Number of comorbidities and their impact on perioperative outcome and costs: a single centre cohort study (Publications)
median number of comorbidities per patient was 5 (range 0-18), this number significantly increasing with higher ASA class: 1 comorbidity (95% CI 0.0-2.0) in ASA I, 4 comorbidities (3.8-4.2) in ASA II, 9 (8
Rapid suppression of HIV-RNA is associated with improved control of immune activation in Mozambican adults initiating antiretroviral therapy with low... (Publications)
if locked into a multivariate model [EFV OR: 13.6 (95% CI 1.7; 108.1) p = 0.014) tuberculosis OR: 11.0 (95% CI 1.4; 87.9) p = 0.024]. EC demonstrated significantly lower median activated CD8 T cells at [...] experienced reappearance of detectable HIV-RNA at 6 months postcontrol as compared to 15% (2/60) of EC (p = 0.001). This study suggests that rapid suppression of HIV-RNA may lead to a lower rate of reappearance
Weight status and gender-related differences in motor skills and in child care-based physical activity in young children (Publications)
4 +/-0.6 years, BMI 16.2 +/- 1.2 kg/m2), 13% were overweight. There were no significant weight status-related differences in the single skills of the obstacle course, but there was a trend (p = 0.059) [...] skills score, but boys performed better than girls in 2 of the 5 motor skills (p [less than or equal to] 0.04). Total physical activity as well as time spent in moderate-vigorous and in vigorous activity during [...] during child care were 12-25% higher and sedentary activity 5% lower in boys...
Artemisinin-based combination therapy does not measurably reduce human infectiousness to vectors in a setting of intense malaria transmission (Publications)
increased oocyst prevalence (OR [95%CI] = 3.9 [2.9-5.3], p < 0.001), but had no consistent effect on sporozoite prevalence (OR [95%CI] = 0.9 [0.7-1.2], p = 0.5). The estimated infectiousness of the human population
Accuracy of urine circulating cathodic antigen test for the diagnosis of <em>Schistosoma mansoni</em> in preschool-aged children before and after... (Publications)
CCA(t-) and CCA(t+) was 4.0%, 80.0% and 84.0%, respectively. The intensity of the POC-CCA test band reaction was correlated with S. mansoni egg burden (odds ratio = 1.2, p = 0.04). CONCLUSIONSSIGNIFICANCE:
Costing the supply chain for delivery of ACT and RDTs in the public sector in Benin and Kenya (Publications)
chain costs added USD 0.2011 to the initial acquisition cost of ACT and USD 0.3375 to RDTs (normalized to USD 1). In Kenya, they added USD 0.2443 to the acquisition cost of ACT and USD 0.1895 to RDTs (normalized
Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea (Publications)
However, An. punctulatus was significantly more likely than An. farauti s.s. (OR 0.14; p = 0.007) or An. koliensis (OR 0.27; p < 0.001) to carry P. falciparum sporozoites. CONCLUSIONS: LLINs had a significant
Improved retention rates with low-cost interventions in hypertension and diabetes management in a rural African environment of nurse-led care: a... (Publications)
intervention groups and the control group were significant (P < 0.001), but differences between the two intervention groups were not (P = 0.719). There were no significant differences in BP or fasting plasma [...] for antihypertensive medication was euro 1.1 +/- 0.9 and for diabetics euro1.2 +/- 1.1. Transport costs to the centres were on average euro1.1 +/- 1.0 for hypertensive patients and euro1.1 +/- 1.6 for
AID protein expression in chronic lymphocytic leukemia/small lymphocytic lymphoma is associated with poor prognosis and complex genetic alterations (Publications)
proliferation rate (P=0.012). ATM deletion was detected in 10% (6/63) of patients and p53 deletion in 19% (13/67) of patients. Moreover, both ATM (P=0.002) and p53 deletion (P=0.004) were significantly [...] AID-negative chronic lymphocytic leukemia/small lymphocytic lymphoma patients (61 vs 130 months, P=0.001). Although there was a trend, we could not show an association with the IgV(H) gene mutation status
The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and... (Publications)
one A-allele was associated with a decreased risk among all remaining subjects (OR=0.56; 0.36-0.86) (P for interaction=0.01). Recent studies indicate that ITCs inhibit cell proliferation and cause apoptosis
