Spatial analysis of schistosomiasis in Hunan and Jiangxi provinces in the People's Republic of China (Publications)
with the spatial distribution of infection. Prevalence of schistosomiasis was higher in Hunan (12.8%) than Jiangxi (2.6%). Spatial distribution of schistosomiasis varied at pixel level (0.1 x 0.1 km)
Steering away from current amoxicillin dose reductions in hospitalized patients with impaired kidney function to avoid subtherapeutic drug exposure (Publications)
resulted in a clinically relevant reduction in the PTA for the nonspecies-related PK/PD breakpoint MIC of 8 mg/L (92%, 62% and 38% with a CKD-EPI of 10, 20 and 30 mL/min/1.73 m(2), respectively, versus 100% for
Stringency of COVID-19 containment response policies and air quality changes: a global analysis across 1851 cities (Publications)
during moderate CRPs and even increased during mild CRPs by 2.3% (95% CI: 0.7, 4.0%), which was 6.8% (95% CI: 2.0, 12.0%) across Europe and Central Asia, possibly due to population avoidance of public
Projected impact of heat on mortality and labour productivity under climate change in Switzerland (Publications)
productivity amount to around CHF 665 million (approx. USD 700 million) per year. Should we remain on an RCP8.5 emissions pathway, these values may double (for mortality) or even triple (for labour productivity)
Evaluation of a physical activity and multi-micronutrient intervention on cognitive and academic performance in South African primary schoolchildren (Publications)
adjusting for baseline scores, school classes and age; 932 children (458 girls (49.1%), Mage (mean age) = 8.42 +/- 1.94 years) completed baseline and post-intervention assessments. Cognitive performance improved
High-throughput <em>Plasmodium falciparum hrp2</em> and <em>hrp3 </em>gene deletion typing by digital PCR to monitor malaria rapid diagnostic test... (Publications)
by ddPCR and nPCR. No deletions were observed by ddPCR, while by nPCR hrp2 deletion was observed in 8% of samples. The ddPCR assay was applied to screen 830 samples from Kenya, Zanzibar/Tanzania, Ghana
Metabolic, pharmacokinetic, and activity profile of the liver stage antimalarial (RC-12) (Publications)
The catechol derivative RC-12 (WR 27653) (1) is one of the few non-8-aminoquinolines with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model
Isolation and structural elucidation of compounds from <em>Pleiocarpa bicarpellata</em> and their <em>in vitro</em> antiprotozoal activity (Publications)
isolated, tubotaiwine (13) displayed the most significant antiplasmodial activity with an IC50 value of 8.5 microM and a selectivity index of 23.4. Therefore, P. bicarpallata extract can be considered as a
Spatial and temporal variations in PM10 concentrations between 2010-2017 in South Africa (Publications)
during the winter season. Temporally, the highest weekly PM10 concentrations of 51.4 microg/m(3), 46.8 microg/m(3), 29.1 microg/m(3) and 25.1 microg/m(3) at Gauteng, Mpumalanga, KwaZulu-Natal and Western
Dietary patterns measured by principal component analysis and its association with stunting among Nepalese schoolchildren in Nepal (Publications)
among schoolchildren. Method This cross-sectional study gathered data from 708 schoolchildren aged 8-16 years participating in the baseline survey in the Districts of Dolakha and Ramechhap, Nepal. We derived