HIV viral load as an independent risk factor for tuberculosis in South Africa: collaborative analysis of cohort studies (Publications)
(95% confidence interval [CI] 25.3-27.0). Compared to the lowest viral load category (0-999 copies/mL), the adjusted rate ratio for TB was 1.41 (95% CI 1.15-1.75, p < 0.001) in the highest group (> 10,000 [...] We included 44,260 patients with a median follow-up time of 2.7 years (interquartile range [IQR] 1.0-5.0); 3,819 incident TB cases were recorded (8.6%). At baseline, the median age was 34 years (IQR 28-41);
Exposure to road, railway, and aircraft noise and arterial stiffness in the SAPALDIA study: annual average noise levels and temporal noise... (Publications)
exposed)=32.8 (8.0) dB; Ldenrail (44.6% exposed)=30.0 (8.1) dB; Ldenroad (99.7% exposed): 54.2 (10.6) dB; NEnight=123 (179); NEday=433 (870); IRnight=73% (27); and IRday=63.8% (40.3). We observed a 0.87% (95% [...] aircraft noise levels (Ldensource), total day- and nighttime NEtime and IRtime (percent fluctuation=0%, none or constant noise; percent fluctuation=100%, high fluctuation) at the most exposed facade using [...] (95% CI: 0.31, 1.43%) increase in baPWV per IQR of Ldenrail, which was...
Efficacy and safety of co-administered ivermectin plus albendazole for treating soil-transmitted helminths: a systematic review meta-analysis and... (Publications)
analysis. Ivermectin-albendazole was significantly associated with lower risk (RR = 0.44, 95% confidence interval (CI) = 0.31-0.62) for T. trichiura infection after treatment compared to albendazole alone. The [...] transient. Overall, the number of individuals reporting any AE was not different (RR = 1.09, 95% CI = 0.87-1.36) in co-treated and albendazole-treated patients. However, although not statistically significant [...] treated with ivermectin-albendazole compared to those treated with...
Do long-lasting insecticidal nets retain their efficacy after three years of usage in Afghanistan? Findings from a study on survivorship, physical... (Publications)
three people.. Physical integrity measurements indicated that 97.0% of the LLINs were in a serviceable condition (pHI 0-642), while 3.0% were 'too torn' (pHI > 642). Functional Net survival was 93.4% (95%CI [...] endemic Afghan provinces (Balkh, Herat, Khost, Kunduz and Nangarhar) that had received LLINs (PermaNet 2.0) three years earlier were randomly selected through cluster sampling. All household heads were interviewed [...] associated with a significant reduction in mosquito...
Long-term exposure to air pollution and mortality from dementia, psychiatric disorders, and suicide in a large pooled European cohort: ELAPSE study (Publications)
29; 95 % CI: 0.98, 1.71 per 5 microg/m(3)), and BC (HR = 1.37; 95 % CI: 1.11, 1.69 per 0.5 x 10(-5)/m) with psychiatric disorders mortality, as well as with suicide (NO2: HR = 1.13 [95 % CI: 0.92, 1.38]; [...] 38]; PM2.5: HR = 1.19 [95 % CI: 0.76, 1.87]; BC: HR = 1.08 [95 % CI: 0.87, 1.35]), and no association with dementia mortality. We did not detect any positive associations of O3 and 8 PM2.5 components with
Morbidity associated with <em>Schistosoma mansoni</em> infection in north-eastern Democratic Republic of the Congo (Publications)
06-1.37, p = 0.005) was positively and significantly associated with S. mansoni infection. Hepatomegaly (aOR 1.52, 95% CI 0.99-2.32, p = 0.053) and splenomegaly (aOR 1.12, 95% CI 0.73-1.72, p = 0.619) were
<em>Strongyloides stercoralis</em> prevalence and diagnostics in Vientiane, Lao People's Democratic Republic (Publications)
not statistically different (P = 0.184). The diagnostic sensitivity of Baermann technique, KAPC, RTD-PCR, and the combination of Baermann technique and KAPC were 60.0, 60.0, 74.3, and 77.1%, respectively [...] the lowest age group of 40 years and below (22.4%), to the medium (40.0%) and to the oldest age group of 61 year and above (72.7%)(P = 0.003). The cumulative infection prevalence of CRS was considerably higher
In vitro-in vivo studies on anti-trypanosomal potentials of Zapoteca portoricensis (Publications)
rhodesiense (T. b. rhodesiense) to be 0. 372 mg/kg, while the control drug melarsoprol was 0. 006 mg/kg. On Trypanosoma brucei brucei (T. cruzi), the IC-50 is 6.42 mg/kg against 0. 87 of the reference drug Benznidazole [...] Benznidazole. The cyctotoxicity on L-6 cells exhibited an IC-50 of 0. 039 6 mg/kg against the reference drug, podophyllotoxin of 0.01 mg/kg. However; the in vivo study shows that the extract, at the administered
Quality control in the diagnosis of <em>Trichuris trichiura</em> and <em>Ascaris lumbricoides</em> using the Kato-Katz technique: experience from... (Publications)
(1.94%) and 6 (0.42%) instances for T. trichiura and A. lumbricoides, respectively. A high frequency of discordant results in FECs was observed (i.e. 10.0-23.9% for T. trichiura, and 9.0-11.4% for A. l [...] control, very low rates of false-positive results were observed; 0.35% (n inverted question mark= inverted question mark5) for T. trichiura and 0.28% (n inverted question mark= inverted question mark4) for
Biomarkers of host response predict primary end-point radiological pneumonia in Tanzanian children with clinical pneumonia: a prospective cohort study (Publications)
positive likelihood ratio 4.9 (3.4-7.1), negative likelihood ratio 0.083 (0.022-0.32), and misclassification rate 0.20 (standard error 0.038). CONCLUSIONS: In Tanzanian children with WHO-defined clinical
