Antiprotozoal activity-based profiling of a dichloromethane extract from <em>Anthemis nobilis</em> flowers (Publications)
against Trypanosoma brucei rhodesiense and Leishmania donovani, with IC50 values of 1.43 +/- 0.50 and 1.40 +/- 0.07 mug/mL, respectively. A comprehensive profiling of the most active fractions afforded 19 [...] showed high potency and selectivity in vitro against T. b. rhodesiense bloodstream forms (IC50 0.08 +/- 0.01 muM; SI 63). In silico calculations were consistent with the drug-like properties of 15.
Three-year rates of reoperation and revision following mobile versus fixed-bearing total ankle arthroplasty: a cohort of 302 patients with 2 implants... (Publications)
confidence interval [CI], 0.67 to 3.00; p = 0.36); for component revision, 3.31 (95% CI, 0.93 to 11.79; p = 0.06); and for metal component revision, 2.78 (95% CI, 0.58 to 13.33; p = 0.20). A total of 31 re [...] reoperations were performed in the mobile-bearing group compared with 14 in the fixed-bearing group (p = 0.07). More extensive reoperation procedures were performed in the mobile-bearing group. CONCLUSIONS:
The effect of community-driven larval source management and house improvement on malaria transmission when added to the standard malaria control... (Publications)
to the four trial arms. The mean nightly EIR fell from 0.010 infectious bites per person (95% CI 0.006-0.015) in the baseline year to 0.001 (0.000, 0.003) in the last year of the trial. Over the full trial [...] trial period, the EIR did not differ between the four trial arms (p = 0.33). Similar results were observed for the other outcomes: mosquito density and P. falciparum prevalence decreased over 3 years of
Agreement between parent and child report on parental practices regarding dietary, physical activity and sedentary behaviours: the ENERGY... (Publications)
(kappa) = 0.14) or watching TV (30%; kappa = 0.17), and for parental allowance of the child to have soft drinks (32%; kappa = 0.24) or fruit juices (32%; kappa = 0.19), or to watch TV (27%; kappa = 0.17). Having [...] in the child's bedroom were the only practices with moderate to good agreement (> 60%; kappa = 0.06 and 0.77, respectively). In general, agreement was lower for boys, younger children, younger parents
Dynamic assessment of right ventricular volumes and function by real-time three-dimensional echocardiography: a comparison study with magnetic... (Publications)
to 32.9 mL) for end-systolic volume, r = 0.77 (mean difference, 5.7 mL; 95% CI, -24.6 to 36.0 mL) for stroke volume, and r = 0.72 (mean difference, 0.4%; 95% CI, -14.2% to 15.1%) for ejection fraction. [...] coefficients on Bland-Altman analysis were r = 0.84 (mean difference, 10.2 mL; 95% confidence interval [CI], -31.3 to 51.7 mL) for end-diastolic volume, r = 0.83 (mean difference, 4.5 mL; 95% CI, -23.8 to [...] End-diastolic, end-systolic, and stroke volumes were slightly lower on RT3DE...
The production and antiprotozoal activity of abietane diterpenes in <em>Salvia austriaca</em> hairy roots grown in shake-flasks and bioreactor (Publications)
and 0.27). Other diterpenoids demonstrated weaker activity against tested parasites (IC50 values ranging from 0.62 to 194.7 microM) and lower selectivity (SI value ranged from 0.4 to 5.0). [...] (IC50 = 0.05 microM with high selectivity, SI = 38). Taxodione was found to inhibit the growth of P. falciparum and T. cruzi by 50% at respective concentrations of 1.9 and 7.1 microM, (SI values of 1.0 and [...] L-1), 15-deoxy-fuerstione (2.15 mg g-1 DW; equivalent to 32.5 mg L-1) and...
Three-year rates of reoperation and revision following mobile versus fixed-bearing total ankle arthroplasty: a cohort of 302 patients with 2 implants... (Publications)
confidence interval [CI], 0.67 to 3.00; p = 0.36); for component revision, 3.31 (95% CI, 0.93 to 11.79; p = 0.06); and for metal component revision, 2.78 (95% CI, 0.58 to 13.33; p = 0.20). A total of 31 re [...] reoperations were performed in the mobile-bearing group compared with 14 in the fixed-bearing group (p = 0.07). More extensive reoperation procedures were performed in the mobile-bearing group. CONCLUSIONS:
The effect of community-driven larval source management and house improvement on malaria transmission when added to the standard malaria control... (Publications)
to the four trial arms. The mean nightly EIR fell from 0.010 infectious bites per person (95% CI 0.006-0.015) in the baseline year to 0.001 (0.000, 0.003) in the last year of the trial. Over the full trial [...] trial period, the EIR did not differ between the four trial arms (p = 0.33). Similar results were observed for the other outcomes: mosquito density and P. falciparum prevalence decreased over 3 years of
Agreement between parent and child report on parental practices regarding dietary, physical activity and sedentary behaviours: the ENERGY... (Publications)
(kappa) = 0.14) or watching TV (30%; kappa = 0.17), and for parental allowance of the child to have soft drinks (32%; kappa = 0.24) or fruit juices (32%; kappa = 0.19), or to watch TV (27%; kappa = 0.17). Having [...] in the child's bedroom were the only practices with moderate to good agreement (> 60%; kappa = 0.06 and 0.77, respectively). In general, agreement was lower for boys, younger children, younger parents
Dynamic assessment of right ventricular volumes and function by real-time three-dimensional echocardiography: a comparison study with magnetic... (Publications)
to 32.9 mL) for end-systolic volume, r = 0.77 (mean difference, 5.7 mL; 95% CI, -24.6 to 36.0 mL) for stroke volume, and r = 0.72 (mean difference, 0.4%; 95% CI, -14.2% to 15.1%) for ejection fraction. [...] coefficients on Bland-Altman analysis were r = 0.84 (mean difference, 10.2 mL; 95% confidence interval [CI], -31.3 to 51.7 mL) for end-diastolic volume, r = 0.83 (mean difference, 4.5 mL; 95% CI, -23.8 to [...] End-diastolic, end-systolic, and stroke volumes were slightly lower on RT3DE...
