Predicted temperature-increase-induced global health burden and its regional variability (Publications)
C/100ppm) and Finland (1.14 degrees C/100ppm), while it is smallest in Ireland (0.62 degrees C/100ppm) and Argentina (0.63 degrees C/100ppm). In addition, for each 1 degrees C temperature increase, the [...] degrees C) and the Philippines (8.18%p/ degrees C), while it is decreased in Ireland (-0.92%p/ degrees C) and Australia (-0.32%p/ degrees C). To understand the regional variability in temperature increase and
Myeloperoxidase, but not oxidized LDL, is associated with leisure-time physical activity: results from the MONICA/KORA Augsburg Studies 1984-1995 (Publications)
leisure-time PA (124.2 mug/ml; 95%-CI, 116.8-132.0) compared to the inactive reference group (133.5 mug/ml; 95%-CI, 127.6-139.6) (P(trend) across PA levels: 0.007). No significant association between ox-LDL [...] ox-LDL and PA domains was observed (P(trend) between 0.162 and 0.803). CONCLUSION: These data indicate that regular leisure-time PA may reduce MPO concentrations
Abietane diterpenoids from <em>Salvia sahendica</em> - antiprotozoal activity and determination of their absolute configurations (Publications)
compounds ranged from 0.8 microM to over 8.8 microM against P. falciparum, and from 1.8 microM to over 32.3 microM against T. brucei rhodesiense. The cytotoxic IC50 values ranged from 0.5-15.5 microM. Selectivity [...] Selectivity indices for P. falciparum were 0.1 to 18.2, and 0.1 to 1.2 for T. brucei rhodesiense
Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel... (Publications)
occurred in 39 of 544 (7.2%) patients with DES and 34 of 280 (12.1%) with BMS (odds ratio 0.56, 95% CI 0.35-0.91; p=0.02), without significant differences between the two DES. Total costs at 6 months were
Epidemiology of <em>Plasmodium falciparum</em> gametocytemia in India: prevalence, age structure, risk factors and the role of a predictive score for... (Publications)
The area under the receiver operator characteristic curve was 0.76 (95%CI:0.73,0.78), and a cut-off of 14 or more on a risk score ranging from 0 to 46 provided 91% (95%CI:88,95) sensitivity and 33% (95%CI:31
<em>In silico</em> prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against <em>Trypanosoma brucei... (Publications)
and 4,15-isoatriplicolide tiglate, were therefore tested. They displayed IC50 values of 0.07, 0.20 and 0.07 and 0.015 muM, respectively, so that the in silico-prediction was experimentally confirmed. 4
Antitrypanosomal isoflavan quinones from <em>Abrus precatorius</em> (Publications)
ECD data. Compounds 2 to 5 showed high in vitro activity against T. b. rhodesiense (IC50 of 0.01, 0.02, 0.02 and 0.01muM, respectively), and remarkable SIs of 508, 374, 1379, and 668, respectively
Myeloperoxidase, but not oxidized LDL, is associated with leisure-time physical activity: results from the MONICA/KORA Augsburg Studies 1984-1995 (Publications)
leisure-time PA (124.2 mug/ml; 95%-CI, 116.8-132.0) compared to the inactive reference group (133.5 mug/ml; 95%-CI, 127.6-139.6) (P(trend) across PA levels: 0.007). No significant association between ox-LDL [...] ox-LDL and PA domains was observed (P(trend) between 0.162 and 0.803). CONCLUSION: These data indicate that regular leisure-time PA may reduce MPO concentrations
Abietane diterpenoids from <em>Salvia sahendica</em> - antiprotozoal activity and determination of their absolute configurations (Publications)
compounds ranged from 0.8 microM to over 8.8 microM against P. falciparum, and from 1.8 microM to over 32.3 microM against T. brucei rhodesiense. The cytotoxic IC50 values ranged from 0.5-15.5 microM. Selectivity [...] Selectivity indices for P. falciparum were 0.1 to 18.2, and 0.1 to 1.2 for T. brucei rhodesiense
Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel... (Publications)
occurred in 39 of 544 (7.2%) patients with DES and 34 of 280 (12.1%) with BMS (odds ratio 0.56, 95% CI 0.35-0.91; p=0.02), without significant differences between the two DES. Total costs at 6 months were