Colloidal transformations in MS2 virus particles: driven by pH, influenced by natural organic matter (Publications)
spherical with core-shell-type structure with a total diameter of 27 nm and a core radius of around 8 nm. Reversible transformations from 27 nm particles at pH = 7.0 to micrometer-sized aggregates at pH
Disability progression among leprosy patients released from treatment: a survival analysis (Publications)
complaints of any kind during treatment were identified as risk factors with Hazard Ratios of 1.6 and 1.8 respectively. CONCLUSIONS: People released from treatment as cured of leprosy are susceptible to worsening
Influence of parasite density and sample storage time on the reliability of <em>Entamoeba histolytica</em>-specific PCR from formalin-fixed and... (Publications)
density, and reliability of PCR was analyzed. E. histolytica PCR was positive in 20 of 34 biopsies (58.8%); 2 of these 20 were microscopically negative for amebae in neighboring tissue sections. PCR was negative
The molecular clock of <em>Mycobacterium tuberculosis</em> (Publications)
clock of MTB. For data sets where such calibration was possible, we obtained a clock rate between 1x10-8 and 5x10-7 nucleotide changes per-site-per-year (0.04-2.2 SNPs per-genome-per-year), with substantial
Non-randomized studies using causal-modelling may give different answers than RCTs: a meta-epidemiological study (Publications)
RCTs (120669 patients). MSM-studies indicated effect estimates in the opposite direction from RCTs for 8 clinical questions (42%), and their 95% CI did not include the RCT estimate in 9 clinical questions
Synthesis, <em>in-vitro</em> antiprotozoal activity and molecular docking study of isothiocyanate derivatives (Publications)
Leishmania donovani with IC50 values between 0.4 and 1.0microM and selectivity index (SI) ranged from 7.8 to 18.4, comparable to the standard drug miltefosine (IC50=0.7muM). Compound 7h demonstrated the best
Association of adult lung function with accelerated biological aging (Publications)
1-PAI1) and their related age-adjusted measures were estimated from peripheral blood at two time points (8-to-11 years apart) in adults from two cohorts: SAPALDIA (n=987) and ECRHS (n=509). Within each cohort
Legionnaires' disease in Switzerland: rationale and study protocol of a prospective national case-control and molecular source attribution study... (Publications)
Switzerland has one of the highest annual Legionnaires' disease (LD) notification rates in Europe (7.8 cases/100,000 population in 2021). The main sources of infection and the cause for this high rate remain
A multi-pronged approach to improve blood culture diagnostics in different clinical departments: a single-centre experience (Publications)
were fully trained. The intervention led to a considerable increase in BC knowledge (from 62.4 to 79.8% correct answers) with differences between the individual professional groups. Relevant reduced con
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a preliminary survey among patients in Switzerland (Publications)
gastro-intestinal infections (15.4%) and tick-borne diseases (16.2%). Viral infections were recalled by 77.8% of the respondents, with Epstein Barr Virus being the most commonly reported agent. Patients self-reported
