Improved outcome for very low birth weight multiple births (Publications)
analysis of covariance P = 0.007. The prevalence of cerebral palsy decreased, however not significantly adjusted odds ratio (95% confidence interval) 0.3 (0.1-1.5), P = 0.14. The proportion of disease-free [...] survival (no cerebral palsy and no developmental delay) increased for multiple births (7-37%, P = 0.002), but not for singletons. In cohort 2, neurodevelopmental outcome of multiple births was similar
A single FLOTAC is more sensitive than triplicate Kato-Katz for the diagnosis of low-intensity soil-transmitted helminth infections (Publications)
agreement between a single FLOTAC and triplicate Kato-Katz was 0.63 for diagnosing A. lumbricoides and 0.50 for T. trichiura, but only 0.30 for hookworm. The high sensitivity of FLOTAC holds promise for [...] hookworm and A. lumbricoides was 88.7, 83.0 and 82.8%, respectively. Lower sensitivities were observed for Kato-Katz even after examining three stool samples: 71.8, 46.0 and 70.3%, respectively. Kato-Katz revealed
Sleepless night, the moon is bright: longitudinal study of lunar phase and sleep (Publications)
h 00 min at new moon (P < 0.001). Average sleep duration was shortened by 68 min during the week compared with weekends (P < 0.001). Men slept 17 min longer than women (P < 0.001) and sleep duration decreased [...] decreased with age (P < 0.001). There was also evidence that rating of fatigue in the morning was associated with moon phase, with more tiredness (P = 0.027) at full moon. The study was designed for other
Changing patterns of health in communities impacted by a bioenergy project in northern Sierra Leone (Publications)
(all p < 0.05) and non-significantly at control sites. Anemia in children and in women of reproductive age (15-49 years) decreased significantly at impacted and control sites (p < 0.05 and p < 0.001, re [...] respectively). Health facility-based deliveries increased significantly at the impacted sites (p < 0.05). The prevalences of helminth infections in children aged 10-15 years remained approximately at the [...] increases at the impacted sites were noted. Access to improved sanitation...
Activity of tribendimidine and praziquantel combination therapy against the liver fluke <em>Opisthorchis viverrini</em> <em>in vitro</em> and <em>in... (Publications)
ne-praziquantel combinations against O. viverrini in vitro and in vivo. The IC50 values of 0.16 mug/ml and 0.05 mug/ml were determined for praziquantel and tribendimidine, respectively, against adult O [...] (combination index (CI) at the IC50 = 0.7). A similar result was observed when drug addition in vitro was spaced by the respective half-lives of the drugs (a CI of 0.78 at the IC50 for tribendimidine followed [...] followed by praziquantel and a CI of 0.47 at the IC50 for praziquantel...
Poor validity of noninvasive hemoglobin measurements by pulse oximetry compared with conventional absorptiometry in children in Côte d'Ivoire (Publications)
noninvasive measurements. A Bland-Altman analysis demonstrated a median bias of +1.1 g/dL (IQR = 0.4-2.0 g/dL), with greater overestimation of Hb by noninvasive testing occurring at low Hb values. This [...] and school-aged children, and both sexes. The Pearson correlation coefficient was 0.50 for children 4-9 years of age, and 0.33 for children 10-15 years of age. Further study and development of noninvasive [...] children 2-15 years of age and obtained in 102 (53.5%) children. The median Hb...
Socioeconomic disparities in childhood cancer survival in Switzerland (Publications)
different SES indicators, comparing the highest with the lowest group, ranged from 0.48 (95%CI: 0.28-0.81) to 0.71 (95%CI: 0.44-1.15). We conclude that even in Switzerland with a high quality health care system
The interspecific competition between larvae of <em>Aedes aegypti</em> and major african malaria vectors in a semi-field system in Tanzania (Publications)
density combinations of 100:100, 200:0, and 0:200 (Ae. aegypti: Anopheles), reared with and without food, in small habitats (8.5 cm height × 15 cm diameter) with 0.5 liters of water and large habitats [...] cm height × 35 cm diameter) with 1 liter of water. The first group received Tetramin(®) fish food (0.02 g), while the second group was unfed to assess cannibalism and predation. While interspecific competition [...] wing lengths of all species were significantly small in small habitats with a...
The risk of malarial infections and disease in Papua New Guinean children (Publications)
malaria (0.06/year). Children greater than nine years of age had a reduced risk of acquiring P. vivax infections of low-to-moderate (> 150/microL) density (adjusted hazard rate [AHR] = 0.65 and 0.42), whereas [...] of P. falciparum infection was only seen for parasitemias > 5,000/microL (AHR = 0.49) and symptomatic episodes (AHR = 0.51). Infection and symptomatic episodes with P. malariae and P. ovale were rare.
Effect of combinations of marketed human anthelmintic drugs against <em>Trichuris muris</em> <em>in vitro</em> and <em>in vivo</em> (Publications)
tin (Combination index (CI)=0.16), mebendazole-levamisole (CI=0.17) and albendazole-mebendazole (CI=0.23). For albendazole-ivermectin, moderate synergism was observed (CI=0.81) and for albendazole-levamisole [...] amisole a nearly additive effect was documented (CI=0.93) in vivo. Five combinations (albendazole-pyrantel pamoate, mebendazole-pyrantel pamoate, levamisole-pyrantel pamoate, levamisole-ivermectin and