Comparison of nasal microbiota between preterm and full-term infants in early life (Publications)
infants exhibited a distinct composition compared to that of full-term infants (PERMANOVA, R(2) = 0.014, p = 0.001), characterized by a reduced abundance of the Moraxella and Dolosigranulum genera (ANCOM-BC [...] RESULTS: Presence of older siblings in preterm infants was associated with β-diversity (PERMANOVA p = 0.001) and an increased abundance of Moraxella and Haemophilus. The nasal microbiota of preterm infants
Maternal HIV and drug use: effect on health and social morbidity (Publications)
maternal drug use exerting a negative influence on outpatient visits (odds ratio 0.6, 95% confidence interval 0.4 to 1.0). At 6 weeks, the majority of children lived with their birth parent(s), and no
HIV infection disrupts the sympatric host-pathogen relationship in human tuberculosis (Publications)
interval [95% CI] 1.21-infinity, p = 0.03). HIV infection was significantly associated with TB caused by an allopatric (as opposed to sympatric) M. tuberculosis lineage (OR 7.0, 95% CI 2.5-19.1, p [...] 2008 in Switzerland. We analyzed 518 TB patients of whom 112 (21.6%) were HIV-infected and 233 (45.0%) were born in Europe. We found that among European-born TB patients, recent transmission was more likely
<em>In vitro</em> metabolic profile and <em>in vivo</em> antischistosomal activity studies of (n6-praziquantel)Cr(Co)3 derivatives (Publications)
activity was observed. The R-enantiomers are highly active against adult schistosomes in vitro (IC50 0.08-0.13 ?M), whereas both S-enantiomers lack activity. The in vivo activity of 1 and 2 was then studied [...] infection. A single dose of 1 and 2 (400 mg/kg) resulted in low worm burden reductions of 24% and 29% (p > 0.05).
Eleganolone, a Diterpene from the French marine alga <em>Bifurcaria bifurcata</em> inhibits growth of the human pathogens <em>Trypanosoma brucei</em>... (Publications)
contributes only mildly to the trypanocidal activity of the ethyl acetate extract (IC(50) = 45.0 microM, SI = 4.0). However, a selective activity against P. falciparum erythrocytic stages in vitro has been [...] Bifurcaria bifurcata, showed strong trypanocidal activity with a mild selectivity index (IC(50) = 0.53 microg/mL; selectivity index (SI) = 11.6). Bio-guided fractionation led to the isolation of eleganolone
Effects of a school-based physical activity program on physical and psychosocial quality of life in elementary school children: a cluster-randomized... (Publications)
size [d], 0.32; p < .05). Subpopulation analyses revealed that this effect was caused by an effect in urban (effect size [d], 0.38; p < .05) and overweight first graders (effect size [d], 0.45; p < .05)
Effect of ambient air pollution on hospital admission for respiratory diseases in Hanoi children during 2007-2019 (Publications)
at lag 0. A 10 μg/m(3) increase in the concentration of PM(10), PM(2.5), PM(1), SO(2), NO(2), O(3) 8-h maximum and 1000 μg/m(3) increase in CO concentration was associated with 0.6%, 1.2%, 1.4%, 0.8%, 1 [...] 1.6%, 0.3%, and 1.7% increase in odd of admission for all respiratory diseases among children under 16 years at lag 0-2. All PM metrics and NO(2) are associated with childhood admission for pneumonia and
Sub-lethal aquatic doses of pyriproxyfen may increase pyrethroid resistance in malaria mosquitoes (Publications)
exposures were tested using WHO-standard susceptibility assays on pyrethroids (0.75% permethrin and 0.05% deltamethrin), carbamates (0.1% bendiocarb) and organochlorides (4% DDT). Biochemical basis of pyrethroid [...] pre-exposure to 4% PBO. Bio-efficacies of long-lasting insecticide-treated nets, Olyset(R) and PermaNet 2.0 were also examined against adult mosquitoes with or without previous aquatic exposure to PPF. RESULTS: [...] but not to bendiocarb or DDT. Mortality rates after exposure to...
Health impact assessment of waste management facilities in three European countries (Publications)
and England, respectively. The additional contribution to NO2 levels within a 3 km radius was 0.23, 0.15, and 0.14 mug/m3, respectively. Lower values were found for PM10. Assuming that the incinerators continue [...] that the annual number of cancer cases due to exposure in 2001-2020 will reach 11, 0, and 7 in 2020 and then decline to 0 in the three countries in 2050. We are moderately confident that by 2050, the at
Evaluation of customised lineage-specific sets of MIRU-VNTR loci for genotyping <em>Mycobacterium tuberculosis</em> complex isolates in Ghana (Publications)
isolates (clustering rate: 0.9%) and 104 singletons. Among, 52 Lineage 5 isolates, customized MIRU-12 genotyping defined 51 patterns with 1 cluster of 2 isolates (clustering rate: 0.9%) and 50 unique strains [...] Cumulative HGDI values for customized MIRU-12 for Lineages 4 and 5 were 0.98 respectively whilst that of standard MIRU-15 was 0.99. A union of loci from the customised MIRU-12 and standard MIRU-15 revealed [...] eight highly discriminatory loci: 4052, 2163B, 40, 4165, 2165, 10,16 and...
