Studies on <em>Dipetalonema viteae</em> (Filarioidea). 3. Antibody-dependent cell-mediated destruction of microfilariae<em> in vivo</em> (Publications)
using a micropore chamber technique. Microfilariae were eliminated within 24 hours in chambers of 3.0 and 5.0 microm pore size when implanted into amicrofilaremic hamsters (week 30 post infection). At peak [...] (week 12 post infection), only some hamsters could efficiently destroy microfilariae. In chambers with 0.3 microm pore size, microfilariae survived for more than 3 weeks in all hamsters. In uninfected hamsters
Effectiveness of a chlorhexidine dressing on silver-coated external ventricular drain associated colonization/infection - a prospective single-blinded... (Publications)
Cutaneous bacterial regrowth at the EVD exit wound was significantly reduced over time (OR 0.18, 95% CI 0.08, 0.42, p
Phytochemical study of <em>Salvia leriifolia</em> roots: rearranged abietane diterpenoids with antiprotozoal activity (Publications)
IC50 values of 0.4 and 33.6 muM, respectively, and a selectivity index of 84. Compound 2 displayed activity against T. brucei, T. cruzi, and L. donovani, with IC50 values of 1.0, 4.6, and 1.0 muM, respectively
Efficacy of triclabendazole and albendazole against <em>Fasciola </em>spp. infection in cattle in Côte d'Ivoire: a randomised blinded trial (Publications)
triclabendazole (95.4%) compared to those receiving albendazole (70.3%; odds ratio [OR] 0.11, 95% confidence interval [CI] 0.03-0.39, p
Absence of anti-hepatitis B surface antibody after vaccination does not necessarily mean absence of immune response (Publications)
were found to be significantly higher in the nonresponders (0.038) and in the vaccinees having lost anti-HBs (0.041), than in the controls (0.025). Such findings contribute to explaining why so-called
Synthesis of bicyclic amines and their activities against <em>Trypanosoma brucei rhodesiense</em> and <em>Plasmodium falciparum</em> K1 (Publications)
their N-benzyl derivatives showed decreased antiplasmodial but enhanced antitrypanosomal (IC50 = 0.22-0.41 microM) activities compared to their parent oximes and to formerly synthesized 4-amino-2-azabicyclo[3 [...] pyrimethamine) using in vitro microplate assays. 4-Aminobicyclo[2.2.2]oct-2-enes and 3-azatricyclo[3.2.2.0(2,4)]nonylamines exhibit similar antiprotozoal activities as 4-aminobicyclo[2.2.2] octanes. 4-Aminobicyclo[2
Independent at heart: persistent association of altitude with ischaemic heart disease mortality after consideration of climate, topography and built... (Publications)
mortality linearly decreased with increasing altitude resulting in a lower risk (HR, 95% CI 0.67, 0.60 to 0.74) for those living > 1500 m (vs
Incidence, risk factors, and outcome of aspiration pneumonitis in ICU overdose patients (Publications)
pneumonitis was associated with a higher incidence of cardiac arrest (6.4 vs 0.9%; p[Symbol: see text]=[Symbol: see text]0.037) and an increased duration of both ICU stay and overall hospital stay [re [...] [respectively: median 1 (interquartile range 1-3) vs 1 (1-2), p[Symbol: see text]=[Symbol: see text]0.025; and median 2 (1-7) vs 1 (1-3), p[Symbol: see text]
Antitrypanosomal and antiplasmodial activity of medicinal plants from Côte d' Ivoire (Publications)
(Annonaceae) and Trichilia emetica (Meliaceae) were the most promising ones. Their IC50 values were 0.5 and 0.04 microg/ml, respectively, and the selectivity index 616 and 209, respectively. This is the first [...] below 4 microg/ml. The highest activity was found for Enantia polycarpa stem bark with an IC50 value of 0.126 microg/ml.
Pacing pattern and performance during the 2008 Olympic rowing regatta (Publications)
the heats, the pacing pattern adopted during the finals was significantly different (females: P0.013; males: P0.001); that is, relatively slower in the first and second race quarter but relatively faster [...] revealed that absolute times in the second and/or third race quarter(s) were significantly (both sexes: P0.001) longer than those either in the first or final quarter, resulting in a parabolic-shaped profile
