Insecticide-treated eave nets and window screens for malaria control in Chalinze district, Tanzania: a study protocol for a household randomised... (Publications)
Long-lasting insecticidal nets (LLINs) have contributed to the reduction of malaria in sub-Saharan Africa, including Tanzania. However, they rely on daily user behaviour and high coverage which is difficult [...] reduced efficacy of control tools. To overcome these problems, we propose to evaluate a new tool for house modification, the insecticide-treated eave nets (ITENs) in combination with insecticide-treated window
The development of an ivermectin-based attractive toxic sugar bait (ATSB) to target <em>Anopheles arabiensis</em> (Publications)
BACKGROUND: An increasing number of countries in sub-Saharan Africa are moving towards malaria-elimination, mostly thanks to successful vector control campaigns. However, elimination has proven challenging [...] arabiensis to sugar feed. The optimized prototype was then placed in different locations within a screen-house, colour-coded with different food dyes, containing competing vegetation (Ricinus communis) and ex
falciparum , the deadliest of the five malaria pathogens and the most common in Africa. Swiss TPH has played a leading role in this day coming to fruition thanks to decades of research and development [...] S/AS01, debuting a tool that could save the lives of tens of thousands of children in sub-Saharan Africa each year. The vaccine is not just a first for malaria — it is the first developed for any parasitic [...] malaria eradication. Malaria remains a primary cause of childhood illness and...
Herzinsuffizienz in Afrika? (Publications)
Heart Failure in Africa Abstract. In Africa, mortality due to heart failure is twice as high as in other low- to middle-income countries and five times as high as in high-income countries. Arterial hy [...] well-controlled hypertension. The neglect of chronic non-communicable diseases on the health agenda leads to poor awareness, poor diagnostic resources, preventions strategies and treatment options. International
Herzinsuffizienz in Afrika? (Publications)
Heart Failure in Africa Abstract. In Africa, mortality due to heart failure is twice as high as in other low- to middle-income countries and five times as high as in high-income countries. Arterial hy [...] well-controlled hypertension. The neglect of chronic non-communicable diseases on the health agenda leads to poor awareness, poor diagnostic resources, preventions strategies and treatment options. International
of medications is also a challenge, as they are often sold in markets without expert advice. This leads, for example, to active ingredients not being dosed correctly and therewith ineffective treatment [...] the Swiss Centre for International Health, where, in addition to her research projects, she also leads international consultancy mandates on clean drinking water and hygiene (WASH), NTDs, One Health and [...] drive research forward. For example, she would like to promote more international...
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate... (Publications)
areas of high transmission in Africa. We describe a structure-based computationally driven lead optimization program of a pyrrole-based series of DHODH inhibitors, leading to the discovery of two candidates
Potent antimalarials with development potential identified by structure-guided computational optimization of a pyrrole-based dihydroorotate... (Publications)
areas of high transmission in Africa. We describe a structure-based computationally driven lead optimization program of a pyrrole-based series of DHODH inhibitors, leading to the discovery of two candidates
Analyzing the contributions of transdisciplinary research to the global sustainability agenda in African cities (Publications)
Coast), Abuja Metro (Nigeria), Mbour (Senegal), Cape Town (South Africa), Nelson Mandela Bay Metro (South Africa), Grahamstown (South Africa) and Kampala (Uganda) and data were collected on each of the five [...] (ii) processes and (iii) products. The five projects were funded under the Leading Integrated Research for Agenda 2030 in Africa (LIRA) programme. The projects were being implemented in nine cities across [...] the contributions of the five TDR projects toward the achievements of the...
African fermented dairy products – overview of predominant technologically important microorganisms focusing on African <em>Streptococcus infantarius... (Publications)
especially when raw milk is consumed. In Africa, poor processing and storage conditions contribute to contamination, outgrowth and transmission of pathogens, which lead to spoilage, reduced food safety and [...] safety. Traditionally-fermented sour milk products are culturally accepted and widely distributed in Africa, and rely on product-specific microbiota responsible for aroma, flavor and texture. Knowledge of [...] with enhanced quality and safety, as well as sustainable interventions for...
