Influences of animal-assisted therapy on episodic memory in patients with acquired brain injuries (Publications)
positive compared to standard therapy sessions without animals (Z = -3.21, p = 0.002, g = 0.70; Z = -2.75, p = 0.006, g = 0.96). Qualitative data analysis resulted in a total of 23 categories. The most
Physical activity is inversely associated with multimorbidity in elderly men: results from the KORA-Age Augsburg Study (Publications)
(OR) for multimorbidity was 0.73 (95% CI: 0.60-0.90) for a 1 standard deviation increase of the PASE score. No significant results could be observed for women (OR: 1.05; 95% CI: 0.83-1.33). CONCLUSION: We
Insulin-like growth factor-1 promoter polymorphisms and colorectal cancer: a functional genomics approach (Publications)
conferred an approximate 40% decrease in risk in comparison to genotype CC (odds ratio, 0.59; 95% confidence interval, 0.45 to 0.77). This association was stronger for colon cancer than for rectal cancer (p(h [...] within the Singapore Chinese Health Study. RESULTS: We identified a common (minor allele frequency = 0.36) single-nucleotide polymorphism (SNP), IGF1-2995 C/A, within a consensus domain for an octamer binding
3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential (Publications)
15, was equipotent across the two strains (K1 = 25.0 nM, NF54 = 28.0 nM) and superior to chloroquine in the K1 strain (chloroquine IC(50) K1 = 194.0 nM). Compound 15 completely cured Plasmodium berghe [...] mice with a single oral dose of 30 mg/kg. Dose-response studies generated ED(50) and ED(90) values of 0.83 and 1.74 mg/kg for 15 in the standard four-dose Peters test. Pharmacokinetic studies in the rat indicated
Inflammatory response and IgE sensitization at early age (Publications)
increased CRP levels at the age of 1 yr (level in the highest vs. lowest quartile: aOR 0.48, 95% CI 0.24-0.95; p = 0.014). The risk of AD and asthma was not significantly related to CRP. CONCLUSION: The
Methods matter: a comparative review of health risk assessments for ambient air pollution in Switzerland (Publications)
oscillated from 0.40 to 2.09 (times the STE-2010 value). Regarding input data, the ratio ranged from 0.69 to 1.26 for population exposure, from 0 to 1.81 for counterfactual scenario, from 0.96 to 1.13 for
The association of road traffic noise with problem behaviour in adolescents: a cohort study (Publications)
analyses. In cross-sectional analyses, peer relationship problems increased by 0.15 units (95%CI: 0.02, 0.27; scale range: 0-10) per 10dB road traffic noise increase. In longitudinal analyses, increases
Evolution of COVID-19 mortality over time: results from the Swiss hospital surveillance system (CH-SUR) (Publications)
COVID-19 (13.0%). We found that overall in-hospital mortality was lower during the second wave of COVID-19 than in the first wave (hazard ratio [HR] 0.70, 95% confidence interval [CI] 0.63- 0.78; p
Influences of animal-assisted therapy on episodic memory in patients with acquired brain injuries (Publications)
positive compared to standard therapy sessions without animals (Z = -3.21, p = 0.002, g = 0.70; Z = -2.75, p = 0.006, g = 0.96). Qualitative data analysis resulted in a total of 23 categories. The most
Physical activity is inversely associated with multimorbidity in elderly men: results from the KORA-Age Augsburg Study (Publications)
(OR) for multimorbidity was 0.73 (95% CI: 0.60-0.90) for a 1 standard deviation increase of the PASE score. No significant results could be observed for women (OR: 1.05; 95% CI: 0.83-1.33). CONCLUSION: We
