Haraka F, Rachow A, Saathoff E, Mpina M, Jugheli L, Lwilla F, Marais B.J, Hoelscher M, Daubenberger C, Reither K, Geldmacher C. Assessment of the novel T-cell activation marker-tuberculosis assay for diagnosis of active tuberculosis in children: a prospective proof-of-concept study. Lancet Infect Dis. 2014;14(10):931-938. DOI: 10.1016/S1473-3099(14)70884-9

2014
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Portevin D, Sukumar S, Coscolla M, Shui G, Li B, Guan X.L, Bendt A.K, Young D, Gagneux S, Wenk M.R. Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesis. Microbiologyopen. 2014;3(6):823-835. DOI: 10.1002/mbo3.193

2014
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Portevin D, Young D. Natural killer cell cytokine response to M. bovis BCG is associated with inhibited proliferation, increased apoptosis and ultimate depletion of NKp44(+)CD56(bright) cells. PLoS One. 2013;8(7):e68864. DOI: 10.1371/journal.pone.0068864

2013
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Via L.E, Weiner D.M, Schimel D, Lin P.L, Dayao E, Tankersley S.L, Cai Y, Coleman M.T, Tomko J, Paripati P, Orandle M, Kastenmayer R.J, Tartakovsky M, Rosenthal A, Portevin D, Eum S.Y, Lahouar S, Gagneux S, Young D.B, Flynn J.L, Barry III C.E. Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus). Infect Immun. 2013;81(8):2909-2919. DOI: 10.1128/IAI.00632-13

2013
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Portevin D, Gagneux S, Comas I, Young D. Human macrophage responses to clinical isolates from the Mycobacterium tuberculosis complex discriminate between ancient and modern lineages. PLoS Pathog. 2011;7(3):e1001307. DOI: 10.1371/journal.ppat.1001307

2011
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PubMed