Publications

Röltgen K, Boyd S.D. Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning. Annu Rev Pathol. 2024;19:69-97. DOI: 10.1146/annurev-pathmechdis-031521-042754

Gao F, Mallajoysula V, Arunachalam P.S, van der Ploeg K, Manohar M, Röltgen K, Yang F, Wirz O, Hoh R, Haraguchi E, Lee J.Y, Willis R, Ramachandiran V, Li J, Kathuria K.R, Li C, Lee A.S, Shah M.M, Sindher S.B, Gonzalez J, Altman J.D, Wang T.T, Boyd S.D, Pulendran B, Jagannathan P, Nadeau K.C, Davis M.M. Spheromers reveal robust T cell responses to the Pfizer/BioNTech vaccine and attenuated peripheral CD8(+) T cell responses post SARS-CoV-2 infection. Immunity. 2023;56(4):864-878 e4. DOI: 10.1016/j.immuni.2023.03.005

Goldman J.D, Wang K, Röltgen K, Nielsen S.C.A, Roach J.C, Naccache S.N, Yang F, Wirz O.F, Yost K.E, Lee J.Y, Chun K, Wrin T, Petropoulos C.J, Lee I, Fallen S, Manner P.M, Wallick J.A, Algren H.A, Murray K.M, Hadlock J, Chen D, Dai C.L, Yuan D, Su Y, Jeharajah J, Berrington W.R, Pappas G.P, Nyatsatsang S.T, Greninger A.L, Satpathy A.T, Pauk J.S, Boyd S.D, Heath J.R. Reinfection with SARS-CoV-2 and waning humoral immunity: a case report. Vaccines (Basel). 2022;11(1):5. DOI: 10.3390/vaccines11010005

Jia X, Cao S, Lee A.S, Manohar M, Sindher S.B, Ahuja N, Artandi M, Blish C.A, Blomkalns A.L, Chang I, Collins W.J, Desai M, Din H.N, Do E, Fernandes A, Geng L.N, Rosenberg-Hasson Y, Mahoney M.R, Glascock A.L, Chan L.Y, Fong S.Y, CLIAHUB Consortium, Chan Zuckerberg Biohub, Phelps M, Raeber O, Stanford COVID-19 Biobank Study Group, Purington N, Röltgen K, Rogers A.J, Snow T, Wang T.T, Solis D, Vaughan L, Verghese M, Maecker H, Wittman R, Puri R, Kistler A, Yang S, Boyd S.D, Pinsky B.A, Chinthrajah S, Nadeau K.C. Anti-nucleocapsid antibody levels and pulmonary comorbid conditions are linked to post-COVID-19 syndrome. JCI Insight. 2022;7(13):e156713. DOI: 10.1172/jci.insight.156713

Pillet S, Arunachalam P.S, Andreani G, Golden N, Fontenot J, Aye P.P, Röltgen K, Lehmicke G, Gobeil P, Dubé C, Trépanier S, Charland N, D'Aoust M.A, Russell-Lodrigue K, Monjure C, Blair R.V, Boyd S.D, Bohm R.P, Rappaport J, Villinger F, Landry N, Pulendran B, Ward B.J. Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates. Cell Mol Immunol. 2022;19(2):222-233. DOI: 10.1038/s41423-021-00809-2

Pluschke G,Röltgen K, eds. Mycobacterium ulcerans: methods and protocols. New York, NY: Humana Press, 2022. DOI: 10.1007/978-1-0716-1779-3

Pluschke G, Röltgen K. Overview: development of drugs against Mycobacterium ulcerans. In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, 185-187. New York, NY: Humana, 2022. (Methods in molecular biology: 2387). DOI: 10.1007/978-1-0716-1779-3_17

Pluschke G, Röltgen K. Preface. In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, V-VI. New York, NY: Humana, 2022. DOI: 10.1007/978-1-0716-1779-3_1

