A near-complete series of four atropisomeric jozimine A2-Type naphthylisoquinoline dimers with antiplasmodial and cytotoxic activities and related... (Publications)
fibrosarcoma (HT1080), and multiple myeloma (MM.1S) cancer cells, displaying IC50 values of 12.0, 9.0, and 5.0 muM, respectively, whereas jozibrevines A (1a) and B (1b) were nontoxic in this concentration [...] antiplasmodial activities in the submicromolar range, with 1a being the most potent compound (IC50, 0.012 muM). Furthermore, jozimine A2 (1d) showed cytotoxicity against human colon carcinoma (HT-29),
qRT-PCR versus IFA-based quantification of male and female gametocytes in low-density <em>Plasmodium falciparum</em> infections and their relevance... (Publications)
qRT-PCR. The mean proportion of males was 0.39 (95% confidence interval, 0.33-0.44) by pfs25/pfmget qRT-PCR; this correlated well with IFA results (Pearsons r2 = 0.91; P < .001). A Poisson model fitted to
Azaterphenyl diamidines as antileishmanial agents (Publications)
compounds gave IC50 values less than 1 microM, five exhibited values less than 0.40 microM, and two gave values less than 0.10 microM in a Leishmania donovani axenic amastigote assay. The activity of the
Azaterphenyl diamidines as antileishmanial agents (Publications)
compounds gave IC50 values less than 1 microM, five exhibited values less than 0.40 microM, and two gave values less than 0.10 microM in a Leishmania donovani axenic amastigote assay. The activity of the
Serological study of <em>Leptospira interrogans</em> serovar Copenhageni and <em>L. borgpetersenii</em> serovars Tarassovi and Ballum in beef cattle,... (Publications)
respectively, was 13.7 (95% CI=11.7-16.0)%, 12.6 (95 CI=10.6-14.7)% and 18.0 (95% CI=15.7-20.5)% for beef cattle, 10.5 (95% CI=9.0-12.1)%, 16.7 (95% CI=14.9-18.6)% and 14.0 (95% CI=12.4-15.8)% for sheep and [...] CI=2.7-4.8)% for deer, respectively. Herd/flock-level seroprevalence for Ballum was 86.6, 52.4 and 39.0% for sheep, 85.2, 52.7 and 33.3% for beef cattle and 50.8, 27.9 and 21.3% for deer at definitions > [...] data were 95.1, 73.2 and 56.1% for sheep, 68.5, 48.2 and 29.6% for beef...
Serological study of <em>Leptospira interrogans</em> serovar Copenhageni and <em>L. borgpetersenii</em> serovars Tarassovi and Ballum in beef cattle,... (Publications)
respectively, was 13.7 (95% CI=11.7-16.0)%, 12.6 (95 CI=10.6-14.7)% and 18.0 (95% CI=15.7-20.5)% for beef cattle, 10.5 (95% CI=9.0-12.1)%, 16.7 (95% CI=14.9-18.6)% and 14.0 (95% CI=12.4-15.8)% for sheep and [...] CI=2.7-4.8)% for deer, respectively. Herd/flock-level seroprevalence for Ballum was 86.6, 52.4 and 39.0% for sheep, 85.2, 52.7 and 33.3% for beef cattle and 50.8, 27.9 and 21.3% for deer at definitions > [...] data were 95.1, 73.2 and 56.1% for sheep, 68.5, 48.2 and 29.6% for beef...
Distribution of bovine <em>Fasciola gigantica</em> (Cobbold, 1885) in the district des Savanes, northern Côte d'Ivoire (Publications)
considerable spatial heterogeneity, both at regional (ranging from 18.0% to 52.3%) and departmental level (ranging from 14.3% to 64.0%). Poro region was the most affected (52.3%) with a relatively homogeneous [...] homogeneous distribution. The departments most affected by fascioliasis were M'Bengue (64.0%), Sinematiali (62.1%) and Ferkessedougou (52.9%). Our study confirms that fascioliasis is an important veterinary
Achieving high coverage of larval-stage mosquito surveillance: challenges for a community-based mosquito control programme in urban Dar es Salaam,... (Publications)
associated with his/her unfamiliarity with the area (Odds Ratio (OR) [95% confidence interval (CI)] = 0.16 [0.130, 0.203], P
Do topical repellents divert mosquitoes within a community? Health equity implications of topical repellents as a mosquito bite prevention tool (Publications)
half that of households in the no coverage scenario (Incidence Rate Ratio [IRR]=0.39 (95% confidence interval [CI]: 0.25-0.60); p
Risk factors for helminth infections in a rural and a peri-urban setting of the Dongting Lake area, People's Republic of China (Publications)
single infections of S. japonicum, A. lumbricoides, hookworm and T. trichiura were 6.5%, 5.5%, 3.0% and 0.8%, respectively; the majority of the infections were of light intensity. We found significant negative [...] lumbricoides. Clinical manifestations of splenomegaly, hepatomegaly and anaemia were prevalent (9.0%, 3.7% and 10.9%, respectively), the latter two being significantly (P
