Efficacy and safety of moxidectin, synriam, synriam-praziquantel <em>versus</em> praziquantel against <em>Schistosoma haematobium</em> and <em>S.... (Publications)
praziquantel and praziquantel yielded CRs of 60.0% and 38.5% and ERRs of 96.0% and 93.5%, respectively. CRs observed in the treatment of S. mansoni were 13.0%, 6.7%, 27.0%, and 27.6% for moxidectin, Synriam, Synriam
Improving household air, drinking water and hygiene in rural Peru: a community-randomized-controlled trial of an integrated environmental home-based... (Publications)
control arm. This corresponds to a relative rate of 0.78 [95% confidence interval (CI): 0.58-1.05] for diarrhoea incidence and an odds ratio of 0.71 (95% CI: 0.47-1.06) for diarrhoea prevalence. No effects on
Long-term physical activity is associated with reduced arterial stiffness in older adults: longitudinal results of the SAPALDIA cohort study (Publications)
with sufficient moderate-to-vigorous PA (i) in SAPALDIA 2 but not in SAPALDIA 3 (P = 0.048) and (ii) in both surveys (P = 0.001) compared with persons with insufficient activity in both surveys. There was [...] baPWV (P = 0.03). The triples of parameter estimates describing the association between level of PA change and baPWV were not significantly different between the two sex-specific models (P = 0.07). CONCLUSIONS:
Exposure to elemental composition of outdoor PM2.5 at birth and cognitive and psychomotor function in childhood in four European birth cohorts (Publications)
-2.45 to -0.06] per 100ng/m3 increase of iron). Association between the motorized traffic component, derived from principal component analysis, and fine motor function was not significant (-0.29 points [...] points [95% CI -0.64 to 0.06] per unit increase). None of the elements were associated with gross motor function or cognitive function, although the latter estimates were predominantly negative. CONCLUSION:
Exposure to night-time traffic noise, melatonin-regulating gene variants and change in glycemia in adults (Publications)
was associated with a 0.02% (0.003-0.04%) increase in mean DeltaHbA1c in 2142 non-movers. RTN-DeltaHbA1c association was modified by MGRS among diabetic participants (Pinteraction = 0.001). A similar trend
The impact of acute air pollution fluctuations on bronchiectasis pulmonary exacerbation: a case-crossover analysis (Publications)
by 4.5% (95%CI:0.9-8.3) and 3.2% (95%CI:0.7-5.8) respectively. The overall increase in risk of exacerbation for a 10 mug/m(3) increase in air pollutant concentration was 11.2% (95%CI:6.0-16.8) for PM10 [...] PM10 and 4.7% (95%CI:0.1-9.5) for NO2 Subanalysis showed significant higher relative risks during spring (PM10 1.198, 95%CI 1.102-1.303;NO2 1.146, 95%CI:1.035-1.268) and summer (PM10 2.142, 95%CI:1.785-2.570;NO2
Data integration for the assessment of population exposure to ambient air pollution for global burden of disease assessment (Publications)
Hierarchical Model was developed to estimate annual average fine particle (PM2.5) concentrations at 0.1 degrees x 0.1 degrees spatial resolution globally for 2010-2016. The model incorporated spatially-varying [...] compared to previous (Global Burden of Disease 2013) estimates (increased within-sample R2 from 0.64 to 0.91, reduced out-of-sample, global population-weighted Root Mean Squared Error from 23 mug/m3 to
Detection and monitoring of insecticide resistance mutations in <em>Anopheles gambiae</em>: individual vs pooled specimens (Publications)
values (Ct mutant - Ct wild type probe). Polynomial regression models showed r(2) values of > 0.99 (p < 0.05). The method was validated with populations of variable allelic frequencies, and found to be [...] pilot application in field-caught samples showed minimal differences from individual genotyping (0.36(-)4.0%). It allowed the first detection of the super-kdr mutation N1575Y in An. gambiae from Mali. Using
Single-dose tafenoquine to prevent relapse of <em>Plasmodium vivax</em> malaria (Publications)
9 to 69.0), 27.7% in the placebo group (95% CI, 19.6 to 36.6), and 69.6% in the primaquine group (95% CI, 60.2 to 77.1). The hazard ratio for the risk of recurrence was 0.30 (95% CI, 0.22 to 0.40) with
Seroprotection rates of vaccine-preventable diseases among newly arrived Eritrean asylum seekers in Switzerland: a cross-sectional study (Publications)
diphtheria (> 0.1 IU/ml), tetanus (> 0.1 IU/ml), measles (> 150 mIU/ml), rubella (only for women,> 11 IU/ml), varicella (> 50 mIU/ml), hepatitis B (HbsAg Index > 0.9, antiHBc Index > 0.9 and antiHBs >
