Association of FEV1 in asthmatic children with personal and microenvironmental exposure to airborne particulate matter (Publications)
PM, -6.0% (-10.5 to -1.4); 30 microg/m3 24-hr average personal PM, -5.9% (-10.8 to -1.0); 6.7 microg/m3 indoor home PM2.5, -1.6% (-2.8 to -0.4); 16 microg/m3 indoor home PM10, -2.1% (-3.7 to -0.4); 7.1 [...] 1 microg/m3 outdoor home PM2.5, -1.1% (-2.4 to 0.1); and 7.5 microg/m3 central-site PM2.5, -0.7% (-1.9 to 0.4). Stronger associations were found for multiday moving averages of PM for both personal and
Pregnancy outcomes and risk of placental malaria after artemisinin-based and quinine-based treatment for uncomplicated falciparum malaria in... (Publications)
conducted. The risks of stillbirth (pregnancy loss at > /= 28.0 weeks of gestation), moderate to late preterm birth (PTB, live birth between 32.0 and < 37.0 weeks), small for gestational age (SGA, birthweight of [...] confidence interval [CI] 1.03 to 1.26, p = 0.009) and deposition of malaria pigment in the placenta (aOR 1.67 per 10-fold increase, 95% CI 1.42 to 1.96, p < 0.001). CONCLUSIONS: The risks of stillbirth [...] 3. RESULTS: Of the 22 eligible studies (n = 5015), IPD from16 studies were...
Burden of disease scenarios by state in the USA, 2022-50: a forecasting analysis for the Global Burden of Disease Study 2021 (Publications)
additional years (0·3-0·6) of life expectancy and 0·6 additional years (0·5-0·8) of HALE in 2050 under the improved drug use scenario relative to the reference scenario. Life expectancy and HALE are likewise projected [...] years (3·6-4·0) of life expectancy and 4·1 additional years (3·9-4·3) of HALE in 2050 versus the reference scenario. Using our USA-specific scenarios, we forecasted that the USA could gain 0·4 additional [...] projected to be 0·4-0·5 years higher in 2050 under the improved...
Quality of drinking-water at source and point-of-consumption-drinking cup as a high potential recontamination risk: a field study in Bolivia (Publications)
significantly from the water source [median=0 colony-forming unit (CFU)/100 mL, interquartile range (IQR: 0-13)] to the drinking cup (median=8 CFU/100 mL; IQR: 0-550; n= 81, z=-3.7, p
Quality of drinking-water at source and point-of-consumption-drinking cup as a high potential recontamination risk: a field study in Bolivia (Publications)
significantly from the water source [median=0 colony-forming unit (CFU)/100 mL, interquartile range (IQR: 0-13)] to the drinking cup (median=8 CFU/100 mL; IQR: 0-550; n= 81, z=-3.7, p
Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health... (Publications)
weak correlation among the three matrices (Rs = −0.12 to 0.35), except for chlorpyrifos in dust and its biomarker 3,5,6-trichloro-2-pyridinol in urine (Rs = 0.44). No differences in exposure levels between [...] targeted in urine, wristbands, and dust. Levels of chlorpyrifos in dust (ICC = 0.92) and diethylphosphate biomarker in urine (ICC = 0.42) showed strong and moderate temporal agreement between day 1 and day 7
Short-term effects of PM10, NO2, SO2 and O3 on cardio-respiratory mortality in Cape Town, South Africa, 2006-2015 (Publications)
and 15.6 µg/m3 O3 lag 0–1 were positively associated with CVD, with an increased risk of 2.4% (95% CI: 0.9–3.9%), 2.2 (95% CI: 0.4–4.1%), 1.4% (95% CI: 0–2.8%) and 2.5% (95% CI: 0.2–4.8%), respectively
Emergence of human immunodeficiency virus-1 drug resistance during the 3-month World Health Organization-recommended enhanced adherence counseling... (Publications)
to 36 of 57 (63.2%) after EAC. Median susceptibility scores dropped from 0.5 (interquartile range [IQR] = 0.25-) to 0.25 (IQR = 0.25-1) during the EAC period (P = .16). Conclusions: Despite high levels [...] and viral susceptibility scores to each participant's antiretroviral therapy (ART) regimen (range, 0-3; 3 indicates complete susceptibility). Results: Among 93 participants taking nonnucleoside revers
How are academic achievement and inhibitory control associated with physical fitness, soil-transmitted helminth infections, food insecurity and... (Publications)
achievement among boys (p < 0.05), whereas higher levels of cardiorespiratory fitness and not being stunted explained most variance in academic achievement in girls (p < 0.05). Higher age turned out to [...] performance in the Flanker task (p < 0.01). Additionally, in boys, higher grip strength was associated with better information processing and inhibitory control of attention (p < 0.01), whereas in girls, higher [...] higher cardiorespiratory fitness levels were positively associated with...
Validation of a human-serum-based <em>in vitro </em>growth method for drug screening on juvenile development stages of <em>Schistosoma mansoni</em> (Publications)
serum were similar in size as in vivo worms until 28 days of incubation (males 1.4 +/- 0.2 mm, females 1.1 +/- 0.5 mm long). qPCR analysis revealed similar gender distribution both on newly transformed [...] development, where a slightly lower activity was observed for the in vitro grown worms (IC50: 0.54 muM in vitro, 0.14 muM in vivo 72 hours post-incubation). The evaluation of five additional drugs revealed [...] sensitivity on in vitro developed schistosomes when compared to in vivo grown...
