Approved oncology drugs lack <em>in vivo</em> activity against <em>Trichuris muris</em> despite <em>in vitro</em> activity (Publications)
on the adult worm stage (> 80 % drug effect at 50 muM), of which six revealed IC50 values between 1.8 and 5.0 muM. Except for tamoxifen citrate, all in vitro active drugs were protein kinase inhibitors
Association between serum vitamin D, retinol and zinc status, and acute respiratory infections in underweight and normal-weight children aged 6-24... (Publications)
children with sufficient status. Underweight children, those with serum retinol deficiency were at 1.8 [95% confidence interval (CI) 1.4-2.4] times higher risk of ALRI than those with retinol sufficiency
Asymptomatic and sub-microscopic malaria infection in Kayah State, eastern Myanmar (Publications)
Plasmodium spp. infection was 2.3% (11/485) by real-time PCR. Plasmodium vivax accounted for 72.7% (8/11) and Plasmodium falciparum for 27.3% (3/11) of infections. Men were at greater risk of infection
IgE levels, atopy markers and hay fever in relation to age, sex and smoking status in a normal adult Swiss population (Publications)
concentrations (assessed by means of the Phadiatop test) and on the prevalence of hay fever. A total of 8,344 subjects aged 18-60 years, comprising 2,776 current smokers, 1,888 former smokers and 3,680 nonsmokers
<em>SERPINA1</em> gene variants in individuals from the general population with reduced {alpha}1-antitrypsin concentrations (Publications)
and from 93 to 103 mg/dL, individuals with the PI*MM genotype represented the majority (86.5% and 53.8%, respectively). The PI*MS genotype was predominant (54.9%) in the AAT range of 83 to 93 mg/dL, whereas
Perceptions on the effect of small electric fans on comfort inside bed nets in southern Ghana: a qualitative study (Publications)
a larger evaluation conducted in communities without electricity in rural Ghana to assess whether 0.8 W solar powered net fans can increase net use. METHODS: Twenty-three key informant interviews with household
Differences in indoor versus outdoor concentrations of ultrafine particles, PM2.5, PMabsorbance and NO2 in Swiss homes (Publications)
generally low in rural homes. Average indoor levels were 7800 particles/cm3 (interquartile range=7200); 8.7 mug/m3 (6.5) PM2.5 and 10.2 mug/m3 (11.2) NO2. All pollutants showed large variability of indoor/outdoor
Relative validation of a food frequency questionnaire to estimate food intake in an adult population (Publications)
moderate validity. More than half the food groups were overestimated in the FFQ, especially vegetables (82.8%) and fruits (56.3%). Water, tea and coffee were underestimated (-14.0%). Conclusions: The FFQ showed
Effects of liver-stage clearance by Primaquine on gametocyte carriage of <em>Plasmodium vivax</em> and <em>P. falciparum</em> (Publications)
plus either PQ or placebo. Blood samples were subsequently collected in 2-to 4-weekly intervals over 8 months. Gametocytes were detected by quantitative reverse transcription-PCR targeting pvs25 and pfs25
Live and stillborn very low birthweight infants in Switzerland: comparison between hospital based birth registers and the national birth register (Publications)
. If these infants are included, the national perinatal mortality rate would increase from 6.9‰ to 8.0‰. Reasons for underreporting are unclear but may be due to varying definitions of stillbirth and different
