Clinical outcome of febrile Tanzanian children with severe malnutrition using anthropometry in comparison to clinical signs (Publications)
for the MANagement of Childhood illnesses arm (risk difference -14.9%, 95% CI -26.0%, -3.8%; risk ratio 0.11, 95% CI 0.01, 0.83). Using anthropometric measures to identify and manage febrile children with
The role of HIV asymptomatic status when starting ART on adherence and treatment outcomes and implications for test and treat: the Swiss HIV Cohort... (Publications)
ART. Asymptomatic PLHIV were at a decreased risk of viral failure (adjusted hazard ratio 0.87, 95% CI: 0.76-1.00, p=0.05) and less likely to develop resistance (14% versus 27%, p [...] Asymptomatic status was not associated with reported non-adherence during follow-up (OR 1.03, 95% CI: 0.93-1.15) while 1478 PLHIV (22%) experienced viral failure a median of 1.9 years (IQR: 1.1-4.2) after
Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine (Publications)
trioxolane were synthesized; most were potent antimalarial peroxides with IC(50)s ranging from 0.20 to 7.0 ng/mL. The oral efficacies of two of these were superior to artesunate and comparable to artemether
Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine (Publications)
trioxolane were synthesized; most were potent antimalarial peroxides with IC(50)s ranging from 0.20 to 7.0 ng/mL. The oral efficacies of two of these were superior to artesunate and comparable to artemether
Genome-wide analyses identify <em>SCN5A</em> as a susceptibility locus for premature atrial contraction frequency (Publications)
lead variant, rs7373862, located in an intron of SCN5A, was associated with an increase of 0.12 [95% CI 0.08-0.16] standard deviations of the normalized PAC frequency per risk allele. Among genetic variants
Spraying tick-infested houses with lambda-cyhalothrin reduces the incidence of tick-borne relapsing fever in children under five years old (Publications)
among the 510 children. There was a significant reduction of 0.09 in the odds ratio of infection after spraying (95% confidence interval 0.01-0.87)
Abietane-type diterpenoid amides with highly potent and selective activity against <em>Leishmania donovani</em> and <em>Trypanosoma cruzi</em> (Publications)
human macrophages with a low IC50 value of 0.06 muM. This compound was also highly effective against T. cruzi amastigotes residing in L6 cells with an IC50 value of 0.6 muM and high selectivity index of 58 [...] and acrylic acid, was found to be highly potent against these parasites, displaying an IC50 value of 0.37 muM against L. donovani axenic amastigotes and an outstanding selectivity index of 63. Moreover,
Nonirritant intradermal skin test concentrations of ciprofloxacin, clarithromycin, and rifampicin (Publications)
RESULTS: Nonirritating concentrations of the three antibiotics (ciprofloxacin ~0.0067 mg/ml, clarithromycin ~0.05 mg/ml, rifampicin ~0.002 mg/ml) could be defined for healthy volunteers. Laser Doppler flowmetry
Staubförmige Verunreinigung der Luft (Publications)
and concentrations ranged befween l0 pg.m-3 lalpine) and 33 pg.m-3 (urban). Regional ratios between thoracic particles and total suspended particles were between 0.6 and 0.75. It is assumed that interactions
Antiprotozoal steroidal saponins from the marine sponge <em>Pandaros acanthifolium</em> (Publications)
the growth of Trypanosoma brucei rhodesiense (IC(50) values 0.78 and 0.038 microM, respectively) and Leishmania donovani (IC(50)'s 1.3 and 0.051 microM, respectively)