Röltgen K, Johnson P.D.R, Pluschke G. Epidemiology of Buruli ulcer. In: Nunzi E,Massone C,Portaels F, eds. Leprosy and Buruli ulcer. A practical guide, 541-550. Cham: Springer Nature, 2022. DOI: 10.1007/978-3-030-89704-8_47

Röltgen K, Nielsen S.C.A, Silva O, Younes S.F, Zaslavsky M, Costales C, Yang F, Wirz O.F, Solis D, Hoh R.A, Wang A, Arunachalam P.S, Colburg D, Zhao S, Haraguchi E, Lee A.S, Shah M.M, Manohar M, Chang I, Gao F, Mallajosyula V, Li C, Liu J, Shoura M.J, Sindher S.B, Parsons E, Dashdorj N.J, Dashdorj N.D, Monroe R, Serrano G.E, Beach T.G, Chinthrajah R.S, Charville G.W, Wilbur J.L, Wohlstadter J.N, Davis M.M, Pulendran B, Troxell M.L, Sigal G.B, Natkunam Y, Pinsky B.A, Nadeau K.C, Boyd S.D. Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination. Cell. 2022;185(6):1025-1040 e14. DOI: 10.1016/j.cell.2022.01.018

Röltgen K, Pluschke G. Overview: Mycobacterium ulcerans disease (Buruli ulcer). In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, 3-6. New York, NY: Humana, 2022. (Methods in molecular biology: 2387). DOI: 10.1007/978-1-0716-1779-3_1

Röltgen K, Pluschke G. Overview: mycolactone, the macrolide toxin of Mycobacterium ulcerans. In: Pluschke G,Röltgen K, eds. Mycobacterium ulcerans:, 105-108. New York, NY: Humana, 2022. (Methods in molecular biology: 2387). DOI: 10.1007/978-1-0716-1779-3_11

Serrano G.E, Walker J.E, Tremblay C, Piras I.S, Huentelman M.J, Belden C.M, Goldfarb D, Shprecher D, Atri A, Adler C.H, Shill H.A, Driver-Dunckley E, Mehta S.H, Caselli R, Woodruff B.K, Haarer C.F, Ruhlen T, Torres M, Nguyen S, Schmitt D, Rapscak S.Z, Bime C, Peters J.L, Alevritis E, Arce R.A, Glass M.J, Vargas D, Sue L.I, Intorcia A.J, Nelson C.M, Oliver J, Russell A, Suszczewicz K.E, Borja C.I, Cline M.P, Hemmingsen S.J, Qiji S, Hobgood H.M, Mizgerd J.P, Sahoo M.K, Zhang H, Solis D, Montine T.J, Berry G.J, Reiman E.M, Röltgen K, Boyd S.D, Pinsky B.A, Zehnder J.L, Talbot P, Desforges M, DeTure M, Dickson D.W, Beach T.G. SARS-CoV-2 brain regional detection, histopathology, gene expression, and immunomodulatory changes in decedents with COVID-19. J Neuropathol Exp Neurol. 2022;81(9):666-695. DOI: 10.1093/jnen/nlac056

Arunachalam P.S, Walls A.C, Golden N, Atyeo C, Fischinger S, Li C, Aye P, Navarro M.J, Lai L, Edara V.V, Röltgen K, Rogers K, Shirreff L, Ferrell D.E, Wrenn S, Pettie D, Kraft J.C, Miranda M.C, Kepl E, Sydeman C, Brunette N, Murphy M, Fiala B, Carter L, White A.G, Trisal M, Hsieh C.L, Russell-Lodrigue K, Monjure C, Dufour J, Spencer S, Doyle-Meyers L, Bohm R.P, Maness N.J, Roy C, Plante J.A, Plante K.S, Zhu A, Gorman M.J, Shin S, Shen X, Fontenot J, Gupta S, O'Hagan D.T, Van Der Most R, Rappuoli R, Coffman R.L, Novack D, McLellan J.S, Subramaniam S, Montefiori D, Boyd S.D, Flynn J.L, Alter G, Villinger F, Kleanthous H, Rappaport J, Suthar M.S, King N.P, Veesler D, Pulendran B. Adjuvanting a subunit COVID-19 vaccine to induce protective immunity. Nature. 2021;594(7862):253-258. DOI: 10.1038/s41586-021-03530-2

