Transient hyperglycemia in patients with tuberculosis in Tanzania: implications for diabetes screening algorithms (Publications)
(aOR(95% CI) at enrolment vs follow-up: FCG 9.6(3.7-24.7) vs 2.4(0.7-8.7); 2-hCG 6.6(4.0-11.1) vs 1.6(0.8-2.9); HbA1c 4.2(2.9-6.0) vs 1.4(0.9-2.0)). FCG hyperglycemia at enrolment was associated with TB treatment
Particulate matter and subclinical atherosclerosis: associations between different particle sizes and sources with carotid intima-media thickness in... (Publications)
and 90th percentile was 1.58% (95% CI: -0.30, 3.47%) for PM10, 2.10% (95% CI: 0.04, 4.16%) for PM2.5, 1.67% (CI: -0.13, 3.48%) for the vehicular source of PM2.5, -0.58% (95% CI: -3.95, 2.79%) for the crustal [...] crustal source of PM2.5, 2.06% (95% CI: 0.03, 4.10%) for PNC, and 2.32% (95% CI: 0.23, 4.40%) for LDSA. Stronger associations were observed among diabetics, subjects with low educational level and those
Is age at menopause increasing across Europe? Results on age at menopause and determinants from two population-based studies (Publications)
activity (HR, 1.37; 95%, CI, 1.12-1.67). The determinant for later menopause was multiparity (HR, 0.74; 95% CI, 0.62-0.89). Predictors were similar for naturally and surgically induced menopause. Oral contraceptive [...] ous effects on timing of menopause. Later birth was associated with later menopause (HR, 0.934; 95% CI, 0.91-0.96). This evidence of a secular trend is heterogeneous across countries. CONCLUSIONS: Age
Diagnostic accuracy of the InBios Scrub Typhus DetectTM ELISA for the detection of IgM antibodies in Chittagong, Bangladesh (Publications)
a specificity (Sp) of 92.4 (95% CI: 95.0(-)89.0), while for convalescent samples the OD cut-off was > /=1.50 with Sn of 66.0 (95% CI: 78.5(-)51.7) and Sp of 96.0 (95% CI: 98.3(-)92.3). Comparisons against [...] cut-off OD to be within the range of 0.75(-)1.25. For admission samples, the best Sn/Sp compromise was at 1.25 OD (Sn 91.5%, Sp 92.4%) and for convalescent samples at 0.75 OD (Sn 69.8%, Sp 89.5%). A relatively
Bovine leptospirosis in abattoirs in Uganda: molecular detection and risk of exposure among workers (Publications)
= 3, p-value 0.003), exotic versus local breeds (OR = 21.3, p-value 0.002) or cattle from Western Uganda (OR = 4.4, p-value 0.001) and from regions across the border (OR = 3.3, p-value 0.032) versus from [...] urine) positive carcass ranged from 27% (95% credibility interval 18.6-52.3) to 100% (95% CI 91.0-100.0), with halal butchers and pluck inspectors being at highest risk. In conclusion, cattle slaughtered
Evaluation of the fluorescence polarization assay as a rapid on-spot test for ruminant brucellosis in Côte d'Ivoire (Publications)
intra-test agreement (Kappa = 0.41). The agreement improved when the doubtful category was treated as negative (Kappa = 0.65), and when cattle were excluded (Kappa = 0.56 to 0.61). The RBT was performed on [...] indicated poor agreement (Kappa = 0.00); this improved to slight when only samples taken at the livestock market and tested in the laboratory were considered (Kappa = 0.14). The FPA did not perform well
Concurrent spatiotemporal daily land use regression modeling and missing data imputation of fine particulate matter using distributed space-time... (Publications)
R-squared was 0.73 and the average CV R-squared of 2-block and 5-block cross-validations was 0.60. These values were 0.68 and 0.47 when the spatial aspect of the LUR model was assessed, and 0.995 and 0.992 when
Delay in diagnosis of pulmonary tuberculosis increases the risk of pulmonary cavitation in pastoralist setting of Ethiopia (Publications)
delay [P < 0.001]; 22.2% among patients diagnosed within 30 days of illness and 51.7% if delay was over 30 days. The threshold delay that optimizes cavitation was 43 days [AUC (95% CI) = 0.67(0.62-0.72)]. Smear [...] Smear positivity was significantly increased in patients delayed over 49 days [p = 0.02]. Other factors associated with cavitation were age
Synthesis, <em>in-vitro</em> antiprotozoal activity and molecular docking study of isothiocyanate derivatives (Publications)
Leishmania donovani with IC50 values between 0.4 and 1.0microM and selectivity index (SI) ranged from 7.8 to 18.4, comparable to the standard drug miltefosine (IC50=0.7muM). Compound 7h demonstrated the best [...] antileishmanial activity with an IC50 value of 0.4microM. Seven products exhibited inhibition activity against T. brucei rhodesiense with IC50s below 2.0muM and SI between 2.7 and 29.3. Four primary amine
Associations of partner age gap at sexual debut with teenage parenthood and lifetime number of partners (Publications)
a partner age gap of 3-4 years (odds ratio, 1.8) or more (2.0); they were reduced if debut occurred before age 15 and the gap was 3-4 years (0.8). Females' likelihood of reporting a high lifetime number [...] number of partners was negatively associated with age gap (0.4-0.7, depending on age at debut and length of age gap). Males' likelihood of reporting a large number of partners was positively associated with [...] and the gap was five or more years (1.7) or if debut was at ages 15-17...
