Selamectin is the avermectin with the best potential for Buruli ulcer treatment (Publications)
Milbemycin oxime and selamectin were the most active drugs against M. ulcerans with MIC values from 2 to 8 mug/mL and 2 to 4 mug/mL, respectively. In contrast, ivermectin and moxidectin, which are both in clinical
The epidemiology of residual <em>Plasmodium falciparum</em> malaria transmission and infection burden in an African city with high coverage of... (Publications)
(P = 0.325) when managed by a private-sector contractor. Infection prevalence rebounded back to 13.8 % in 2010, compared with
Comparison of the Flotac-400 dual technique and the formalin-ether concentration technique for the diagnosis of human intestinal protozoa infection (Publications)
FLOTAC-400 dual technique (results from both FS combined) found higher prevalences of Entamoeba coli (77.8% vs. 71.3%, p
Assessment of breast cancer opportunistic screening by clinical-pathological indicators: a population-based study (Publications)
breast cancer were identified. The proportion of DCIS with respect to invasive cases increased from 5.8% in the period 1996-2001 to 6.4% in the period 2002-2007. The median tumour size of invasive cancers
<em>ent</em>-dioncophylleine A and related dehydrogenated naphthylisoquinoline alkaloids, the first Asian dioncophyllaceae-type alkaloids, from the... (Publications)
ent-dioncophylleine A (3a), the likewise 7,1'-coupled 5'-O-demethyl-ent-dioncophylleine A (4), and the 7,8'-linked dioncophylleine D (5), have been isolated from the leaves of the recently described Malaysian
Flow cytometric analysis on cross-reactivity of human-specific CD monoclonal antibodies with splenocytes of <em>Aotus nancymaae</em>, a non-human... (Publications)
(mAb) out of 377 commercially available antibodies collected by the animal homologue group of the HLAD8 was analyzed by single colour flow cytometry. Most of these mAb were originally developed against human
Jacaranone-derived glucosidic esters from Jacaranda glabra and their activity against <em>Plasmodium falciparum</em> (Publications)
generally possessed a low cytotoxicity toward L-6 cells, with the exception of compound 1 (IC(50) 1, 8.3; 2, > 90; 3, 87; and 4, 85 microg/mL)
Treatment of acute uncomplicated <em>Falciparum</em> malaria with artemether-lumefantrine in nonimmune populations: a safety, efficacy, and... (Publications)
population (119/124 patients). Median times to parasite clearance and fever clearance were 41.5 and 36.8 hours, respectively. No patient had gametocytes after Day 7. Treatment was well tolerated; most adverse
Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead... (Publications)
ydroxyphenylacetamide) (3), exhibited two orders of magnitude increased anti-P. f activity (IC(50) 8.6nM) with no detectable in vitro toxicity. The ease of synthesis of phenylacetamido-polyamines, coupled
Bisabololoxide derivatives from <em>Artemisia persica</em>, and determination of their absolute configurations by ECD (Publications)
exhibited in vitro antimalarial activity against Plasmodium falciparum, with IC(50) values ranging from 2.8 to 20.1muM, and selectivity indices (SI) in L-6 cells of 3.7-11.9