Dashdorj N.J, Wirz O.F, Röltgen K, Haraguchi E, Buzzanco A.S, Sibai M, Wang H, Miller J.A, Solis D, Sahoo M.K, Arunachalam P.S, Lee A.S, Shah M.M, Liu J, Byambabaatar S, Bat-Ulzii P, Enkhbat A, Batbold E, Zulkhuu D, Ochirsum B, Khurelsukh T, Dalantai G, Burged N, Baatarsuren U, Ariungerel N, Oidovsambuu O, Bungert A.S, Genden Z, Yagaanbuyant D, Mordorj A, Pulendran B, Chinthrajah S, Nadeau K.C, Jardetzky T, Wilbur J.L, Wohlstadter J.N, Sigal G.B, Pinsky B.A, Boyd S.D, Dashdorj N.D. Direct comparison of antibody responses to four SARS-CoV-2 vaccines in Mongolia. Cell Host Microbe. 2021;29(12):1738-1743 e4. DOI: 10.1016/j.chom.2021.11.004

Day C.J, Röltgen K, Pluschke G, Jennings M.P. The cell surface protein MUL_3720 confers binding of the skin pathogen Mycobacterium ulcerans to sulfated glycans and keratin. PLoS Negl Trop Dis. 2021;15(2):e0009136. DOI: 10.1371/journal.pntd.0009136

Hogan C.A, Gombar S, Wang H, Röltgen K, Shi R.Z, Holubar M, Chang S.I, Lee G.M, Boyd S.D, Zehnder J, Pinsky B.A. Large-scale testing of asymptomatic healthcare personnel for severe acute respiratory syndrome coronavirus 2. Emerg Infect Dis. 2021;27(1):250-4. DOI: 10.3201/eid2701.203892

Lawrence L, Stevens B.A, Sahoo M.K, Huang C, Yamamoto F, Röltgen K, Wirz O, Zehnder J, Shi R.Z, Boyd S.D, Schoolnik G, Pinsky B.A, Hogan C.A. Plasma as an alternative COVID-19 diagnostic specimen in a hospitalized patient negative for SARS-CoV-2 by nasopharyngeal swab. Diagn Microbiol Infect Dis. 2021;100(3):115365. DOI: 10.1016/j.diagmicrobio.2021.115365

Nguyen K.D, Wirz O.F, Röltgen K, Pandey S, Tolentino L, Boyd S.D, Pham T.D. Efficient identification of high-titer anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody plasma samples by pooling method. Arch Pathol Lab Med. 2021;145(10):1221-1227. DOI: 10.5858/arpa.2021-0215-SA

Röltgen K, Boyd S.D. Antibody and B cell responses to SARS-CoV-2 infection and vaccination. Cell Host Microbe. 2021;29(7):1063-1075. DOI: 10.1016/j.chom.2021.06.009

Rosser J.I, Röltgen K, Dymock M, Shepard J, Martin A, Hogan C.A, Blomkalns A, Mathew R, Parsonnet J, Pinsky B.A, Maldonado Y.A, Boyd S.D, Chang S.I, Holubar M, Stanford Healthcare COVID-19 Workforce Response Group. Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) seroprevalence in healthcare personnel in northern California early in the coronavirus disease 2019 (COVID-19) pandemic. Infect Control Hosp Epidemiol. 2021;42(9):1053-1059. DOI: 10.1017/ice.2020.1358

