Activities of N,N' -diarylurea MMV665852 analogs against <em>Schistosoma mansoni</em> (Publications)
compounds killed NTS and adult worms within 72 hours, respectively. Nine compounds had IC90 values /= 2.8. The physicochemical properties and permeation through an artificial membrane indicated good to moderate
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria (Publications)
pharmacokinetic properties of DSM265 are predicted to provide therapeutic concentrations for more than 8 days after a single oral dose in the range of 200 to 400 mg. DSM265 was well tolerated in repeat-dose
Meta-analysis identifies seven susceptibility loci involved in the atopic march (Publications)
allergic disease for the first time; rs9357733 located in EFHC1 on chromosome 6p12.3 (OR 1.27; P=2.1 x 10(-8)) and rs993226 between TMTC2 and SLC6A15 on chromosome 12q21.3 (OR 1.58; P=5.3 x 10(-9)). Additional
Ambient air pollution exposure estimation for the Global Burden of Disease 2013 (Publications)
most high income countries. Population-weighted mean concentrations of ozone increased globally by 8.9% from 1990-2013 with increases in most countries-except for modest decreases in North America, parts
Diagnosis, treatment and risk factors of <em>Strongyloides stercoralis</em> in schoolchildren in Cambodia (Publications)
24.4%, after analyzing three stool samples, which was close to the modeled 'true' prevalence of 24.8%. Children who reported defecating in latrines were significantly less infected with S. stercoralis
Rapid identification of paragonimiasis foci<em> </em>by lay informants in Lao People's Democratic Republic (Publications)
examined three sputa of suspected patients for the presence of Paragonimus eggs and acid fast bacilli. 91.8% of village leaders participated and notified a total of 220 suspected patients; 76.2% were eventually
2009 pandemic influenza A (H1N1) virus outbreak and response - Rwanda, October, 2009-May, 2010 (Publications)
= 510) were influenza A and 4% (n = 22) were influenza B. Of cases testing influenza A positive, 96.8% (n = 494), 3% (n = 15), and 0.2% (n = 1) were A(H1N1)pdm09, Seasonal A(H3) and Seasonal A(non-subtyped)
Improvements on restricted insecticide application protocol for control of human and animal African trypanosomiasis in eastern Uganda (Publications)
Poisson and logistic random effect models in R and STATA V12.1 respectively. Incidence was estimated at 9.8/100 years in RAP regimens, significantly lower compared to 25.7/100 years in the non-RAP regimens (incidence
Cost-effectiveness of iron supplementation and malaria chemoprophylaxis in the prevention of anaemia and malaria among Tanzanian infants (Publications)
from the perspective of the health provider, the cost-effectiveness ratios were, respectively, US$ 8, US$ 9, and US$ 21 per disability-adjusted life year (DALY) for malaria chemoprophylaxis with Deltaprim
Antiprotozoal, antimycobacterial and cytotoxic potential of twenty-three British and Irish red algae (Publications)
rhodesiense, with Corallina officinalis and Ceramium virgatum being the most potent (IC(50) values 4.8 and 5.4 mug/ml), whilst none of the algal extracts inhibited the growth of T. cruzi. Except for Porphyra
