Publications

Beynon F, Mhalu G, Kumar D, Cicconi S, Langet H, Levine G.A, Agarwal G, Festo C, Glass T.R, Jacob A, Kumar G, Lwambura S, Matata L, Mkopi A, Moshiro R, Schaer F, Bandi V, Bohle L.F, Emmanuel-Fabula M, Horlacher M, Horton S, Maiba J, Makawia S, Masanja N, Mjungu D, Mtebene I.E, Odek O, Oliveira V, Pantjushenko E, Reus E, Ruffo M, Sharma K, Storey H, Tyagi M, D'Acremont V, Masanja H, Awasthi S, Wyss K, TIMCI Collaborator Group. Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in India and Tanzania on hospitalisation and mortality: the TIMCI pragmatic cluster randomised controlled trial. EClinicalMedicine. 2025;85:103306. DOI: 10.1016/j.eclinm.2025.103306

Cobuccio L.G, Faivre V, Tan R, Vonlanthen A, Beynon F, Barchichat E, Fresco A, Girard Q, Ucak S, Schaufelberger S, Mtebene I.E, Agrea P, Kalisa E, Levine G.A, Norris M, Renggli S, Miauton A, Cleveley L, Keitel K, Thabard J, D'Acremont V, Kulinkina A.V. medAL-suite: a software solution for creating and deploying complex clinical decision support algorithms. BMC Med Inform Decis Mak. 2025;25:249. DOI: 10.1186/s12911-025-03077-6

Langet H, Faye P.M, Njiri F, Cicconi S, Levine G.A, Glass T.R, Kosgei R.J, Ngari K, Schaer F, Thiongane A, Tine J.A.D, Ba M, Bohle L.F, Emmanuel-Fabula M, Faye M.M, Horton S, Miheso A, Mugo M, Ngutu M, Ruffo M, Shauri J, Sougou N.M, D’Acremont V, Wyss K, Ndiaye O, Beynon F, The TIMCI Collaborator Group. Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in Kenya and Senegal on referral and antibiotic prescription: the TIMCI quasi-experimental pre-post study. eClinicalMedicine. 2025;83:103196. DOI: 10.1016/j.eclinm.2025.103196

Tan R, Chandna A, Colbourn T, Hooli S, King C, Lufesi N, McCollum E.D, Mwansambo C, Mathew J.L, Cutland C.L, Madhi S.A, Nunes M, Basnet S, Strand T.A, O'Grady K.F, Gessner B, Addo-Yobo E, Chisaka N, Hibberd P, Jeena P.M, Lozano J.M, MaLeod W.B, Patel A, Thea D.M, Nguyen N.T.V, Lucero M, Akram Uz Zaman S.M, Bhatnagar S, Wadhwa N, Lodha R, Aneja S, Santosham M, Awasthi S, Bavdekar A, Chou M, Nymadawa P, Pape J.W, Paranhos-Baccala G, Picot V.S, Rakoto-Andrianarivelo M, Rouzier V, Russomando G, Sylla M, Vanhems P, Wang J, Libster R, Clara A.W, Beynon F, Levine G, Rees C.A, Neuman M.I, Qazi S, Nisar Y.B, World Health Organization PREPARE study group. Development and validation of a novel clinical risk score to predict hypoxaemia in children with pneumonia using the WHO PREPARE dataset. BMJ Glob Health. 2025;10(7):e017256. DOI: 10.1136/bmjgh-2024-017256

Tyagi M, Kumar D, Sharma K, Beynon F, Kumar G, Langet H, Levine G.A, Ruffo M.A, Fabula M.E, D'Acremont V, Wyss K, Bohle L.F, Awasthi S. Barriers and enablers of using a clinical decision support algorithm to consult sick children at primary health facilities: a qualitative study from Uttar Pradesh, India. Clin Epidemiol Glob Health. 2025;34:102038. DOI: doi.org/10.1016/j.cegh.2025.102038

von Kalckreuth V, Rwandarwacu V.P, Cobuccio L, Dusengumuremyi T, Levine G.A, Norris M, Miauton A, Tan R, Rusingiza E, Umuhoza C, Rutagarama F.H, Muhire H.B, Nkuranga J.B, Vaezipour N, Keitel K, Beynon F, Tuyisenge L, D'Acremont V, Kulinkina A.V. ePOCT+ Rwanda: a clinical decision support algorithm for managing sick children below 15 years of age in primary healthcare settings. Rwanda J Med Health Sci. 2025;8(1):148-162. DOI: 10.4314/rjmhs.v8i1.13