Sibai M, Solis D, Röltgen K, Stevens B.A, Mfuh K.O, Sahoo M.K, Shi R.Z, Zehnder J, Boyd S.D, Pinsky B.A. Evaluation of SARS-CoV-2 total antibody detection via a lateral flow nanoparticle fluorescence immunoassay. J Clin Virol. 2021;139:104818. DOI: 10.1016/j.jcv.2021.104818

Truong T.T, Ryutov A, Pandey U, Yee R, Goldberg L, Bhojwani D, Aguayo-Hiraldo P, Pinsky B.A, Pekosz A, Shen L, Boyd S.D, Wirz O.F, Röltgen K, Bootwalla M, Maglinte D.T, Ostrow D, Ruble D, Han J.H, Biegel J.A, Li M, Huang C, Sahoo M.K, Pannaraj P.S, O'Gorman M, Judkins A.R, Gai X, Dien Bard J. Increased viral variants in children and young adults with impaired humoral immunity and persistent SARS-CoV-2 infection: a consecutive case series. EBioMedicine. 2021;67:103355. DOI: 10.1016/j.ebiom.2021.103355

Wagar L.E, Salahudeen A, Constantz C.M, Wendel B.S, Lyons M.M, Mallajosyula V, Jatt L.P, Adamska J.Z, Blum L.K, Gupta N, Jackson K.J.L, Yang F, Röltgen K, Roskin K.M, Blaine K.M, Meister K.D, Ahmad I.N, Cortese M, Dora E.G, Tucker S.N, Sperling A.I, Jain A, Davies D.H, Felgner P.L, Hammer G.B, Kim P.S, Robinson W.H, Boyd S.D, Kuo C.J, Davis M.M. Modeling human adaptive immune responses with tonsil organoids. Nat Med. 2021;27:125-135. DOI: 10.1038/s41591-020-01145-0

Wang H, Hogan C.A, Verghese M, Solis D, Sibai M, Huang C, Röltgen K, Stevens B.A, Yamamoto F, Sahoo M.K, Zehnder J, Boyd S.D, Pinsky B.A. SARS-CoV-2 nucleocapsid plasma antigen for diagnosis and monitoring of COVID-19. Clin Chem. 2021;68(1):204-213. DOI: 10.1093/clinchem/hvab216

Wang H, Wiredja D, Yang L, Bulterys P.L, Costales C, Röltgen K, Manalac J, Yee J, Zehnder J, Shi R.Z, Boyd S.D, Pinsky B.A. Case-control study of individuals with discrepant nucleocapsid and spike protein SARS-CoV-2 IgG results. Clin Chem. 2021;67(7):977-986. DOI: 10.1093/clinchem/hvab045

Wirz O.F, Röltgen K, Stevens B.A, Pandey S, Sahoo M.K, Tolentino L, Verghese M, Nguyen K, Hunter M, Snow T.T, Singh A.R, Blish C.A, Cochran J.R, Zehnder J.L, Nadeau K.C, Pinsky B.A, Pham T.D, Boyd S.D. Use of outpatient-derived COVID-19 convalescent plasma in COVID-19 patients before seroconversion. Front Immunol. 2021;12:739037. DOI: 10.3389/fimmu.2021.739037

Yang F, Nielsen S.C.A, Hoh R.A, Röltgen K, Wirz O.F, Haraguchi E, Jean G.H, Lee J.Y, Pham T.D, Jackson K.J.L, Roskin K.M, Liu Y, Nguyen K, Ohgami R.S, Osborne E.M, Nadeau K.C, Niemann C.U, Parsonnet J, Boyd S.D. Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues. Science. 2021;372(6543):738-741. DOI: 10.1126/science.abf6648

Nielsen S.C.A, Yang F, Jackson K.J.L, Hoh R.A, Röltgen K, Jean G.H, Stevens B.A, Lee J.Y, Rustagi A, Rogers A.J, Powell A.E, Hunter M, Najeeb J, Otrelo-Cardoso A.R, Yost K.E, Daniel B, Nadeau K.C, Chang H.Y, Satpathy A.T, Jardetzky T.S, Kim P.S, Wang T.T, Pinsky B.A, Blish C.A, Boyd S.D. Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2. Cell Host Microbe. 2020;28(4):516-525 e5. DOI: 10.1016/j.chom.2020.09.002

