Antiplasmodial lanostanes from the <em>Ganoderma lucidum</em> mushroom (Publications)
yielded seven lanostanes (1-7), of which three (2, 3, and 7) were new. A new benzofuran derivative (8) of the farnesyl hydroquinone ganomycin B was also identified. The structures and relative configurations
Six naphthylisoquinoline alkaloids and a related benzopyranone from a Congolese <em>Ancistrocladus</em> species related to <em>Ancistrocladus... (Publications)
ancistrobertsonine C (7), have been isolated, along with a likewise benzopyranone carboxylic acid, 8. The structural elucidation succeeded by chemical, spectroscopic, and chiroptical methods. Their bi
Antiplasmodial lanostanes from the <em>Ganoderma lucidum</em> mushroom (Publications)
yielded seven lanostanes (1-7), of which three (2, 3, and 7) were new. A new benzofuran derivative (8) of the farnesyl hydroquinone ganomycin B was also identified. The structures and relative configurations
Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global... (Publications)
(14·8 to 18·4) in children younger than 5 years, 16·2% (14·2 to 17·9) in those aged 5-14 years, 6·29% (5·05 to 7·70) in those aged 15-49 years, 5·72% (4·02 to 7·39) in those aged 50-69 years, and 8·48% [...] available cause-specific mortality data. FINDINGS: We estimated 9·40 million (95% uncertainty interval [UI] 8·36 to 10·5) tuberculosis incident cases and 1·35 million (1·23 to 1·52) deaths due to tuberculosis in [...] 1·39 million (1·28 to 1·54) to 1·00 million (0·703 to 1·23) in 2020,...
Phototemtide A, a cyclic lipopeptide heterologously expressed from<em> Photorhabdus temperata </em>Meg1, shows selective antiprotozoal activity (Publications)
de A (1) showed weak antiprotozoal activity against Plasmodium falciparum, with an IC50 value of 9.8 mum. The biosynthesis of phototemtides A-D (1-4) was also proposed.
Case report: Diagnostic challenges in the detection of a mixed <em>Plasmodium vivax/ovale</em> infection in a non-endemic setting (Publications)
diagnostic test, as a low number of parasites of one species may occur. Here, we report the case of an 8-year-old girl migrating with her family from Afghanistan with a two-species mixed infection with Plasmodium
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis (Publications)
than non-users. Amodiaquine was associated with a 3.1-times increased risk (95% confidence limits 1.8-5.4) of abnormal SGPT values. We consider toxic products, including metabolites of amodiaquine, the
Impact of social accountability monitoring on health facility performance: evidence from Tanzania (Publications)
in program exposure in Tanzania. We find that the social accountability intervention resulted in a 1.8 SD reduction in drug stockouts relative to the control group, but did not improve facility infrastructure
Medicaid family planning waivers in 3 states: did they reduce unwanted births? (Publications)
associated with almost a 5.0 percentage point reduction in unwanted births among adults and with a 7 to 8.0 percentage point reduction, among youth less than 21 years of age. Oregon's waiver was associated
Quality of drinking-water at source and point-of-consumption-drinking cup as a high potential recontamination risk: a field study in Bolivia (Publications)
[median=0 colony-forming unit (CFU)/100 mL, interquartile range (IQR: 0-13)] to the drinking cup (median=8 CFU/100 mL; IQR: 0-550; n= 81, z=-3.7, p
