The production and antiprotozoal activity of abietane diterpenes in <em>Salvia austriaca</em> hairy roots grown in shake-flasks and bioreactor (Publications)
and 0.27). Other diterpenoids demonstrated weaker activity against tested parasites (IC50 values ranging from 0.62 to 194.7 microM) and lower selectivity (SI value ranged from 0.4 to 5.0). [...] (IC50 = 0.05 microM with high selectivity, SI = 38). Taxodione was found to inhibit the growth of P. falciparum and T. cruzi by 50% at respective concentrations of 1.9 and 7.1 microM, (SI values of 1.0 and [...] L-1), 15-deoxy-fuerstione (2.15 mg g-1 DW; equivalent to 32.5 mg L-1) and...
Evaluation of the fluorescence polarization assay as a rapid on-spot test for ruminant brucellosis in Côte d'Ivoire (Publications)
intra-test agreement (Kappa = 0.41). The agreement improved when the doubtful category was treated as negative (Kappa = 0.65), and when cattle were excluded (Kappa = 0.56 to 0.61). The RBT was performed on [...] indicated poor agreement (Kappa = 0.00); this improved to slight when only samples taken at the livestock market and tested in the laboratory were considered (Kappa = 0.14). The FPA did not perform well
Concurrent spatiotemporal daily land use regression modeling and missing data imputation of fine particulate matter using distributed space-time... (Publications)
R-squared was 0.73 and the average CV R-squared of 2-block and 5-block cross-validations was 0.60. These values were 0.68 and 0.47 when the spatial aspect of the LUR model was assessed, and 0.995 and 0.992 when
Doxycycline responding illnesses in returning travellers with undifferentiated non-malaria fever: a European multicenter prospective cohort study (Publications)
95%CI 4.85-322.18). Features of dengue such as retro-orbital pain (aOR 0.40, 95%CI 0.21-0.76) and neutropenia (aOR 0.41, 95%CI 0.21-0.79) were negatively associated with DRI. CONCLUSIONS: Although DRI are
Cross-validation of bioelectrical impedance analysis for the assessment of body composition in a representative sample of 6- to 13-year-old children (Publications)
(RMSE)=0.90 (95% CI 0.82-0.98) vs 1.12 kg (1.01-1.24); limits of agreement 1.80 to -1.80 kg vs 2.24 to -2.24 kg). 8-BIA also gave accurate estimates of appendicular body composition, with RMSE < or = 0.10 [...] 10 kg for arms and < or = 0.24 kg for legs. All external 4-BIA algorithms performed poorly with substantial negative proportional bias (r> or = 0.48, P
Levels of physical activity and sedentary time among 10- to 12-year-old boys and girls across 5 European countries using accelerometers: an... (Publications)
and PA according to gender and country. METHODS: 686 children (mean age = 11.6 +/- 0.8 years, 53% girls, mean BMI = 19.0 +/- 3.4 kg/m2) from Belgium, Greece, Hungary, the Netherlands and Switzerland wore [...] respectively; p < 0.001). 4.6% of the girls and 16.8% of the boys met moderate-to-vigorous PA recommendations of at least 60 minutes/day. Greek boys were more sedentary (510 minutes/day; all at p < 0.05) than other [...] girls were less sedentary (457 minutes/day; all at p < 0.05) than...
A Kiswahili version of the SF-36 Health Survey for use in Tanzania: translation and tests of scaling assumptions (Publications)
ranged from 0.47 to 0.81 for the entire sample. Median scaling success rates were 100% (range 87.5- 100.0). The median internal consistency reliability of the eight scales for the entire sample was 0.81 (range [...] (range 0.70-0.92). Floor effects were low and ceiling effects were high on five of the eight scales. Results for n = 402 people without formal education did not differ substantially from those of the entire
Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania - an emerging public health concern (Publications)
odds of VF. CD4 T cell percentage [OR = 0.20; 0.10-0.40 per additional 10%] and older age at ART initiation [OR = 0.84per additional year-of-age; 95%CI 0.73 to 0.97] were protective (also in predicting
Air pollution and atherosclerosis: a cross-sectional analysis of four European cohort studies in the ESCAPE study (Publications)
estimated increase in CIMT (geometric mean) of 0.72% (95% Confidence Interval [CI]: -0.65%, 2.10%) per 5 microg/m3 increase in PM2.5 and 0.42% (95% CI: -0.46%, 1.30%) per 10-5/m increase in PM2.5abs. Living [...] analyses. In an extended meta-analysis for PM2.5 with three other previously published studies, a 0.78% (95% CI: -0.18%, 1.75%) increase in CIMT was estimated for a 5 microg/m3 contrast in PM2.5. CONCLUSIONS:
Transient hyperglycemia in patients with tuberculosis in Tanzania: implications for diabetes screening algorithms (Publications)
(aOR(95% CI) at enrolment vs follow-up: FCG 9.6(3.7-24.7) vs 2.4(0.7-8.7); 2-hCG 6.6(4.0-11.1) vs 1.6(0.8-2.9); HbA1c 4.2(2.9-6.0) vs 1.4(0.9-2.0)). FCG hyperglycemia at enrolment was associated with TB treatment
