Mass screening and treatment on the basis of results of a <em>Plasmodium</em> <em>falciparum</em>-specific rapid diagnostic test did not reduce... (Publications)
population (n=7859) were screened at least once. P. falciparum prevalence by RDT was 0.2% (95% confidence intervals: 0.1-0.3%) in both rounds compared to a PCR positivity (all species) of 2.5% (2.1-2.9%) and
Copeptin levels remain unchanged during the menstrual cycle (Publications)
change during the menstrual cycle (p = 0.16). Throughout the menstrual cycle, changes in estradiol (p = 0.002) and in the physical premenstrual symptom score (p = 0.01) were positively related to copeptin
Diagnostic accuracy of computer-aided detection of pulmonary tuberculosis in chest radiographs: a validation study from sub-Saharan Africa (Publications)
under the ROC curve of CAD4TB for the detection of culture-positive pulmonary tuberculosis was 0.84 (95% CI 0.80-0.88). CAD4TB was significantly more accurate for the discrimination of smear-positive cases
Low risk for transmission of zoonotic <em>Giardia duodenalis</em> from dogs to humans in rural Cambodia (Publications)
BIII of G. duodenalis. In dogs, 20.0% (2/10) of Giardia-positive samples were characterised as G. duodenalis assemblage BIII, 40.0% (4/10) as assemblage C and 40.0% (4/10) as mix infection between assemblage
Improvements on restricted insecticide application protocol for control of human and animal African trypanosomiasis in eastern Uganda (Publications)
significantly lower compared to 25.7/100 years in the non-RAP regimens (incidence rate ratio: 0.37; 95% CI: 0.22-0.65; P
Do instructional videos on sputum submission result in increased tuberculosis case detection? A randomized controlled trial (Publications)
technicians blinded to study groups. RESULTS: Median age was 39.1 years (interquartile range 37.0-50.0); 94 (47%) were females, 106 (53%) were males, and 49 (24.5%) were HIV-infected. We found that the [...] 23%, 95% CI 15.2-32.5%, in the control group, p /=3ml (78%, 95% CI 68.6-85.7%, versus 45%, 95% CI 35.0-55.3%, p
Living near main streets and respiratory symptoms in adults (Publications)
confidence interval: 0, 22) per 100-m increment in distance from home to a main street. Living within 20 m of a main street increased the risks of regular phlegm by 15% (95% confidence interval: 0, 31) and wheezing [...] wheezing with breathing problems by 34% (95% confidence interval: 0, 79) in never smokers. In 2002, the effects related to road distance were different from those in 1991, which could be due to changes in
PM10 and children's respiratory symptoms and lung function in the PATY study (Publications)
Confidence Interval 1.02-1.30), hay fever (1.20 (0.99-1.46)), bronchitis (1.08 (0.98-1.19)), morning cough (1.15 (1.02-1.29)) and nocturnal cough (1.13 (0.98-1.29)). There were no associations with diagnosed
Anti-trypanosomal activity of Fexinidazole: a new oral nitroimidazole drug candidate for the treatment of sleeping sickness (Publications)
The parent molecule and both metabolites have shown trypanocidal activity in vitro in the 0.7 - 3.3 muM (0.2 to 0.9 mug/ml) range against all parasite strains tested. In vivo fexinidazole is orally effective
Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with <em>Fasciola hepatica</em> in sheep (Publications)
half-life of 1.0h and a mean AUC of 116.2+/-47mugmin/ml was calculated for the oral administration. Following subcutaneous treatment with OZ78 C(max) and t(max) were 13.7+/-6.1mug/ml and 0.9+/-0.4h, respectively
