Development and evaluation of a multiplex quantitative real-time polymerase chain reaction for hookworm species in human stool (Publications)
evaluated using DNA extracted from 192 fecal samples collected as part of a soil-transmitted helminth (STH) survey in northern Cambodia. The prevalence of hookworms as detected by the multiplex hookworm qPCR [...] detection of both N. americanus (Kappa 0.943) and Ancylostoma spp. (Kappa 0.936) with a multiplex STH qPCR. A strong and moderate quantitative correlation between cycle threshold and eggs per gram (EPG)
Efficacy and safety of ascending dosages of moxidectin and moxidectin-albendazole against <em>Trichuris trichiura</em> in adolescents: a randomized... (Publications)
BACKGROUND: Preventive chemotherapy is the main strategy to control soil-transmitted helminth (STH) infections. Albendazole and Mebendazole are ubiquitously used but they are not sufficiently effective [...] mg plus 400 mg should be investigated further to develop recommendations for appropriate control of STH infections. Trial Registration: The trial is registered at clinicaltrial.gov, number NCT03501251.
Efficacy and safety of ascending dosages of moxidectin and moxidectin-albendazole against <em>Trichuris trichiura</em> in adolescents: a randomized... (Publications)
BACKGROUND: Preventive chemotherapy is the main strategy to control soil-transmitted helminth (STH) infections. Albendazole and Mebendazole are ubiquitously used but they are not sufficiently effective [...] mg plus 400 mg should be investigated further to develop recommendations for appropriate control of STH infections. Trial Registration: The trial is registered at clinicaltrial.gov, number NCT03501251.
Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with <em>Trichuris trichiura</em>:... (Publications)
concomitant soil-transmitted helminth (STH) infections (Ascaris lumbricoides, hookworm and Strongyloides stercoralis) and egg reduction rates (ERRs) against STH at 14-21 days, 180 days and 360 days. T
Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with <em>Trichuris trichiura</em>:... (Publications)
concomitant soil-transmitted helminth (STH) infections (Ascaris lumbricoides, hookworm and Strongyloides stercoralis) and egg reduction rates (ERRs) against STH at 14-21 days, 180 days and 360 days. T
Efficacy and safety of albendazole alone versus albendazole in combination with ivermectin for the treatment of <em>Trichuris trichiura</em>... (Publications)
Trichuris trichiura, a soil-transmitted helminth (STH), often persists after a single dose of anthelminthic treatment. To overcome limited efficacy against T. trichiura of benzimidazoles (albendazole or [...] high ERRs observed albendazole-ivermectin might aid in eliminating morbidity, an important target of STH control programs. Trial registration (clinicaltrials.gov): NCT06037876.
Estimating prevalence and infection intensity of soil-transmitted helminths using quantitative polymerase chain reaction and Kato-Katz in school-age... (Publications)
helminth (STH) diagnostics, especially for Strongyloides stercoralis and differentiating hookworm species. However, sample preservation and DNA extraction may influence qPCR performance. We estimated STH prevalence
Estimating prevalence and infection intensity of soil-transmitted helminths using quantitative polymerase chain reaction and kato-katz in school-age... (Publications)
helminth (STH) diagnostics, especially for Strongyloides stercoralis and differentiating hookworm species. However, sample preservation and DNA extraction may influence qPCR performance. We estimated STH prevalence
infections are a major public health issue in low and middle-income countries. Soil-transmitted helminth (STH) infections affect 1.5 billion people globally. They are caused by different species of parasitic worms [...] in areas where sanitation is poor. Two main drugs - albendazole and mebendazole – are used to treat STH as preventive chemotherapy. They have been used for many years both in human and veterinary medicine [...] chemotherapy programmes. Tribendimidine has to date only been...
communities in low- and middle-income countries. The global strategy to control morbidity due to STH infections is preventive chemotherapy (PC) with one of the two benzimidazole drugs (albendazole and [...] Assembling and generating the evidence to inform recommendations on co-administration of drugs in STH control programs will be done with two activities. First, we will systematically review and analyze
