Comparison of diagnostic methods for the detection and quantification of the four sympatric <em>Plasmodium</em> species in field samples from Papua... (Publications)
respectively. This compares to 43.8% and 73.2% by nPCR and 47.1% and 67.5% by PCR_LDR_FMA. P. malariae and P. ovale prevalence was 4.7% and 7.3% by qPCR, 3.3% and 3.8% by nPCR, and 7.7% and 4.4% by PCR_LDR_FMA
High sensitivity detection of <em>Plasmodium</em> species reveals positive correlations between infections of different species, shifts in age... (Publications)
001). Increases were particularly pronounced for P. malariae (3.9% vs 13.4%) and P. ovale (0.0% vs 4.8%). In contrast to LM diagnosis, which suggested a significant deficit of mixed species infections, a [...] species infection prevalence explaining between 60.6% - 74.5% of this variation for LDR-FMA and 81.8% - 90.0% for LM (except P. falciparum), respectively. CONCLUSION: The present study demonstrates that
Validation of a rhinitis symptom questionnaire (ISAAC core questions) in a population of Swiss school children visiting the school health services (Publications)
September) (OR = 4.9, 95% CI: 3.6-6.5) and a combination of these latter two symptoms (OR = 5.8, 95% CI: 4.1-8.1). The association was stronger for a sensitization to outdoor allergens than for indoor allergens
Response, survival, and long-term toxicity after therapy with the radiolabeled somatostatin analogue [90Y-DOTA]-TOC in metastasized neuroendocrine... (Publications)
months; P = .023), and clinical response (HR, 0.68; 95% CI, 0.56 to 0.82; 36.8 v 23.5 months; P < .001). Overall, 142 patients (12.8%) developed grade 3 to 4 transient hematologic toxicities, and 103 patients
Risk factors associated with the epilepsy treatment gap in Kilifi, Kenya: a cross-sectional study (Publications)
of self-reported adherence compared with AEDs detected in blood were 38.1% (95% CI 31.1-45.4) and 80.8% (76.0-85.0). The epilepsy treatment gap was 62.4% (58.1-66.6). In multivariable analysis, failure to [...] about biomedical treatment (0.86, 0.78-0.95), living more than 30 km from health facilities (3.89, 1.77-8.51), paying for AEDs (2.99, 1.82-4.92), having learning difficulties (2.30, 1.29-4.11), having had epilepsy
Local and foreign authorship of maternal health interventional research in low- and middle-income countries: systematic mapping of publications... (Publications)
1/year in 2008-2012. In the same periods, the proportion of papers led by a local author was 58.4 %, 60.8 % and 60.1 %, respectively. Data ownership varies markedly between countries. A quarter of countries [...] a local first author. Researchers at LMIC institutions led 56.6 % (1297) of all papers, but only 26.8 % of systematic reviews (65/243), 29.9 % of modelling studies (44/147), and 33.2 % of articles in journals
Wayanin and guaijaverin, two active metabolites found in a <em>Psidium acutangulum</em> Mart. ex DC (syn. P. persoonii McVaugh) (Myrtaceae)... (Publications)
antiplasmodial activity evaluated against chloroquine-resistant FcB1 ([3H]-hypoxanthine bioassay) and 7G8 (pLDH bioassay) P. falciparum strains, and on a chloroquine sensitive NF54 ([3H]-hypoxanthine bioassay) [...] compounds were tested on P. falciparum FcB1 strain. In vitro anti-inflammatory activity (IL-1beta, IL-6, IL-8, TNFalpha) of the ethyl acetate fraction and of an anti-Plasmodium active compound, was concurrently
Prevalence and seasonal transmission of <em>Schistosoma haematobium</em> infection among school-aged children in Kaedi town, southern Mauritania (Publications)
confidence interval (CI): 3.2-4.9%) with a geometric mean egg count per 10 ml of urine of 3.7 (95% CI: 2.8-4.3). Being male (adjusted odds ratio (aOR) 1.78, 95% CI: 1.13-2.80), being at primary school (aOR 1 [...] (n = 4983, 48.6%). The average time spent in the water per person per day was 14.2 min (95% CI: 13.8-14.6 min). The frequency and duration of water contact followed a seasonal pattern. CONCLUSION: Our
The burden of primary liver cancer and underlying etiologies from 1990 to 2015 at the global, regional, and national level: results from the Global... (Publications)
structures, 35% by population growth, and -8% to changing age-specific incidence rates. The male-to-female ratio for age-standardized liver cancer mortality was 2.8. Globally, HBV accounted for 265000 liver
The effect of case management and vector-control interventions on space-time patterns of malaria incidence in Uganda (Publications)
cases (95% CI 72.4-77.1) in 2013 to 49.4 (95% CI 42.9-55.8) per 1000 in 2015 and followed by an increase in 2016 of up to 51.3 (95% CI 42.9-55.8). In individuals > /= 5 years, a decline in incidence from
