Recovery of left ventricular systolic function in peripartum cardiomyopathy: an observational study from rural Tanzania (Publications)
(each 5% increase; OR 1.7, 95% CI 1.10-2.62, p = 0.012), while higher age was inversely associated (each 10 years increase; OR 0.40, 95% CI 0.19-0.82, p = 0.012). CONCLUSION: Left ventricular systolic function
Recovery of left ventricular systolic function in peripartum cardiomyopathy: an observational study from rural Tanzania (Publications)
(each 5% increase; OR 1.7, 95% CI 1.10-2.62, p = 0.012), while higher age was inversely associated (each 10 years increase; OR 0.40, 95% CI 0.19-0.82, p = 0.012). CONCLUSION: Left ventricular systolic function
Child exposure to organophosphate and pyrethroid insecticides measured in urine, wristbands, and household dust and its implications for child health... (Publications)
weak correlation among the three matrices (Rs = −0.12 to 0.35), except for chlorpyrifos in dust and its biomarker 3,5,6-trichloro-2-pyridinol in urine (Rs = 0.44). No differences in exposure levels between [...] targeted in urine, wristbands, and dust. Levels of chlorpyrifos in dust (ICC = 0.92) and diethylphosphate biomarker in urine (ICC = 0.42) showed strong and moderate temporal agreement between day 1 and day 7
Short-term effects of PM10, NO2, SO2 and O3 on cardio-respiratory mortality in Cape Town, South Africa, 2006-2015 (Publications)
and 15.6 µg/m3 O3 lag 0–1 were positively associated with CVD, with an increased risk of 2.4% (95% CI: 0.9–3.9%), 2.2 (95% CI: 0.4–4.1%), 1.4% (95% CI: 0–2.8%) and 2.5% (95% CI: 0.2–4.8%), respectively
Emergence of human immunodeficiency virus-1 drug resistance during the 3-month World Health Organization-recommended enhanced adherence counseling... (Publications)
to 36 of 57 (63.2%) after EAC. Median susceptibility scores dropped from 0.5 (interquartile range [IQR] = 0.25-) to 0.25 (IQR = 0.25-1) during the EAC period (P = .16). Conclusions: Despite high levels [...] and viral susceptibility scores to each participant's antiretroviral therapy (ART) regimen (range, 0-3; 3 indicates complete susceptibility). Results: Among 93 participants taking nonnucleoside revers
How are academic achievement and inhibitory control associated with physical fitness, soil-transmitted helminth infections, food insecurity and... (Publications)
achievement among boys (p < 0.05), whereas higher levels of cardiorespiratory fitness and not being stunted explained most variance in academic achievement in girls (p < 0.05). Higher age turned out to [...] performance in the Flanker task (p < 0.01). Additionally, in boys, higher grip strength was associated with better information processing and inhibitory control of attention (p < 0.01), whereas in girls, higher [...] higher cardiorespiratory fitness levels were positively associated with...
Validation of a human-serum-based <em>in vitro </em>growth method for drug screening on juvenile development stages of <em>Schistosoma mansoni</em> (Publications)
serum were similar in size as in vivo worms until 28 days of incubation (males 1.4 +/- 0.2 mm, females 1.1 +/- 0.5 mm long). qPCR analysis revealed similar gender distribution both on newly transformed [...] development, where a slightly lower activity was observed for the in vitro grown worms (IC50: 0.54 muM in vitro, 0.14 muM in vivo 72 hours post-incubation). The evaluation of five additional drugs revealed [...] sensitivity on in vitro developed schistosomes when compared to in vivo grown...
Validity of ambient levels of fine particles as surrogate for personal exposure to outdoor air pollution--results of the European EXPOLIS-EAS Study... (Publications)
contrast, the associations were weaker for traffic (Pb: n = 44, rSp = 0.53; Br: n = 44, rSp = 0.21) and crustal (Ca: n = 44, rSp = 0.12) indicators. This contrast is consistent with spatially homogeneous [...] rSpearman (Sp) = 0.07). In the group reporting neither relevant indoor sources nor relevant activities, personal exposures and home outdoor levels of sulfur were highly correlated (n = 40, rSp = 0.85). In contrast
Role of immune cells in animal models for inherited neuropathies: facts and visions (Publications)
Mice heterozygously deficient in the peripheral myelin adhesion molecule P0 (P0+/- mice) are models for some forms of Charcot-Marie-Tooth (CMT) neuropathies. In addition to the characteristic hallmarks [...] revealed macrophages in close apposition to myelin and demyelinated axons. We therefore cross-bred the P0+/- mice with spontaneous osteopetrotic (op) mutants deficient in the macrophage colony-stimulating factor [...] elevated in the peripheral nerves, and the demyelinating phenotype was...
Rosetting in <em>Plasmodium vivax</em>: a cytoadhesion phenotype associated with anaemia (Publications)
among anaemic individuals compared to non-anaemic (p = 0.010) and decreased with increasing haematocrit (p = 0.033) and haemoglobin levels (p = 0.015). CONCLUSIONSSIGNIFICANCE: P. vivax peripheral isolates [...] haplotype was more frequently found among pregnant women (33%) than in non-pregnant women (0%) and men (4%; p = 0.010). Rosetting was observed in 64% of the isolates, adhesion to CSA in 15%, to ICAM1 in
