<em>Plasmodium falciparum </em>malaria disease manifestations in humans and transmission to<em> Anopheles gambiae</em>: a field study in Western Kenya (Publications)
(P = 0.05) than healthy volunteers. Ookinete development occurred in only 6 out of the 21 symptomatic patients, of which only 33.3% successfully yielded oocysts. The oocyst prevalence was only 0.6% in [...] 546 mosquitoes that were fed on blood from this symptomatic group, with mean oocyst intensity of 0.2 (range 0-2) oocysts per mosquito. In contrast, a higher proportion (76.7%) of healthy gametocyte carriers
Indoors man-biting mosquitoes and their implication on malaria transmission in Mpwapwa and Iringa Districts, Tanzania (Publications)
Anopheles gambiae s.l., 0.2% (N = 3) were An. funestus, and 20.3% (N = 262) were Culex quinquefasciatus. Other species including Cx cinereus, An. coustani and Aedes spp accounted for 0.5% of the mosquito [...] respectively. Indoor pyrethrum spray catch gave an overall estimate of An. gambiae density of 8 and 0.6 mosquitoes per room in Iringa and Mpwapwa, respectively, whereas light trap collections gave an overall [...] 9 and 2.9 mosquitoes per room. The densities of house entering mosquitoes...
Severe malaria and concomitant bacteraemia in children admitted to a rural Mozambican hospital (Publications)
was also present (from 4.0% to 22.0%, P < 0.0001), and bacteraemia was an independent risk factor for death among severe malaria patients (adjusted OR 6.2, 95% CI 2.8-13.7, P = 0.0001). Streptococcus pneumoniae
Adult cancers near high-voltage overhead power lines (Publications)
to the power lines (0-49 m) compared with distances 600-1000 m, odds ratios (ORs) ranged from 0.82 (95% confidence interval = 0.61-1.11; 66 cases) for malignant melanoma to 1.22 (0.88-1.69) for brain/central
Microsatellite and mitochondrial genetic differentiation of <em>Anopheles arabiensis</em> (Diptera: Culicidae) from western Kenya, the Great Rift... (Publications)
level of genetic differentiation (F(ST) = 0.116) four to seven times higher than markers outside inversions (F(ST) = 0.016) or inside fixed inversions (F(ST) = 0.027). Mitochondrial ND5 gene sequences did [...] did not reveal significant genetic differentiation for the same four populations (phi(ST) = -0.008). The contrasts in the level of genetic differentiation between microsatellite markers inside polymorphic
Statistical modeling of the spatial variability of environmental noise levels in Montreal, Canada, using noise measurements and land use... (Publications)
using continuous 2-min noise measurements from 204 sites. Model performance (adjusted R2) was 0.68, 0.59, and 0.69 for LAeq24h, Lnight, and Lden, respectively. Main predictors of measured noise levels were [...] measurements corresponded well with LAeq24h levels computed over 5 days at road-traffic sites (bias: -0.7 dB(A)), but not at rail (-2.1 dB(A)) nor at air (-2.2 dB(A)) sites. Our study provides important insights
Association between advanced glycation end products and impaired fasting glucose: results from the SALIA study (Publications)
groups (all p> 0.05). Associations between plasma levels of AGEs and fasting glucose, insulin and HOMA-IR as a measure of insulin resistance were weak (r between -0.2 and 0.2, all p> 0.05). The association
Treatment of breast cancer in the elderly: a prospective, population-based Swiss study (Publications)
(BCS) in stages I–II BC (0.37), sentinel lymph node dissection (SLND) in patients with no palpable adenopathy (0.58), post-BCS radiotherapy (0.04) and adjuvant endocrine treatment (0.23) were all in disfavor
Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
a Phenomenex C8(2) analytical column (50.0mmx2.0mm, 5mum) with a mobile phase of acetonitrile (buffer B) and 5mM ammonium formate (buffer A) at a flow-rate of 0.3mL/min and a gradient from 20% to 95% a [...] was between 156.25ng/mL and 5mug/mL and the achieved correlation coefficient (r(2)) was greater than 0.99. The validation results demonstrated that the developed LC/MS method is precise, accurate, and selective
Association of early-life exposure to household gas appliances and indoor nitrogen dioxide with cognition and attention behavior in preschoolers (Publications)
Nitrogen dioxide concentrations were associated with cognitive function (a decrease of 0.27 point per 1 ppb, 95% CI: -0.48, -0.07) and inattention symptoms (odds ratio = 1.06, 95% CI: 1.01, 1.12). The deleterious [...] cognitive outcomes (beta coefficient for general cognition = -5.10, 95% confidence interval (CI): -9.92, -0.28; odds ratio for inattention symptoms = 3.59, 95% CI: 1.14, 11.33), independent of social class and
