Enhanced fibrin formation in high-altitude pulmonary edema (Publications)
was elevated in HAPE to 4.2 +/- 2.7 ng/ml (P less than 0.0001) compared with the other groups showing mean values between 1.6 +/- 0.4 and 1.8 +/- 0.7 ng/ml. FPA was normal in one patient with HAPE, however
Birth weight and carotid artery intima-media thickness (Publications)
and parental health.RESULTS: Mean CIMT was 0.57 mm (SD 0.04). We found a nonlinear association between birth weight and CIMT, with an increase in CIMT of 0.014 mm in the fifth (P value .01) compared with
Novel orally active antimalarial thiazoles (Publications)
carboxamide lead 3 with good in vitro antiplasmodial activity [IC(50): 0.08 muM (K1, chloroquine and multidrug resistant strain) and 0.07 muM (NF54, chloroquine sensitive strain)] and microsomal metabolic [...] toxicity profiling, 3 exhibited moderate potential to inhibit CYP1A2 (IC(50) = 1.5 muM) and 2D6 (IC(50) = 0.4 muM) as well as having a potential hERG liability (IC(50) = 3.7 muM)
Evaluation of efficacy of community-based vs. institutional-based direct observed short-course treatment for the control of tuberculosis in Kilombero... (Publications)
cure rates between the two strategies [M-H pooled odds ratio (OR) 0.62; 95% confidence interval (CI) 0.23, 1.71 and OR = 1.58; 95% CI 0.32, 7.88, respectively] suggesting that CBDOT may be a viable alternative
High prevalence of nonconvulsive and subtle status epilepticus in an ICU of a tertiary care center: a three-year observational cohort study (Publications)
course (OR: 5.135; p=0.0029). Hospital stay increased by 1.13h with each additional hour of status epilepticus (p=0.02). Subtle status epilepticus was a risk factor for refractoriness (p=0.0065). CONCLUSIONS:
Effects of everyday radiofrequency electromagnetic-field exposure on sleep quality: a cross-sectional study (Publications)
ts had an estimated risk for sleep disturbances of 1.11 (95% CI: 0.50 to 2.44) and for excessive daytime sleepiness of 0.58 (95% CI: 0.31 to 1.05). Neither mobile phone use nor cordless phone use was
The association between road traffic noise exposure, annoyance and health-related quality of life (HRQOL) (Publications)
in modelled noise exposure by 10 dB(A) resulted in a von Zerssen symptom score increase of 0.47 (95% CI: -0.01, 0.95) units. Subsequent structural equation modelling revealed that the association between
Sex-specific associations of cardiovascular risk factors with carotid stiffness - results from the SAPALDIA cohort study (Publications)
sexes (ranges of CS parameters: -3.7; -0.8% of changes in geometric mean per 1SD of the risk factor on an inverted scale) and significant adverse risk factors were BMI (-0.5; 4.7%), systolic (-1.23; 4.7%) and [...] and diastolic blood pressure (1.4; 4.4%), heart rate (2.7; 7.9%), C-reactive protein (0.6; 3.3%) and smoking (-2.82; 1%), all p-values of multivariate analyses were
Pathways and associated costs of care in patients with confirmed and presumptive tuberculosis in Tanzania: a cross-sectional study (Publications)
presumptive patients (USD 27.4 [IQR 18.7-48.4] vs USD 19.8 [IQR 13.8-34.0], p=0.02), as were the indirect costs (USD 66.9 [IQR 35.5-150.0] vs USD 46.8 [IQR 20.1-115.3], p
Evaluation of the Clinitek®, a point-of-care urinalysis system for the measurement of clinically significant urinary metabolites and detection of... (Publications)
and haematuria was observed (kappa coefficient of 0.88 and 0.82, respectively), while a good correlation was observed for leukocytes (kappa coefficient of 0.63) A moderate to fair correlation was calculated
