The influence of sampling effort and the performance of the Kato-Katz technique in diagnosing <em>Schistosoma mansoni</em> and hookworm co-infections... (Publications)
smear for detection of S. mansoni alone, hookworms alone, or S. mansoni plus hookworms were 22.4%, 8.0% and 17.7%, respectively. In the current setting this could be attributable to low infection intensities
Progression to active tuberculosis, but not transmission, varies by <em>Mycobacterium tuberculosis</em> lineage in The Gambia (Publications)
exposed to M. tuberculosis (1.0% vs. 2.9%; hazard ratio [HR], 3.1 [95% confidence interval {CI}, 1.1-8.7]). Within M. tuberculosis sensu stricto, contacts exposed to a Beijing family strain were most likely
Evaluation of antiprotozoal and antimycobacterial activities of the resin glycosides and the other metabolites of <em>Scrophularia cryptophila</em> (Publications)
Leishmania donovani. Harpagide (4) and 3 emerged as the best leishmanicidal agents (IC(50)'s 2.0 and 5.8 microg/ml). Only compounds 3, 6 and 7 showed antimalarial activity against Plasmodium falciparum with
The outpatient cost of diabetes care in Italian diabetes centers (Publications)
centers for diabetes care in Italy. RESULTS: The per-patient cost of treatment was [symbol: see text] 136.8 in two months for type I diabetes (N = 592) and [symbol: see text] 123.3 for type II diabetes (N = 1668)
Diphenyl furans and aza analogs: effects of structural modification on in vitro activity, DNA binding, and accumulation and distribution in... (Publications)
the compounds investigated accumulated to millimolar concentrations in trypanosomes over a period of 8 h. Interestingly, some of the less potent compounds accumulated to concentrations much higher than those
Mass screening and treatment on the basis of results of a <em>Plasmodium</em> <em>falciparum</em>-specific rapid diagnostic test did not reduce... (Publications)
intervals: 0.1-0.3%) in both rounds compared to a PCR positivity (all species) of 2.5% (2.1-2.9%) and 3.8% (3.2-4.4%) in rounds 1 and 2, respectively. Two fifths (40%) of infections detected by PCR included
Activities of N,N' -diarylurea MMV665852 analogs against <em>Schistosoma mansoni</em> (Publications)
compounds killed NTS and adult worms within 72 hours, respectively. Nine compounds had IC90 values /= 2.8. The physicochemical properties and permeation through an artificial membrane indicated good to moderate
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria (Publications)
pharmacokinetic properties of DSM265 are predicted to provide therapeutic concentrations for more than 8 days after a single oral dose in the range of 200 to 400 mg. DSM265 was well tolerated in repeat-dose
Meta-analysis identifies seven susceptibility loci involved in the atopic march (Publications)
allergic disease for the first time; rs9357733 located in EFHC1 on chromosome 6p12.3 (OR 1.27; P=2.1 x 10(-8)) and rs993226 between TMTC2 and SLC6A15 on chromosome 12q21.3 (OR 1.58; P=5.3 x 10(-9)). Additional
Ambient air pollution exposure estimation for the Global Burden of Disease 2013 (Publications)
most high income countries. Population-weighted mean concentrations of ozone increased globally by 8.9% from 1990-2013 with increases in most countries-except for modest decreases in North America, parts
