Treatment of breast cancer in the elderly: a prospective, population-based Swiss study (Publications)
(BCS) in stages I–II BC (0.37), sentinel lymph node dissection (SLND) in patients with no palpable adenopathy (0.58), post-BCS radiotherapy (0.04) and adjuvant endocrine treatment (0.23) were all in disfavor
Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate (Publications)
a Phenomenex C8(2) analytical column (50.0mmx2.0mm, 5mum) with a mobile phase of acetonitrile (buffer B) and 5mM ammonium formate (buffer A) at a flow-rate of 0.3mL/min and a gradient from 20% to 95% a [...] was between 156.25ng/mL and 5mug/mL and the achieved correlation coefficient (r(2)) was greater than 0.99. The validation results demonstrated that the developed LC/MS method is precise, accurate, and selective
Association of early-life exposure to household gas appliances and indoor nitrogen dioxide with cognition and attention behavior in preschoolers (Publications)
Nitrogen dioxide concentrations were associated with cognitive function (a decrease of 0.27 point per 1 ppb, 95% CI: -0.48, -0.07) and inattention symptoms (odds ratio = 1.06, 95% CI: 1.01, 1.12). The deleterious [...] cognitive outcomes (beta coefficient for general cognition = -5.10, 95% confidence interval (CI): -9.92, -0.28; odds ratio for inattention symptoms = 3.59, 95% CI: 1.14, 11.33), independent of social class and
Dynamics of people's socio-economic status in the face of schistosomiasis control interventions in Ukerewe district, Tanzania (Publications)
This decrease/increase was significant. The median shifted from -0.761 to -0.448, and the mean from -0.204 (standard deviation (SD) 1.924) to 0.193 (SD 2.079) between pre- and post-intervention phases. The
Alcohol consumption and other lifestyle factors: avoidable sources of excess lead exposure (Publications)
drinking habits. The age-adjusted geometrical mean blood lead level was 0.38 +/- 0.19 mumol/litre of whole blood for males, and 0.29 +/- 0.17 mumol/litre for females. The average lead burden was about 30% below
Perceived ill-health and health seeking behavior in two communities in the nam theun 2 hydroelectric project area in Lao People's Democratic... (Publications)
least primary schooling (49.2% versus 17.5%, P < 0.01). Self-medication with antimalarials was more common in Xe Bang Fai than on Nakai (32.3% versus 7.0%, P < 0.001). The mean amount of money spent per health [...] period: 2 weeks) went to a local health volunteer compared to only 7.2% in the Xe Bang Fai area (P < 0.001). In Nakai, there were disproportionately more illiterates seeking help from local health volunteers
Associations between infections and clinical outcome parameters in status epilepticus: a retrospective 5-year cohort study (Publications)
during SE had longer SE duration (p < 0.0001), longer ICU stay (p = 0.0041), higher risk of RSE (odds ratio [OR] 4.8, p = 0.0002), and higher mortality (OR 5.2, p = 0.0003) than those without infectious
Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II (Publications)
occupational asthmagens (OR (95% CI) 1.6 (1.0-2.40) and 1.7 (1.2-2.5), respectively); high (1.7 (1.0-2.8) and 1.9 (1.3-2.9), respectively) and low (1.6 (1.0-2.7) and 1.8 (1.2-2.7), respectively) molecular [...] molecular weight agents; and cleaning agents (2.0 (1.1-3.6) and 2.3 (1.4-3.6), respectively), with stronger associations for long-term exposures. These associations were mainly explained by the exacerbation
Convergent methods assessing bone growth in an experimental model at dental implants in the minipig (Publications)
l method of measurement showed high level of concordance (concordance coefficient=0.912 and correlation coefficient=0.939) for fBIC. Similar results were observed for vertical new bone and for remnants [...] Discrepancies for new bone and for mineralized tissue resulted in concordance coefficient of 0.182 and 0.054. The results indicate that contact X-rays can be used for morphometric assessments regarding
Atopic conditions and brain tumor risk in children and adolescents: an international case-control study (CEFALO) (Publications)
ratio 1.03; 95% confidence interval (CI) 0.70-1.34]. The OR was 0.76 (95% CI 0.53-1.11) for a current atopic condition (in the year before diagnosis) and 1.22 (95% CI 0.86-1.74) for an atopic condition in the
