A multinational case-control study on childhood brain tumours, anthropogenic factors, birth characteristics and prenatal exposures: a validation of... (Publications)
Agreement between interview and birth registry data ranged from moderate (Kappa=0.54; worked during pregnancy) to almost perfect (Kappa=0.98; birth weight). Neither anthropogenic factors nor birth characteristics [...] tumour risk. Maternal vitamin intake during pregnancy was indicative of a protective effect (OR 0.75, 95%-CI: 0.56-1.01). No association was seen for maternal smoking during pregnancy or working during pregnancy
Associations between lung function and estimated average exposure to NO2 in eight areas of Switzerland (Publications)
the same community was associated with a change in average FVC by -0.59% [95% confidence limits (CL) = 0.01, -1.19] and -0.74% (95% CL = -0.07, -1.41), respectively. These values, however, are smaller than
Socioeconomic status and childhood leukemia incidence in Switzerland (Publications)
the highest with the lowest SES category ranged from 0.95 (95% CI: 0.71-1.26; P trend?=?0.73) for paternal education to 1.37 (1.00-1.89; P trend?=?0.064) for maternal education. No effect modification was
Passive smoking exposure among adults and the dynamics of respiratory symptoms in a prospective multicenter cohort study (Publications)
outcomes considered, showing HR values from 1.09 to 1.21 for developing symptoms and HR values from 0.91 to 0.83 for getting rid of them. Exposure to environmental tobacco smoke, including the workplace, was [...] with the length of episodes of any respiratory symptom and lower-respiratory-tract symptoms (HR 0.78-0.77). CONCLUSIONS: The results suggest that exposure to environmental tobacco smoke has adverse effects
Associations of novel and traditional vascular biomarkers of arterial stiffness: results of the SAPALDIA 3 cohort study (Publications)
forward and backward wave were significant predictors of cIMT (p < 0.001). All parameters were significantly associated with LD (p < 0.001), with aPWV and the amplitude of the forward wave explaining the [...] proportion of variance (2%). Only CAVI and baPWV were significant predictors of DC (p < 0.001), explaining more than 0.3% of the DC variance. CONCLUSION: We demonstrated that novel non-invasive oscillometric
Microbiological risk infection assessment using QMRA in agriculture systems in Côte d'Ivoire, West Africa (Publications)
is estimated at 0.01 per person per year (pppy) for Giardia lamblia and 0.2 pppy for Escherichia coli O157:H7. The annual risk from salad consumption is 0.01 pppy for G. lamblia and 0.9 pppy for E. coli
Development and evaluation of a multiplex quantitative real-time polymerase chain reaction for hookworm species in human stool (Publications)
multiplex qPCR showed very good agreement for the detection of both N. americanus (Kappa 0.943) and Ancylostoma spp. (Kappa 0.936) with a multiplex STH qPCR. A strong and moderate quantitative correlation between [...] was obtained for the hookworm qPCR for seeded DNA egg extracts (R(2) > /= 0.9004) and naturally egg-infected individuals (R(2) = 0.6848), respectively. The newly developed hookworm quantitative multiplex
Demand-side financing in the form of baby packages in Northern Mozambique: results from an observational study (Publications)
began). The non-intervention districts showed a slight increase, from a mean IBR of 0.39 (SD = 0.10) in 2006 to 0.67 (SD = 0.13) in 2014. The intervention district had a dramatic increase in IBRs within six
A cluster randomized trial assessing the effect of a digital health algorithm on quality of care in Tanzania (DYNAMIC study) (Publications)
was 37.3% in intervention facilities, and 76.4% in control facilities (adjusted risk ratio 0.5; 95% CI 0.4 to 0.7; p [...] assessed in intervention health facilities was 46.4% (range 7.7% to 91.7%) compared to 26.3% (range 0% to 66.7%) in control health facilities, an adjusted difference of 15.1% (95% confidence interval [CI]
Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box (Publications)
activity against adult S. mansoni was observed with MMV1581558 (EC50 value of 0.18 +/- 0.01 microM) and nitazoxanide (0.47 +/- 0.07 microM). Of the five compounds tested in vivo, MMV1581558 and the approved