Pham T.D, Huang C, Wirz O.F, Röltgen K, Sahoo M.K, Layon A, Pandey S, Foung S.K, Boyd S.D, Pinsky B.A. SARS-CoV-2 RNAemia in a healthy blood donor 40 days after respiratory illness resolution. Ann Intern Med. 2020;173(10):853-854. DOI: 10.7326/L20-0725

Röltgen K, Pluschke G, Spencer J.S, Brennan P.J, Avanzi C. The immunology of other mycobacteria: M. ulcerans, M. leprae. Semin Immunopathol. 2020;42(3):333-353. DOI: 10.1007/s00281-020-00790-4

Röltgen K, Pluschke G. Buruli ulcer: the efficacy of innate immune defense may be a key determinant for the outcome of infection with Mycobacterium ulcerans. Front Microbiol. 2020;11:1018. DOI: 10.3389/fmicb.2020.01018

Röltgen K, Powell A.E, Wirz O.F, Stevens B.A, Hogan C.A, Najeeb J, Hunter M, Wang H, Sahoo M.K, Huang C, Yamamoto F, Manohar M, Manalac J, Otrelo-Cardoso A.R, Pham T.D, Rustagi A, Rogers A.J, Shah N.H, Blish C.A, Cochran J.R, Jardetzky T.S, Zehnder J.L, Wang T.T, Narasimhan B, Gombar S, Tibshirani R, Nadeau K.C, Kim P.S, Pinsky B.A, Boyd S.D. Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome. Sci Immunol. 2020;5(54):eabe0240. DOI: 10.1126/sciimmunol.abe0240

Pluschke G,Röltgen K, eds. Buruli ulcer: Mycobacterium ulcerans disease. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4

Röltgen K, Cruz I, Ndung'u J.M, Pluschke G. Laboratory diagnosis of Buruli ulcer: challenges and future perspectives. In: Pluschke G,Röltgen K, eds. Buruli ulcer: , 183-202. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4_10

Röltgen K, Pluschke G. Buruli ulcer: history and disease burden. In: Pluschke G,Röltgen K, eds. Buruli ulcer: , 1-42. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4_1

Tabah E.N, Johnson C.R, Degnonvi H, Pluschke G, Röltgen K. Buruli ulcer in Africa. In: Pluschke G,Röltgen K, eds. Buruli ulcer: , 43-60. Cham: Springer, 2019. DOI: 10.1007/978-3-030-11114-4_2

Lamelas A, Hamid A.M, Dangy J.P, Hauser J, Jud M, Röltgen K, Hodgson A, Junghanss T, Harris S.R, Parkhill J, Bentley S.D, Pluschke G. Loss of genomic diversity in a Neisseria meningitidis clone through a colonization bottleneck. Genome Biol Evol. 2018;10(8):2102-2109. DOI: 10.1093/gbe/evy152

Pinho-Nascimento C.A, Bratschi M.W, Höfer R, Soares C.C, Warryn L, Pecerska J, Minyem J.C, Paixão I.C.N.P, Baroni de Moraes M.T, Um Boock A, Niel C, Pluschke G, Röltgen K. Transmission of hepatitis B and D viruses in an African rural community. mSystems. 2018;3(5):e00120-18. DOI: 10.1128/mSystems.00120-18

Röltgen K, Rose N, Ruggieri A, Warryn L, Scherr N, Pinho-Nascimento C.A, Tamborrini M, Jaenisch T, Pluschke G. Development of dengue virus serotype-specific NS1 capture assays for the rapid and highly sensitive identification of the infecting serotype in human sera. J Immunol. 2018;200(200):3857-3866. DOI: 10.4049/jimmunol.1701790