Beynon F, Langet H, Bohle L.F, Awasthi S, Ndiaye O, Machoki M'Imunya J, Masanja H, Horton S, Ba M, Cicconi S, Emmanuel-Fabula M, Faye P.M, Glass T.R, Keitel K, Kumar D, Kumar G, Levine G.A, Matata L, Mhalu G, Miheso A, Mjungu D, Njiri F, Reus E, Ruffo M, Schär F, Sharma K, Storey H.L, Masanja I, Wyss K, D'Acremont V, TIMCI Collaborator Group. The Tools for Integrated Management of Childhood Illness (TIMCI) study protocol: a multi-country mixed-method evaluation of pulse oximetry and clinical decision support algorithms. Glob Health Action. 2024;17:2326253. DOI: 10.1080/16549716.2024.2326253

Tan R, Kavishe G, Luwanda L.B, Kulinkina A.V, Renggli S, Mangu C, Ashery G, Jorram M, Mtebene I.E, Agrea P, Mhagama H, Vonlanthen A, Faivre V, Thabard J, Levine G, Le Pogam M.A, Keitel K, Taffé P, Ntinginya N, Masanja H, D'Acremont V. A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial. Nat Med. 2024;30:76-84. DOI: 10.1038/s41591-023-02633-9

Zay Ya K, Lambiris M.J, Levine G.A, Tediosi F, Fink G. Coverage of policies to improve antimicrobial stewardship in human medicine in low and middle income countries: results from the Global Survey of Experts on Antimicrobial Resistance. BMC Public Health. 2024;24:2297. DOI: 10.1186/s12889-024-19542-2

Tan R, Cobuccio L, Beynon F, Levine G.A, Vaezipour N, Luwanda L.B, Mangu C, Vonlanthen A, De Santis O, Salim N, Manji K, Naburi H, Chirande L, Matata L, Bulongeleje M, Moshiro R, Miheso A, Arimi P, Ndiaye O, Faye M, Thiongane A, Awasthi S, Sharma K, Kumar G, Van De Maat J, Kulinkina A, Rwandarwacu V, Dusengumuremyi T, Nkuranga J.B, Rusingiza E, Tuyisenge L, Hartley M.A, Faivre V, Thabard J, Keitel K, D'Acremont V. ePOCT+ and the medAL-suite: development of an electronic clinical decision support algorithm and digital platform for pediatric outpatients in low- and middle-income countries. PLOS Digit Health. 2023;2:e0000170. DOI: 10.1371/journal.pdig.0000170

Levine G, Bielicki J, Fink G. Cumulative antibiotic exposure in the first five years of life: estimates for 45 low- and middle-income countries from demographic and health survey data. Clin Infect Dis. 2022;75(9):1537-1547. DOI: 10.1093/cid/ciac225

Levine G, Salifu A, Mohammed I, Fink G. Mobile nudges and financial incentives to improve coverage of timely neonatal vaccination in rural areas (GEVaP trial): a 3-armed cluster randomized controlled trial in Northern Ghana. PLoS One. 2021;16(5):e0247485. DOI: 10.1371/journal.pone.0247485

Wallenborn J.T, Levine G.A, Carreira Dos Santos A, Grisi S, Brentani A, Fink G. Breastfeeding, physical growth, and cognitive development. Pediatrics. 2021;147(5):e2020008029. DOI: 10.1542/peds.2020-008029

Tan R, Kagoro F, Levine G.A, Masimba J, Samaka J, Sangu W, Genton B, D'Acremont V, Keitel K. Clinical outcome of febrile Tanzanian children with severe malnutrition using anthropometry in comparison to clinical signs. Am J Trop Med Hyg. 2020;102(2):427-435. DOI: 10.4269/ajtmh.19-0553

Lavoie P.M, Popescu C.R, Molyneux E.M, Wynn J.L, Chiume M, Keitel K, Lufesi N, Levine G.A, Ansermino J.M, Kissoon N. Rethinking management of neonates at risk of sepsis. Lancet. 2019;394(10195):279-281. DOI: 10.1016/S0140-6736(19)31627-7