The low and declining risk of malaria in travellers to Latin America: is there still an indication for chemoprophylaxis? (Publications)
transmission and malaria imported by travellers to identify the utility of national and regional annual parasite index (API) in predicting malaria risk and its value in generating recommendations on malaria [...] America and imported into the USA and nine European countries. Between 2000 and 2004, most countries reported declining malaria transmission. Highest API's in 2003/4 were in Surinam (287.4) Guyana (209.2) and
Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of <em>Plasmodium falciparum</em> enoyl-ACP-reductase... (Publications)
Malaria, a disease of worldwide significance, is responsible for over one million deaths annually. The liver-stage of Plasmodium's life cycle is the first, obligatory, but clinically silent step in malaria [...] prophylaxis and liver-stage eradication. In this paper, new coumarin-based triclosan analogues are reported and their biological profile is explored in terms of inhibitory potency against enzymes of the PfFAS-II
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
transmission. Early studies reported a temporal association between ACT introduction and reduced malaria transmission in a number of ecological settings. However, these reports have come from areas with [...] may have reduced malaria transmission, and have not included a comparison group without ACT. This report presents results from the first large-scale observational study to assess the impact of case management [...] in 2001, 2002, 2004, 2005 and 2006. FINDINGS: Among 37,309 observations...
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
transmission. Early studies reported a temporal association between ACT introduction and reduced malaria transmission in a number of ecological settings. However, these reports have come from areas with [...] may have reduced malaria transmission, and have not included a comparison group without ACT. This report presents results from the first large-scale observational study to assess the impact of case management [...] in 2001, 2002, 2004, 2005 and 2006. FINDINGS: Among 37,309 observations...
Stratification of malaria incidence in Papua New Guinea (2011–2019): contribution towards a sub-national control policy (Publications)
of 808 health facilities were delineated using a travel-time accessibility approach and linked to reported malaria cases (2011–2019). Zonal statistics tools were used to calculate average altitude and air [...] empirical Bayesian kriging (EBK) was employed to interpolate incidence risk strata across PNG. Malaria annual incidence rates are, on average, 186.3 per 1000 population in catchment areas up to 600 m, dropped [...] above 1400 m altitude. In areas above the two altitudinal thresholds 600m...
The cost of urinary incontinence in Italian women: a cross-sectional study (Publications)
ated random number lists. RESULTS: A total of 2767 women were identified. Of these, 408 (14.7%) reported UI during the year before the interview and 229 underwent a detailed interview on UI-related costs [...] tests). The only appreciable treatment cost, according to the INHS perspective, was for diapers. The annual cost per patient for diapers was L255,519. The prevalence of UI in women aged > 40 years in Italy [...] is estimated in the study at 9.3%. Thus, combining this information with the...
Stratification of malaria incidence in Papua New Guinea (2011–2019): contribution towards a sub-national control policy (Publications)
of 808 health facilities were delineated using a travel-time accessibility approach and linked to reported malaria cases (2011–2019). Zonal statistics tools were used to calculate average altitude and air [...] empirical Bayesian kriging (EBK) was employed to interpolate incidence risk strata across PNG. Malaria annual incidence rates are, on average, 186.3 per 1000 population in catchment areas up to 600 m, dropped [...] above 1400 m altitude. In areas above the two altitudinal thresholds 600m...
The cost of urinary incontinence in Italian women: a cross-sectional study (Publications)
ated random number lists. RESULTS: A total of 2767 women were identified. Of these, 408 (14.7%) reported UI during the year before the interview and 229 underwent a detailed interview on UI-related costs [...] tests). The only appreciable treatment cost, according to the INHS perspective, was for diapers. The annual cost per patient for diapers was L255,519. The prevalence of UI in women aged > 40 years in Italy [...] is estimated in the study at 9.3%. Thus, combining this information with the...
Randomised trial of SPf66 vaccine against <em>Plasmodium falciparum</em> malaria in children in southern Tanzania (Publications)
children. Under conditions of a field experiment, the annual incidence of a febrile illness (axillary temperature > or = 37.5 degrees C) reported to the curative primary health services in each child was
Randomised trial of SPf66 vaccine against <em>Plasmodium falciparum</em> malaria in children in southern Tanzania (Publications)
children. Under conditions of a field experiment, the annual incidence of a febrile illness (axillary temperature > or = 37.5 degrees C) reported to the curative primary health services in each child was
