Long-term exposure to air pollution and chronic kidney disease-associated mortality - results from the pooled cohort of the European multicentre... (Publications)
1.31 (1.03-1.66) per 5μg/m(3), BC (1.26 (1.03-1.53) per 0.5×10(- 5)/m), NO(2) (1.13 (0.93-1.38) per 10μg/m(3)) and inverse for O(3) (0.71 (0.54-0.93) per 10μg/m(3)). Results were robust to further covariate
Outdoor air pollution and hormone-assessed pubertal development in children: results from the GINIplus and LISA birth cohorts (Publications)
microg/m(3) increase in ozone concentration, odds ratios and 95% confidence intervals were 0.900 (0.605, 1.339) and 0.830 (0.573, 1.203) for females and males, respectively. Stratified by area, the aforementioned [...] development was assessed by dichotomizing the concentration of hormones in serum at 18.4 pmol/L and 0.087 nmol/L using the lower limits of quantification for estradiol and testosterone, respectively. Land-use
Reduced fertility associated with HIV: the contribution of pre-existing subfertility (Publications)
Pre-existing low gravidity was strongly associated with a reduced incidence of pregnancy (odds ratio 0.39; CI 0.19-0.81). Additionally, adjusting for low gravidity reduced the estimate of the effect of HIV infection [...] 83 women beginning in the 3 months following 47 (7.0%) of 669 visits made by HIV-infected women and 77 (9.5%) of 812 visits by HIV-negative women (P = 0.12). Adjusting for age, lactation, illness, STD and
Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas (Publications)
gemistocytic astrocytoma was poor, with survival rates of 16% at 5 years and 0% at 10 years. Younger patients ( 50 years; P=0.013). DNA sequencing, performed in 84% of cases, revealed that TP53 mutations [...] low-grade diffuse gliomas (log-rank test; P=0.047), but when each histological type was analyzed separately, an association was observed only for oligoastrocytoma ( P=0.05). Loss on 1p and 19q were assessed [...] Standard Population, per million population per year, were 2.28 for low-grade...
Deltamethrin-impregnated bednets reduce human landing rates of sandfly vector <em>Lutzomyia longipalpis</em> in Amazon households (Publications)
room by 56% (95% CI 52-59%), and increased 24-h mortality to 68% (95% CI 62-73%) compared to 0.4% (0.1-2.0%) in untreated houses. The reduction in human landing rates in ITN rooms was associated with a [...] 34-44%), reduced human landing rates by 80% (95% CI 62-90%) and increased the 24-h mortality rate from 0% to 98% (95% CI 93-99%) inside ITNs. The presence of an ITN also reduced the human landing rate on [...] owned at least one net (median two, range 1-8), only 20% of the population slept...
Source apportionment of population representative samples of PM2.5 in three European cities using structural equation modelling (Publications)
of the variability of elemental (R(2)> 0.6 except for Ca in Basle 0.38) and chemical concentrations (R(2)> 0.5 except benzene in Basle 0.22 and nonane in Athens 0.39) are explained by the source factors
Socially marketed insecticide-treated nets improve malaria and anaemia in pregnancy in southern Tanzania (Publications)
users (625 parasites/microl vs. 1173 parasited/microl: P=0.01). Fewer ITN users were anaemic (Hb < 11 g/dl) than ITN non-users (72 vs. 82%: P=0.01). ITNs had a PE of 12% (CI 2-21) against mild anaemia [...] anaemia was 68% compared with 82% for those without nets (P=0.002); prevalence of malaria was 22% compared with 33% for those without nets (P=0.02). Knowledge and reported use of the discount voucher system [...] had the lowest ITN use. Fewer ITN users were positive for malaria than ITN...
Randomized, double-blind, placebo-controlled trial of oral artemether for the prevention of patent <em>Schistosoma haematobium </em>infections (Publications)
efficacy: 0.25, 95% CI: 0.08-0.38, P = 0.007). The geometric mean infection intensity in the artemether group was less than half that of the placebo recipients (3.4 versus 7.4 eggs/10 mL urine, P < 0.001).
The antiprotozoal activity of sixteen asteraceae species native to Sudan and bioactivity-guided isolation of xanthanolides from <em>Xanthium... (Publications)
from this extract, 8-epixanthatin 1beta,5beta-epoxide showed IC (50) values of 0.09, 2.95, 0.16 and 1.71 microg/mL (0.33, 11.3, 0.6 and 6.5 microM) against T. BRUCEI RHODESIENSE, T. CRUZI, L. DONOVANI and [...] TRYPANOSOMA BRUCEI RHODESIENSE, the etiological agent of East African human trypanosomiasis (IC (50) = 0.1 microg/mL). This plant extract also exhibited noticeable activities against T. CRUZI (Chagas disease)
Oral artemether for prevention of <em>Schistosoma mansoni</em> infection: randomised controlled trial (Publications)
risk: 0.50 [95% CI 0.35-0.71], p=0.00006). The geometric mean egg output among positive children in the artemether group was significantly lower than in placebo recipients (19 vs 32 eggs/g stool, p=0.017)
