Particulate matter composition and respiratory health: the PIAMA birth cohort study (Publications)
(change [95% confidence interval] -2.1% [-1.1, -0.1%] and -1.0% [-2.0, -0.0%]) and FEF75-50 with copper in PM10 at the current address (-2.3% [-4.3, -0.3%]). CONCLUSION:: PM constituents, in particular
Community-owned resource persons for malaria vector control: enabling factors and challenges in an operational programme in Dar es Salaam, United... (Publications)
(Odds Ratio = 0.660, 95% confidence interval = [0.438, 0.995], P = 0.047). Staff living within their areas of responsibility had > 70% higher detection sensitivity for both Anopheline (P = 0.016) and Culicine [...] Culicine (P = 0.012): positive habitats compared to those living outside those same areas. DISCUSSION AND CONCLUSIONS: Improved employment conditions as well as involving the local health committees in
Long-term outcomes in mild/moderate chronic obstructive pulmonary disease in the European community respiratory health survey (Publications)
105 (2.0%) subjects had the same ratio less than 0.70 (modified GOLD-COPD). At follow-up, smokers with LLN-COPD (n = 205) had a greater mean DeltaFEV(1)% (1.7%; 95% confidence interval [CI], 0.8-2.7) and [...] normal subjects. Similarly, symptomatic subjects with LLN-COPD (n = 104) had DeltaFEV(1)% (2.0%; 95% CI, 0.8-3.3) and the hospitalization rate (RR, 4.18; 95% CI, 2.43-7.21) higher than the reference group [...] with LLN-COPD, the association of symptoms with DeltaFEV(1)% varied according...
Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study (Publications)
within 500 m of a freeway, with mean percent-predicted 97.0% for FEV1 (p=0.013, relative to > 1500 m [95% CI 94.6-99.4]) and 93.4% for MMEF (p=0.006 [95% CI 89.1-97.7]). INTERPRETATION: Local exposure to [...] growth of forced expiratory volume in 1 s (FEV(1), -81 mL, p=0.01 [95% CI -143 to -18]) and maximum midexpiratory flow rate (MMEF, -127 mL/s, p=0.03 [-243 to -11), compared with children who lived at least [...] 8-year lung-function growth. METHODS: In this prospective study, 3677 children...
Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II) (Publications)
1.3-4.0, p=0.007). Asthma risk was also increased in participants who reported an acute symptomatic inhalation event such as fire, mixing cleaning products, or chemical spills (RR=3.3, 95% CI 1.0-11.1, [...] asthma (Relative risk=1.6, 95% CI 1.1-2.3, p=0.017). Risks were highest for asthma defined by bronchial hyper-reactivity in addition to symptoms (2.4, 1.3-4.6, p=0.008). Of common occupations, a significant [...] p=0.051). The population-attributable risk for adult asthma due to...
Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study (Publications)
enrolled for low dose (median: 2.4 GBq/cycle, range 0.9-7.8 GBq/cycle), 77 patients were enrolled for intermediate dose (median: 3.3 GBq/cycle, range: 2.0-7.4 GBq/cycle) and 222 patients were enrolled for [...] The incidences of hematotoxicities grade 1--4 were 65.0%, 64.9% and 74.8%; the incidences of grade 4/5 kidney toxicities were 8.4%, 6.5% and 14.0%, and the median survival was 39 (range: 1--158) months [...] (Hazard Ratio: 3.12 (1.13-8.59) vs. intermediate dose, p = 0.03) and a shorter...
NY-BR-1 protein expression in breast carcinoma: a mammary gland differentiation antigen as target for cancer immunotherapy (Publications)
carcinomas (P < 0.0001). Moreover, NY-BR-1 expression correlated directly with estrogen receptor expression (P < 0.0001) and inversely correlated with HER2-status and EGFR expression (P < 0.0001 for both) [...] chemotherapy suggest that NY-BR-1 expression is not influenced by preceding chemotherapy (kappa = 0.89, P < 0.0001). In summary, the co-expression of NY-BR-1 with HLA class I antigens and its expression in [...] patients. Survival analysis showed an association of NY-BR-1 expression with...
Risk factors for Buruli ulcer in Ghana - a case control study in the Suhum-Kraboa-Coaltar and Akuapem south districts of the eastern region (Publications)
associated with BU. Rubbing an injured area with alcohol (OR = 0.21, 95% CI = 0.008-0.57) and wearing long sleeves for farming (OR = 0.29, 95% CI = 0.14-0.62) showed protection against BU. CONCLUSION: This study
Effect of a governmentally-led physical activity program on motor skills in young children attending child care centers: a cluster randomized... (Publications)
no significant increase in motor skills (delta of mean change (95% confidence interval: -0.2 (-0.8 to 0.3), p = 0.43) or in any of the secondary outcomes. Not all child care centers implemented all the [...] assessed. RESULTS: At baseline, 648 children present on the motor test day were included (age 3.3 +/- 0.6, BMI 16.3 +/- 1.3 kg/m2, 13.2% overweight, 49% girls) and 313 received the intervention. Relative [...] 3) free-access to a movement space and purchase of mobile equipment for physical...
Air pollution and cardiovascular mortality with over 25 years follow-up: a combined analysis of two British cohorts (Publications)
models. Per 10mug/m3 increase HRs were 1.11 [95% CI: 0.76-1.61] for BS, 1.05 [95% CI: 0.91-1.22] for SO2, 1.16 [95% CI: 0.70-1.92] for PM10 and 1.30 [95% CI: 0.39-4.34] for PM2.5, with largest effects seen in [...] in the fourth quartile of BS and PM2.5 compared to the first with HR 1.24 [95% CI: 0.91-1.61] and 1.21 [95% CI: 0.88-1.66] respectively. There were no consistent associations with other ESCAPE pollutants
