Novel high-throughput screening method using quantitative PCR to determine the antimicrobial susceptibility of <em>Orientia tsutsugamushi... (Publications)
which showed azithromycin MICs of 0.0156 and 0.0313 mg/L, compared with 0.0078 and 0.0156 mg/L, respectively, in previous reports. The MIC of doxycycline for AFC-3 was 0.125 mg/L compared with > 4 mg/L in [...] in earlier reports. The final single screening concentrations were identified as: azithromycin, 0.125 mg/L; chloramphenicol, 8 mg/L; and doxycycline, 1 mg/L. Conclusions: This simplified procedure facilitates
Breaking the threshold: developing multivariable models using computer-aided chest X-ray analysis for tuberculosis triage (Publications)
(areas under the receiver operating characteristic curve (95%CI): software A, 0.91 (0.90-0.93); software B, 0.92 (0.91-0.93)). Compared to threshold scores, multivariable models increased specificity
Prospective multicentre accuracy evaluation of the FUJIFILM SILVAMP TB LAM test for the diagnosis of tuberculosis in people living with HIV... (Publications)
48·7-60·0), overall specificity was 85·2% (83·2-87·0) against eMRS. Sensitivity and specificity estimates varied between sites, ranging from 26·5% (95% CI: 17·4%-38·0%) to 73·2% (60·4%-83·0%), and 75·0 (65 [...] (65·0%-82·9%) to 96·5 (92·1%-98·5%), respectively. Post-hoc exploratory analysis identified significant variability in the performance of the six FujiLAM lots used in this study. Lot variability limited
Breaking the threshold: developing multivariable models using computer-aided chest X-ray analysis for tuberculosis triage (Publications)
(areas under the receiver operating characteristic curve (95%CI): software A, 0.91 (0.90-0.93); software B, 0.92 (0.91-0.93)). Compared to threshold scores, multivariable models increased specificity
Prospective multicentre accuracy evaluation of the FUJIFILM SILVAMP TB LAM test for the diagnosis of tuberculosis in people living with HIV... (Publications)
48·7-60·0), overall specificity was 85·2% (83·2-87·0) against eMRS. Sensitivity and specificity estimates varied between sites, ranging from 26·5% (95% CI: 17·4%-38·0%) to 73·2% (60·4%-83·0%), and 75·0 (65 [...] (65·0%-82·9%) to 96·5 (92·1%-98·5%), respectively. Post-hoc exploratory analysis identified significant variability in the performance of the six FujiLAM lots used in this study. Lot variability limited
Adherence to the management of type i diabetes among Palestinian patients in Nablus city: a cross-sectional study (Publications)
non-adherence to administering insulin on time. Age (r = 0.29, P < 0.05), A1C (r = 0.21, P < 0.05), sex (P < 0.05), and patient educational level (P < 0.05) were significantly related to adherence score. Adherence
Assessing the association between air pollution and child development in São Paulo, Brazil (Publications)
association between NO2 and children's cognitive development (beta -0.05, 95% CI [-0.20; 0.10]) or behavioural problems (beta 0.02, 95% CI [-0.80; 0.12]). CONCLUSION: No association between child cognition or
Effectiveness of four different interventions against <em>Schistosoma haematobium</em> in a seasonal transmission setting of Côte d'Ivoire: a cluster... (Publications)
in the biannual MDA, compared to the standard treatment arm (0.6% vs. 7.5%; odds ratio [OR] = 0.07, 95% confidence interval [CI] = 0.02 to 0.24). The prevalence in arms 2 and 4 was about 3.5%, which was [...] was not statistically significantly different from the standard strategy (both ORs 0.4, 95% CI = 0.1 to ~1.8). New cases of infection were still observed in all arms at study end. CONCLUSIONS: Biannual MDA
Fluctuating temperature modifies heat-mortality association around the globe (Publications)
with increments in TV, accounting for 0.70% (95% confidence interval [CI]: -0.33 to 1.69), 1.34% (95% CI: -0.14 to 2.73), 1.99% (95% CI: 0.29-3.57), and 2.73% (95% CI: 0.76-4.50) of total deaths for Q1-Q4 [...] TV, while the lowest AFs were observed in North America, with the values for Q4 of 1.74% (95% CI: -0.09 to 3.39). TV had a significant modification effect on the heat-mortality association, causing a higher
Prevalence of stunting and relationship between stunting and associated risk factors with academic achievement and cognitive function: a... (Publications)
stunted (95% CI: 7.6–10.8%). Low dietary diversity (β = 0.13, p = 0.004), food insecurity (β = −0.12, p = 0.034), and stunting (β = −0.13, p = 0.031) were associated with poorer end of the year results
